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ClinicalTrials.gov 14 recruiting now official registry

Celiac Disease clinical trials

14 of 25 indexed Celiac Disease trials are currently recruiting.

25 US clinical trials · 14 currently recruiting

Celiac Disease is the subject of 25 registered US clinical trials on ClinicalTrials.gov, 14 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 10 in Phase 1-2 (earlier-stage). The most active sponsor is Nielsen Fernandez-Becker, running 2 of these trials.

The research picture

Celiac Disease has 25 registered US clinical trials, 14 of them open to new participants right now, about 56% of the total.

14
recruiting participants now
56%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
2
top sponsor: Nielsen Fernandez-Becker
Phase 14Phase 26

Active & Recent Trials

25 total, page 1 of 1

RECRUITING 33,000 participants

General Population Level Estimation for Type 1 Diabetes Risk in Children During Routine Care Delivery

Sanford Health

NCT04477928

RECRUITING 10,000 participants

Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research

Brain Inflammation Collaborative

NCT04806620

RECRUITING 1,250 participants

Urine Metabolites in the Diagnosis of Disease

Luventix

NCT06710067

RECRUITING 500 participants

Celiac Disease Genomic Environmental Microbiome and Metabolomic Study

Massachusetts General Hospital

NCT02061306

RECRUITING NA 400 participants

Immune Responses to Gluten

Boston Children's Hospital

NCT05209568

RECRUITING 300 participants

A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease

TScan Therapeutics

NCT06587828

RECRUITING NA 220 participants

Tissue Destruction and Healing in Celiac Disease

University of Chicago

NCT05680012

RECRUITING 200 participants

Accessing Care, Clinical Trials and Screening for Underserved Children and Adults With Type 1 Diabetes (ACCESS-T1D)

AdventHealth Translational Research Institute

NCT06908057

RECRUITING NA 200 participants

Gluten Technology and Education for Celiac Health

Columbia University

NCT06059716

RECRUITING Phase 2 92 participants

Study of DONQ52 in Active Celiac Disease

Chugai Pharmaceutical

NCT07239336

RECRUITING Phase 2 48 participants

A Trial to Assess the Efficacy and Safety of TEV-53408 in Adults With Celiac Disease

Teva Branded Pharmaceutical Products R&D

NCT06807463

RECRUITING Early Phase 1 45 participants

VTP-1000 in Adults With Celiac Disease

Barinthus Biotherapeutics

NCT06310291

RECRUITING Phase 2 40 participants

Double Blind, Placebo-controlled Trial to Establish Safety and Efficacy of Ritlecitinib in Celiac Disease Patients in Remission

Massachusetts General Hospital

NCT05636293

RECRUITING Phase 1 18 participants

A First-in-human Study to Evaluate the Safety and Tolerability of HB-2121 as a Diagnostic for Celiac Disease

Nielsen Fernandez-Becker

NCT07063823

ACTIVE NOT RECRUITING Phase 2 229 participants

A Phase 2a/b Study of the Efficacy and Safety of Subcutaneous Amlitelimab in Adults With Nonresponsive Celiac Disease

Sanofi

NCT06557772

COMPLETED 500 participants

Detection of Celiac Disease in Patients With Hypothyroidism

University of Vermont

NCT01862510

COMPLETED Phase 2 153 participants

A Study of TAK-062 in Treatment of Active Celiac Disease in Participants Attempting a Gluten-Free Diet

Takeda

NCT05353985

COMPLETED NA 84 participants

Validation of CapsoVision CapsoCam® SV-3 Capsule Endoscopy System

Capso Vision

NCT04573959

COMPLETED NA 60 participants

Changes in Intestinal Permeability 4 Hours After Gluten Challenge

Mayo Clinic

NCT03288831

COMPLETED Phase 2 55 participants

A Study of Efficacy, Safety, and Tolerability of KAN-101 in People With Celiac Disease

Kanyos Bio, Inc., a wholly-owned subsidiary of Anokion

NCT06001177

COMPLETED 40 participants

Gut Permeability Assessment in Celiac and Gluten Sensitive Children

Mayo Clinic

NCT02690532

COMPLETED Early Phase 1 40 participants

Simvastatin Metabolism as a Test for CD Activity (IRB 15-007568]

Entero Therapeutics

NCT03011931

COMPLETED NA 24 participants

T Cell Receptor (TCR) Sequencing and Transcriptional Profiling in Adult Celiac Disease Patients Undergoing Gluten Challenge

Regeneron Pharmaceuticals

NCT04614571

COMPLETED Phase 1 12 participants

PTG-100 for Patients With Celiac Disease

Nielsen Fernandez-Becker

NCT04524221

COMPLETED 12 participants

A Decentralized Home-Based Study To Investigate Novel Objective Biomarker Of Gluten-Mediated Symptoms In Celiac Disease Participants (CeDar ROSE Study)

Chugai Pharmaceutical

NCT05686369

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 6

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Celiac Disease Trial Landscape

25 indexed Celiac Disease studies · 14 recruiting (56%).

Phase mix: 0 late (III/IV) vs 10 early (I/II).

Top sponsor: Nielsen Fernandez-Becker (2 trials), 9 others listed. 25 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Celiac Disease?

PlainTrial tracks 25 US clinical trials for Celiac Disease, of which 14 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Celiac Disease?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.