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The Heartland Study
NCT05492708 · View on ClinicalTrials.gov ↗
Study Summary
The Heartland Study is a prospective, observational study that will enroll up to 2,600 pregnant participants across the Heartland States in the U.S.. The objective of the Heartland Study is to address major knowledge gaps concerning the health effects of herbicides on maternal and infant health. The study is being conducted to evaluate the associations between environmental exposures to herbicides during and after pregnancy and reproductive health outcomes. The study is measuring multiple biomarkers of herbicide exposure among pregnant Midwesterners and their partners to evaluate associations with pregnancy and childbirth outcomes, epigenetic biomarkers of exposure, and child development.
Conditions Studied
Study Locations (4)
Wisconsin
- Gundersen Health — La Crosse
- Marshfield Clinic — Marshfield
Indiana
- Indiana University Medical Center — Indianapolis
Iowa
- University of Iowa Health Care — Iowa City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,600 participants |
| Start Date | 2020-01-11 |
| Est. Completion | 2029-01 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05492708
The ClinicalTrials.gov registry entry for NCT05492708 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 2,600 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Heartland Health Research Alliance, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 7 conditions, with Pregnancy Related appearing as the primary indexed condition, and to 0 interventions. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05492708 reports 4 study locations spanning 3 distinct geographic areas — top geographies include Wisconsin, Indiana, Iowa. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05492708 about?
NCT05492708 is a clinical study titled "The Heartland Study". The Heartland Study is a prospective, observational study that will enroll up to 2,600 pregnant participants across the Heartland States in the U.S.. The objective of the Heartland Study is to address major knowledge gaps concerning the health effects of herbicides on maternal and infant health. Th...
What is the current status of trial NCT05492708?
This trial is currently recruiting. The enrollment target is 2,600 participants. The study started on 2020-01-11. Estimated completion is 2029-01.
What conditions does trial NCT05492708 study?
This clinical trial studies the following conditions: Pregnancy Related, Pregnancy Complications, Miscarriage, Birth Defect, Exposure to Herbicides. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
Who is sponsoring clinical trial NCT05492708?
This trial is sponsored by Heartland Health Research Alliance, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05492708 being conducted?
This trial has 4 study locations across Indiana, Iowa, Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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