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ClinicalTrials.gov 46 recruiting now later-stage tilt #112 of 28,707 conditions

Pain, Postoperative: later-stage trial registry

46 of 114 indexed Pain, Postoperative trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #112 of 28,707 conditions by registered trial count.

114 US clinical trials · 46 currently recruiting · #112 of 28,707 conditions by registered trial count

Pain, Postoperative: 114 US clinical trials tracked, 46 recruiting.

Pain, Postoperative is the subject of 114 registered US clinical trials on ClinicalTrials.gov, 46 of them currently open to new participants. 53 are in Phase 3-4 (later-stage) and 18 in Phase 1-2 (earlier-stage). The most active sponsor is University of Michigan, running 5 of these trials.

Enrollment posture brief

Registry condition pain-postoperative

OPEN 46 | RECR 40% | LATE 53 | EARLY 18 | RANK #112 | SPON 5

Nearest open-share peer: Quality of Life (40% recruiting · 109 trials)

Diffuse Large B Cell Lymphom46.1%Healthy Volunteer43.4%Pain, Postoperative (this)40%Osteoarthritis, Knee39.1%Type 1 Diabetes Mellitus22.1%
Open-enrollment share among volume-matched conditions near Pain, Postoperative

Pain, Postoperative lists 46 open slots (40% of 114 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Pain, Postoperative on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Pain, Postoperative is recruiting above its size-band peers.

    46 of 114 indexed trials (40.4%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Pain, Postoperative trials is spread across many organizations.

    University of Michigan accounts for 5 of 114 trials (4.4%). 78 distinct sponsors appear on at least one study for this condition label.

  3. Typical Pain, Postoperative enrolment sits around 80 participants.

    Median target enrolment is 80 among the 114 trials that report a genuine target (sentinel values excluded). 67 of those (58.8%) plan for fewer than 100 participants.

  4. Pain, Postoperative research is mostly interventional.

    110 interventional and 4 observational studies make up this index (96.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 17Phase 211Phase 315Phase 438

Open and recent trials

114 total, page 3 of 3

COMPLETED Phase 1 52 participants

The Effect Of An Anesthetic Procedure On Post Operative Pain Management In Carpal Tunnel Release

University of South Florida

NCT03729375

COMPLETED Phase 3 51 participants

Study of Oral Morphine Sulfate Administration in Pediatric Subjects

West-Ward Pharmaceutical

NCT03429400

COMPLETED Phase 4 50 participants

Post-Op Lidocaine Patch

Oregon Health and Science University

NCT03500211

COMPLETED Phase 3 50 participants

Management of Post-Tonsillectomy Pain in Pediatric Patients

Washington University School of Medicine

NCT04551196

COMPLETED Phase 3 41 participants

Para-cervical Block Prior to Laparoscopic Hysterectomy as an Adjuvant Treatment to Reduce Postoperative Pain.

University of Tennessee

NCT03027661

COMPLETED NA 40 participants

Virtual Reality in the Operating Room

Beth Israel Deaconess Medical Center

NCT03614325

COMPLETED NA 36 participants

Topical Proparacaine Eye Drops to Improve the Experience of Patients Undergoing Intravitreal Injections

Mayo Clinic

NCT02951351

COMPLETED NA 36 participants

Online Mindfulness-based Intervention to Prevent Chronic Pain

Florida State University

NCT04848428

COMPLETED NA 32 participants

Utilization of Different Virtual Reality Experiences

Oregon Health and Science University

NCT04828980

COMPLETED Phase 2 30 participants

Oxidative Stress and Surgical Recovery

Stanford University

NCT04732000

COMPLETED NA 24 participants

Erector Spinae Plane Blocks for Adolescent Idiopathic Scoliosis

Hospital for Special Surgery, New York

NCT04500613

COMPLETED Phase 3 10 participants

Bilateral Continuous Erector Spinae Blocks for Post-Sternotomy Pain Management: A Pilot Study

Boston Children's Hospital

NCT03936387

COMPLETED NA 10 participants

Effect of Using Placental Membranes on Healing and Post-op Pain After Gum Surgery

Harvard Medical School (HMS and HSDM)

NCT04957342

COMPLETED Phase 4 10 participants

Sub-Paraspinal Block in Nuss Patients. A Pilot Project

Nemours Children's Clinic

NCT02169297

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Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 11
Phase 3 15
Phase 4 38

Named interventions

Most-linked intervention names on Pain, Postoperative records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
10 trials
Acetaminophen Drug
6 trials
Bupivacaine Drug
5 trials
Gabapentin Drug
3 trials
Exparel Drug
3 trials
Liposomal bupivacaine Drug
3 trials
Methadone Drug
3 trials
Placebo Other
3 trials

US sites by state

Facility locations filed on Pain, Postoperative trials. A trial with sites in several states counts in each.

California 28 trials
Massachusetts 12 trials
Texas 11 trials
Pennsylvania 11 trials
New York 9 trials
North Carolina 8 trials
Missouri 8 trials
Michigan 7 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Pain, Postoperative page

114 registered trials, 46 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Pain, Postoperative condition card totals 114 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.