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NCT06074601 · ClinicalTrials.gov registry record

MIRACLE of LIFE Study

A clinical trial of Preeclampsia and Preterm Birth, sponsored by Mirvie.

Active
Registry status
10,000
Enrollment target
10
Study locations

NCT06074601: Active study of Preeclampsia and Preterm Birth, sponsored by Mirvie.

NCT06074601 is a study of Preeclampsia and Preterm Birth that is active but no longer recruiting, run by Mirvie. The registered enrollment target is 10,000 participants, above the 918-participant average among 48 other Preeclampsia trials with a reported enrollment target (989% higher). The trial reports 10 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06074601, a study of Preeclampsia and Preterm Birth, is active but no longer recruiting, sponsored by Mirvie.

ACTIVE NOT RECRUITING
Registry status
10,000 participants
Enrollment target
10
Study locations

Study Summary

The goal of this observational study is to develop and validate cell-free RNA-based biomarkers for predicting a variety of adverse pregnancy outcomes in a pregnant person population. The main question it aims to answer are: 1. Can cell-free RNA-based biomarkers predict which pregnant people are at greatest risk of developing adverse pregnancy outcomes (e.g., preterm birth, preeclampsia)? 2. What is the performance of such biomarkers when predicting an adverse pregnancy outcome (e.g., sensitivity, specificity, PPV, NPV, TPR)?

Primary Outcome

This study will measure the test performance (e.g., ROC, sensitivity, specificity, negative and positive predictive value) of cell-free RNA-based biomarkers that are predictive of a variety of adverse pregnancy outcomes (e.g., preterm birth, preeclampsia)

Conditions Studied

Preeclampsia Preterm Birth Gestational Hypertension Gestational Diabetes Mellitus in Pregnancy Preterm Labor Preterm Premature Rupture of Membrane Intrauterine Growth Restriction Small for Gestational Age at Delivery Preterm Birth Complication HELLP

Interventions

  • DIAGNOSTIC_TEST Mirvie Predictive Test for Adverse Pregnancy Outcomes

Study Locations (10)

Pennsylvania

  • Thomas Jefferson University - Philadelphia
  • University of Pittsburgh Medical Center - Pittsburgh

California

  • University of California San Diego - San Diego

Florida

  • Women's Care Florida - Orlando

Louisiana

  • Ochsner Health System - New Orleans

Massachusetts

  • Beth Israel Deaconess Medical Center - Boston

Missouri

  • Washington University School of Medicine - St Louis

Ohio

  • The Ohio State University - Columbus

Texas

  • University of Texas Medical Branch - Galveston

Trial Details

FieldValue
Enrollment Target 10,000 participants
Start Date 2021-08-01
Est. Completion 2025-12-31
Mirvie

1 total trials

What the registry record for NCT06074601 still lists

NCT06074601 is an observational study that tracks outcomes without assigning an intervention. Its 10,000 participants enrollment target places it among the larger protocols in the corpus, above the 918-participant average among 48 other Preeclampsia trials with a reported enrollment target (989% higher).

The record links to 10 conditions, with Preeclampsia appearing as the primary indexed condition, and to 1 intervention - of which Mirvie Predictive Test for Adverse Pregnancy Outcomes is the first listed.

NCT06074601 lists 10 locations in 9 states (Pennsylvania, California, Florida).

Frequently Asked Questions

What is clinical trial NCT06074601 about?

NCT06074601 is a clinical study titled "MIRACLE of LIFE Study". The goal of this observational study is to develop and validate cell-free RNA-based biomarkers for predicting a variety of adverse pregnancy outcomes in a pregnant person population. The main question it aims to answer are: 1. Can cell-free RNA-based biomarkers predict which pregnant people are at ...

What is the current status of trial NCT06074601?

This trial is currently active not recruiting. The enrollment target is 10,000 participants. The study started on 2021-08-01. Estimated completion is 2025-12-31.

What conditions does trial NCT06074601 study?

This clinical trial studies the following conditions: Preeclampsia, Preterm Birth, Gestational Hypertension, Gestational Diabetes Mellitus in Pregnancy, Preterm Labor.

What interventions are being tested in trial NCT06074601?

The interventions under investigation include: Mirvie Predictive Test for Adverse Pregnancy Outcomes (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT06074601?

This trial is sponsored by Mirvie, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06074601 being conducted?

This trial has 10 study locations across California, Florida, Louisiana, Massachusetts, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Preeclampsia

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06074601's enrollment target sits among peer trials

10,000 3rd of 48 higher than 46 of 48 other Preeclampsia trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Preeclampsia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT06074601, the US trial registry maintained by the National Library of Medicine. NCT06074601 (large enrollment · multi site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.