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NCT06581536 · ClinicalTrials.gov registry record · NA
Rigorous Evaluation of Yes and Know, a Fully Virtual Sexual Health and Well-Being Intervention for Youth
A NA study of Pregnancy Related and Adolescent Behavior, sponsored by ETR Associates.
- Recruiting
- Registry status
- NA
- Development phase
- 1,200
- Enrollment target
- 1
- Study location
NCT06581536: Recruiting NA study of Pregnancy Related and Adolescent Behavior, sponsored by ETR Associates.
NCT06581536 is a NA study of Pregnancy Related and Adolescent Behavior that is actively recruiting participants, run by ETR Associates. The registered enrollment target is 1,200 participants, below the 1,951-participant average among 99 other Pregnancy Related trials with a reported enrollment target (38% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06581536, a NA study of Pregnancy Related and Adolescent Behavior, is actively recruiting participants, sponsored by ETR Associates.
- RECRUITING
- Registry status
- NA
- Development phase
- 1,200 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is a 2-arm cluster randomized controlled trial with approximately 1,200 youth aged 14-19 years to assess the effectiveness of Yes and Know, a sexual health education program. To be eligible, participants must be 14-19 years old and English-speaking. Those in the treatment arm will receive Yes and Know, a synchronous virtual program delivered over multiple sessions totaling nine hours, along with asynchronous online activities and resources. Those in the control arm will receive a similarly structured program focused on nutrition education. Participants will complete brief online surveys at baseline and at 3 and 12 months after the synchronous sessions. The study will assess the program's effectiveness in reducing the prevalence of unprotected sex among youth and improving short-term outcomes, such as knowledge of reproductive health and healthy relationships, self-efficacy, and the use of reproductive health services.
Primary Outcome
Single measure constructed from the number of times had vaginal sex without a contraceptive method in the past 3 months; number of times had anal sex without a condom in the past 3 months.
Conditions Studied
Interventions
- BEHAVIORAL Yes and Know curriculum
- BEHAVIORAL Nutrition Education for Adolescents
Study Locations (1)
California
- ETR Associates - Watsonville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,200 participants |
| Start Date | 2025-05 |
| Est. Completion | 2027-08-31 |
| Phase | NA |
What NCT06581536 shows while recruiting
NCT06581536 is an interventional study that assigns participants to a tested intervention. Its 1,200 participants enrollment target places it among the larger protocols in the corpus, below the 1,951-participant average among 99 other Pregnancy Related trials with a reported enrollment target (38% lower).
The record links to 3 conditions, with Pregnancy Related appearing as the primary indexed condition, and to 2 interventions - of which Yes and Know curriculum is the first listed.
NCT06581536 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06581536 about?
NCT06581536 is a clinical study titled "Rigorous Evaluation of Yes and Know, a Fully Virtual Sexual Health and Well-Being Intervention for Youth". This study is a 2-arm cluster randomized controlled trial with approximately 1,200 youth aged 14-19 years to assess the effectiveness of Yes and Know, a sexual health education program. To be eligible, participants must be 14-19 years old and English-speaking. Those in the treatment arm will receive...
What is the current status of trial NCT06581536?
This trial is currently recruiting. It is a NA study. The enrollment target is 1,200 participants. The study started on 2025-05. Estimated completion is 2027-08-31.
What conditions does trial NCT06581536 study?
This clinical trial studies the following conditions: Pregnancy Related, Adolescent Behavior, Sexually Transmitted Diseases.
What interventions are being tested in trial NCT06581536?
The interventions under investigation include: Yes and Know curriculum (BEHAVIORAL), Nutrition Education for Adolescents (BEHAVIORAL).
Who is sponsoring clinical trial NCT06581536?
This trial is sponsored by ETR Associates, which has 6 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06581536 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06581536's enrollment target sits among peer trials
1,200 13th of 99 higher than 87 of 99 other Pregnancy Related trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pregnancy Related trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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