Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Quality of Life
Open-data reference.
109 US clinical trials · 44 currently recruiting
Active & Recent Trials
Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial
Washington University School of Medicine
NCT05991453
The Lake Nona Life Project
University of Central Florida
NCT02533804
Embedded Palliative Care in the MICU
Washington University School of Medicine
NCT06574672
M2VA Pain Care Pathway
Yale University
NCT06526143
Quality of Life and Life Satisfaction in Pediatric and Adolescent Gymnasts Through Injury
University of Colorado, Denver
NCT05110729
A Cardiac Disease Quality of Life Study
The Cleveland Clinic
NCT04080492
International CIPN Assessment and Validation Study
University of Milano Bicocca
NCT04633655
Improving Congenital Heart Disease Care
University of California, San Francis
NCT06581484
Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)
VA Office of Research and Development
NCT04179981
Together After Cancer
University of South Florida
NCT05645471
CAPABLE Care + Connect
Johns Hopkins University
NCT07123298
Project HOPEFUL: A PN-RCT With Implementation Science
University of Florida
NCT07475039
Improving Behavioral Health for Caregivers and Children After Pediatric Injury
Medical University of South Carolina
NCT06856057
Mobile Health Program for Rural Hypertension
University of Pittsburgh
NCT05546931
Expanded Population Health Model Evaluation
Baylor Research Institute
NCT06044831
OPtimizing Technology to Improve Medication Adherence and BP Control (OPTIMA-BP)
Case Western Reserve University
NCT05293756
The Student Wellness and Emotional Growth Resiliency (SWAG-R) Program
Nova Southeastern University
NCT06652503
Breast Cancer - Navigate - Prospective Cohort
Northwestern University
NCT06271356
Mindfulness in Endometrial and Cervical Cancer
St. Louis University
NCT04512144
Survivorship Care for Women Living With Ovarian Cancer: (POSTCARE-O)
Baylor College of Medicine
NCT05752448
Assessing the Effectiveness of Digital Wellness Modules on Perceived Quality of Life
Yale University
NCT05810259
Effect of a Fermented Dairy Protein With Prebiotic Fiber on GI Complaints
Arizona State University
NCT06946017
Improving Exercise Capacity With a Tailored Physical Activity Intervention
Wake Forest University Health Sciences
NCT05595577
Therapeutic Plantar Electrical Stimulation Intervention During Hemodialysis to Improve Balance and Mobility
Hamad Medical Corporation
NCT05407207
Effect of Drain Care on Infection Rate and Quality of Life in Implant-Based Breast Reconstruction.
University of Missouri-Columbia
NCT05846438
Effects of Assisted Robotic vs Laparoscopic Sleeve Gastrectomy
Ricard Corcelles
NCT06425016
Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After Lumpectomy
UNC Lineberger Comprehensive Cancer Center
NCT05472792
PODER Familiar: Health Promotion for Latino Families of Children With IDD
University of Texas at Austin
NCT05713617
Asthma Intervention With Residential Ventilation and Air Cleaner (AIRVAC) Study
The University of Texas at Arlington
NCT07196436
Developing a Smartphone Application to Support Veteran Opioid Use Disorder Treatment
VA Office of Research and Development
NCT06454903
The RolE of Prolonged Nightly faSTing to Improve Sleep and cOgnition in bREast Cancer Survivors
Arizona State University
NCT06938555
Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor
Vanderbilt University Medical Center
NCT01734122
Telehealth to Improve Quality of Life in Persons Living in Rural Texas
Texas Tech University
NCT07119710
Preemptive Ibuprofen Effects on Pain Perception Following Extraction and Bone Graft
Marquette University
NCT05919745
A rTMS and Virtual Reality Based Cognitive Rehabilitation Program for MCI
Central Arkansas Veterans Healthcare System
NCT06024473
The PREGNANT (Pregnant Resident Empowerment, GuidaNce, and Advocacy iN Training) Coaching Project
Massachusetts General Hospital
NCT07221422
CAPABLE Transplant
Johns Hopkins University
NCT06326905
Pain Intervention With Needling: Pilot Of Integrated Neuromodulation Techniques
The University of Texas Medical Branch, Galveston
NCT07112404
Exploring Virtual Reality Adventure Training Exergaming
The University of Texas at Arlington
NCT05563805
Development of a Multi-sensory Rehabilitation Program for People With Ultra Low Vision
State University of New York College of Optometry
NCT05028712
Quality of Life in Pediatric Patients With Acute Lymphoblastic Leukemia Receiving Maintenance Chemotherapy
Connecticut Children's Medical Center
NCT03132948
Effects of an Exercise Program on Reaction Time and Mouse Accuracy in Recreational Video Game Players
University of Miami
NCT06512675
Climbing Lifestyle Intervention for Modifying Physical Activity Behaviors: Pilot Study
Northern Michigan University
NCT06368128
Standardized Yoga & Meditation Program for Stress Reduction for Adolescents With Irritable Bowel Syndrome
The Cooper Health System
NCT05719246
Clinic-Based Financial Coaching and Family Health and Development
University of California, Los Angeles
NCT03736590
Efficacy of a Self-advocacy Serious Game Intervention
University of Pittsburgh
NCT04813276
Peer Approaches to Lupus Self-management
Medical University of South Carolina
NCT03734055
Roadmap to Parenthood: Testing the Efficacy of a Decision Aid and Planning Tool for Family Building After Cancer
Stanford University
NCT06050135
Guaranteed Income and Financial Treatment
Meredith Doherty, PhD, LCSW
NCT06611982
Ostomy Rural Telehealth Training Cancer Survivors
Abramson Cancer Center at Penn Medicine
NCT03913715
Invest-CTO PCI Trial
Haukeland University Hospital
NCT04774913
Long Term Follow up of Children Enrolled in the REDvent Study
Children's Hospital Los Angeles
NCT03709199
Multidisciplinary Intervention In Chronic GVHD
Massachusetts General Hospital
NCT04479995
Digital Symptom Tracking, Patient Engagement and Quality of Life in Advanced Cancer
Stanford University
NCT05112198
Bright IDEAS for Pediatric Palliative Care: A Problem-Solving Skills Intervention to Empower Parent Resilience
Children's Hospital Los Angeles
NCT05899998
Novel Respiratory Training as Part of Palliative Care for Older Adults With Heart Failure
University of Pittsburgh
NCT06576297
Horizons Chronic Graft-Versus-Host-Disease Study
University of Miami
NCT06160986
Digital Health Intervention to Promote Quality of Life in Adults With Chronic Graft Versus Host Disease
University of Miami
NCT06688942
Digital Literacy Intervention to Address Support, Literacy and Communication in Older Adults
Johns Hopkins University
NCT06479707
Impact of Different Carbohydrate Feedings on a Hydrogen Breath Curve and Self-reported Gastrointestinal Complaints
Arizona State University
NCT06648967
Safety and Feasibility of Polychromatic Light Emitting Diode for Peripheral Catheter Illumination During Peripheral Intravenous Delivery of Normal Saline
UVLrx Therapeutics
NCT02785133
The BE WITH Project: A Partially Nested Randomized Control Trial (PN-RCT)
University of Florida
NCT07204444
Symptom Screening Linked to Care Pathways
The Hospital for Sick Children
NCT04614662
Impact of Teledermatology on Health Services Outcomes in the Department of Veterans Affairs
US Department of Veterans Affairs
NCT00488293
Implementation of Multidisciplinary Assessments for Geriatric Patients in an ED Observation Unit
Ohio State University
NCT04068311
A Trial of an Integrated Clinic-community Intervention in Children and Adolescents With Obesity (Hearts and Parks)
Duke University
NCT03339440
Multilevel Intervention for Physical Activity in Retirement Communities
University of California, San Diego
NCT01155011
Comprehensive Care of Children With Medical Complexity
Seton Healthcare Family
NCT01834456
Sunshine 2 Study for Women With Diabetes
Loyola University
NCT01904032
Prostate Cancer: Family Care for Patients and Spouses
University of Michigan
NCT00708968
Quality of Life and Pain Outcomes Following Video-Assisted Thoracic Surgery (VATS) Anatomic Lung Resection Versus Thoracotomy and Anatomic Lung Resection
Memorial Sloan Kettering Cancer Center
NCT00598000
The In4M Study: Integrating 4 Methods to Assess Physical Function in Cancer Patients
Yale University
NCT05214144
Active Recreation Through Community-Healthcare Engagement Study
Duke University
NCT03246763
Technology and Family Thriving Study
University of California, Santa Barbara
NCT05150990
Blue Star Cares: Innovative Approaches to Helping Military-Connected Caregivers
University of Southern California
NCT03336190
FitEx for Endometrial Cancer Survivors: Initial Efficacy
Carilion Clinic
NCT05737745
An Exploratory Investigation of Dietary Supplementation and Its Effect
HUM Nutrition
NCT05037877
The PediQUEST Study: Evaluation of Pediatric Quality of Life and Evaluation of Symptoms Technology
Dana-Farber Cancer Institute
NCT01838564
Protein-Prebiotic Wellbeing Study
Arizona State University
NCT05303753
The "PC-LIGHT" Study
Northwestern University
NCT03419585
CAPABLE Family Pilot - Adapting CAPABLE for Older Adults With Mild Cognitive Impairment (MCI)/Early Stage Dementia and Their Care Partners
Johns Hopkins University
NCT05187117
Stepped-Care Telehealth for Distress in Cancer Survivors
Wake Forest University Health Sciences
NCT03060096
Effects of Arts Engagement on Physical Performance, Cognition, Social Isolation, and Self-Perception in Older Adults
George Mason University
NCT04281654
Improving Supportive Care For Patients With Thoracic Malignancies
Palo Alto Veterans Institute for Research
NCT03216109
Treating Cancer-Related Fatigue Through Systematic Light Exposure
Icahn School of Medicine at Mount Sinai
NCT01873794
Effects of a Proactive Social Robot for Older Adults in Reducing Loneliness and Social Isolation
Baycrest
NCT03972787
Internet and Telephone Support Intervention for Stroke Caregivers
VA Office of Research and Development
NCT04348851
Mindful Kala: Virtual Bharatanatyam Wellness Program for Students
Yale University
NCT04745364
Focused Palliative Care Intervention in Advanced Heart Failure
Brigham and Women's Hospital
NCT02805712
Pediatric Dysphagia Outcomes After Injection Laryngoplasty for Type I Laryngeal Cleft
Oregon Health and Science University
NCT01507207
Physical Therapy on Quality of Life and Function Following Vaginal Surgery Reconstructive Surgery
TriHealth
NCT01403701
Neuromodulation of Central Sensory Integration to Improve Postural Control
University of Pittsburgh
NCT06610617
Computerized Cognitive Training in Breast Cancer Survivors
Ohio State University
NCT05570604
Effects of a Community Based Exercise Program in Adults With Severe Burns
The University of Texas Medical Branch, Galveston
NCT01184547
Laser Ablation After Stereotactic Radiosurgery
Monteris Medical
NCT01651078
Long-Term Effects of Iodine I Tositumomab and Autologous Bone Marrow or Stem Cell Transplantation in Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Fred Hutchinson Cancer Center
NCT00098566
Effectiveness of 10-minute Chair Massage Versus 10-minute Break to Reduce Stress and Improve Well-being
Geisinger Clinic
NCT04787107
Intervention Development and Evaluation to Reduce Disparities in Quality of Life for Latino Families Impacted by Cancer
University of California, Irvine
NCT06622252
High-Speed Yoga and Executive Function
University of Miami
NCT04215900
Improving Care of Patients With Heart Failure
University of California, San Francis
NCT01461681
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 1 |
| Phase 2 | 3 |
| Phase 3 | 1 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Quality of Life Trial Landscape
ClinicalTrials.gov lists 109 US studies indexed under Quality of Life, and 44 of those are currently open to recruitment — roughly 40% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Quality of Life shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Quality of Life is led by Arizona State University with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 100 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Quality of Life?
PlainTrial tracks 109 US clinical trials for Quality of Life, of which 44 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Quality of Life?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.