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ClinicalTrials.gov 44 recruiting now full pipeline #117 of 28,707 conditions

Quality of Life: full-pipeline trial registry

44 of 109 indexed Quality of Life trials are currently recruiting.

Corpus placement: #117 of 28,707 conditions by registered trial count.

109 US clinical trials · 44 currently recruiting · #117 of 28,707 conditions by registered trial count

Quality of Life: 109 US clinical trials tracked, 44 recruiting.

Quality of Life is the subject of 109 registered US clinical trials on ClinicalTrials.gov, 44 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Arizona State University, running 4 of these trials.

Enrollment posture brief

Registry condition quality-of-life

OPEN 44 | RECR 40% | LATE 3 | EARLY 4 | RANK #117 | SPON 4

Nearest open-share peer: Pain, Postoperative (40% recruiting · 114 trials)

Breast Carcinoma58.9%Quality of Life (this)40%Fatigue30%Advanced Malignant Solid Neo24.8%Hepatitis C12%
Open-enrollment share among volume-matched conditions near Quality of Life

Quality of Life lists 44 open slots (40% of 109 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Quality of Life on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Quality of Life is recruiting above its size-band peers.

    44 of 109 indexed trials (40.4%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Quality of Life trials is spread across many organizations.

    Arizona State University accounts for 4 of 109 trials (3.7%). 77 distinct sponsors appear on at least one study for this condition label.

  3. Typical Quality of Life enrolment sits around 90 participants.

    Median target enrolment is 90 among the 108 trials that report a genuine target (sentinel values excluded). 57 of those (52.8%) plan for fewer than 100 participants.

  4. Quality of Life research is mostly interventional.

    98 interventional and 11 observational studies make up this index (89.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 23Phase 31Phase 42

Open and recent trials

109 total, page 1 of 3

RECRUITING NA 13,000 participants

Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial

Washington University School of Medicine

NCT05991453

RECRUITING 10,000 participants

The Lake Nona Life Project

University of Central Florida

NCT02533804

RECRUITING NA 2,600 participants

Embedded Palliative Care in the MICU

Washington University School of Medicine

NCT06574672

RECRUITING NA 1,800 participants

M2VA Pain Care Pathway

Yale University

NCT06526143

RECRUITING 1,218 participants

Quality of Life and Life Satisfaction in Pediatric and Adolescent Gymnasts Through Injury

University of Colorado, Denver

NCT05110729

RECRUITING 1,200 participants

A Cardiac Disease Quality of Life Study

The Cleveland Clinic

NCT04080492

RECRUITING 1,000 participants

International CIPN Assessment and Validation Study

University of Milano Bicocca

NCT04633655

RECRUITING NA 1,000 participants

Improving Congenital Heart Disease Care

University of California, San Francisco

NCT06581484

RECRUITING NA 668 participants

Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)

VA Office of Research and Development

NCT04179981

RECRUITING NA 480 participants

Together After Cancer

University of South Florida

NCT05645471

RECRUITING NA 450 participants

CAPABLE Care + Connect

Johns Hopkins University

NCT07123298

RECRUITING NA 400 participants

Project HOPEFUL: A PN-RCT With Implementation Science

University of Florida

NCT07475039

RECRUITING NA 348 participants

Improving Behavioral Health for Caregivers and Children After Pediatric Injury

Medical University of South Carolina

NCT06856057

RECRUITING NA 334 participants

Mobile Health Program for Rural Hypertension

University of Pittsburgh

NCT05546931

RECRUITING 300 participants

Expanded Population Health Model Evaluation

Baylor Research Institute

NCT06044831

RECRUITING NA 208 participants

OPtimizing Technology to Improve Medication Adherence and BP Control (OPTIMA-BP)

Case Western Reserve University

NCT05293756

RECRUITING NA 160 participants

The Student Wellness and Emotional Growth Resiliency (SWAG-R) Program

Nova Southeastern University

NCT06652503

RECRUITING NA 150 participants

Breast Cancer - Navigate - Prospective Cohort

Northwestern University

NCT06271356

RECRUITING NA 120 participants

Mindfulness in Endometrial and Cervical Cancer

St. Louis University

NCT04512144

RECRUITING NA 120 participants

Survivorship Care for Women Living With Ovarian Cancer: (POSTCARE-O)

Baylor College of Medicine

NCT05752448

RECRUITING NA 120 participants

Assessing the Effectiveness of Digital Wellness Modules on Perceived Quality of Life

Yale University

NCT05810259

RECRUITING NA 114 participants

Effect of a Fermented Dairy Protein With Prebiotic Fiber on GI Complaints

Arizona State University

NCT06946017

RECRUITING NA 110 participants

Improving Exercise Capacity With a Tailored Physical Activity Intervention

Wake Forest University Health Sciences

NCT05595577

RECRUITING NA 100 participants

Therapeutic Plantar Electrical Stimulation Intervention During Hemodialysis to Improve Balance and Mobility

Hamad Medical Corporation

NCT05407207

RECRUITING NA 100 participants

Effect of Drain Care on Infection Rate and Quality of Life in Implant-Based Breast Reconstruction.

University of Missouri-Columbia

NCT05846438

RECRUITING NA 91 participants

Effects of Assisted Robotic vs Laparoscopic Sleeve Gastrectomy

Ricard Corcelles

NCT06425016

RECRUITING Phase 2 90 participants

Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After Lumpectomy

UNC Lineberger Comprehensive Cancer Center

NCT05472792

RECRUITING NA 90 participants

PODER Familiar: Health Promotion for Latino Families of Children With IDD

University of Texas at Austin

NCT05713617

RECRUITING NA 80 participants

Asthma Intervention With Residential Ventilation and Air Cleaner (AIRVAC) Study

The University of Texas at Arlington

NCT07196436

RECRUITING NA 75 participants

Developing a Smartphone Application to Support Veteran Opioid Use Disorder Treatment

VA Office of Research and Development

NCT06454903

RECRUITING NA 60 participants

The RolE of Prolonged Nightly faSTing to Improve Sleep and cOgnition in bREast Cancer Survivors

Arizona State University

NCT06938555

RECRUITING 60 participants

Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor

Vanderbilt University Medical Center

NCT01734122

RECRUITING NA 60 participants

Telehealth to Improve Quality of Life in Persons Living in Rural Texas

Texas Tech University

NCT07119710

RECRUITING Phase 4 50 participants

Preemptive Ibuprofen Effects on Pain Perception Following Extraction and Bone Graft

Marquette University

NCT05919745

RECRUITING NA 50 participants

A rTMS and Virtual Reality Based Cognitive Rehabilitation Program for MCI

Central Arkansas Veterans Healthcare System

NCT06024473

RECRUITING NA 48 participants

The PREGNANT (Pregnant Resident Empowerment, GuidaNce, and Advocacy iN Training) Coaching Project

Massachusetts General Hospital

NCT07221422

RECRUITING NA 43 participants

CAPABLE Transplant

Johns Hopkins University

NCT06326905

RECRUITING NA 42 participants

Pain Intervention With Needling: Pilot Of Integrated Neuromodulation Techniques

The University of Texas Medical Branch, Galveston

NCT07112404

RECRUITING NA 40 participants

Exploring Virtual Reality Adventure Training Exergaming

The University of Texas at Arlington

NCT05563805

RECRUITING NA 36 participants

Development of a Multi-sensory Rehabilitation Program for People With Ultra Low Vision

State University of New York College of Optometry

NCT05028712

RECRUITING NA 25 participants

Quality of Life in Pediatric Patients With Acute Lymphoblastic Leukemia Receiving Maintenance Chemotherapy

Connecticut Children's Medical Center

NCT03132948

RECRUITING NA 15 participants

Effects of an Exercise Program on Reaction Time and Mouse Accuracy in Recreational Video Game Players

University of Miami

NCT06512675

RECRUITING NA 12 participants

Climbing Lifestyle Intervention for Modifying Physical Activity Behaviors: Pilot Study

Northern Michigan University

NCT06368128

RECRUITING NA 10 participants

Standardized Yoga & Meditation Program for Stress Reduction for Adolescents With Irritable Bowel Syndrome

The Cooper Health System

NCT05719246

ACTIVE NOT RECRUITING NA 400 participants

Clinic-Based Financial Coaching and Family Health and Development

University of California, Los Angeles

NCT03736590

ACTIVE NOT RECRUITING Phase 2 336 participants

Efficacy of a Self-advocacy Serious Game Intervention

University of Pittsburgh

NCT04813276

ACTIVE NOT RECRUITING NA 314 participants

Peer Approaches to Lupus Self-management

Medical University of South Carolina

NCT03734055

ACTIVE NOT RECRUITING NA 260 participants

Roadmap to Parenthood: Testing the Efficacy of a Decision Aid and Planning Tool for Family Building After Cancer

Stanford University

NCT06050135

ACTIVE NOT RECRUITING NA 250 participants

Guaranteed Income and Financial Treatment

Meredith Doherty, PhD, LCSW

NCT06611982

ACTIVE NOT RECRUITING NA 204 participants

Ostomy Rural Telehealth Training Cancer Survivors

Abramson Cancer Center at Penn Medicine

NCT03913715

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Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 3
Phase 3 1
Phase 4 2

Named interventions

Most-linked intervention names on Quality of Life records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Peer Mentoring Behavioral
2 trials
Physical Activity Behavioral
2 trials
Placebo Dietary supplement
2 trials
Enhanced Usual Care Control Other
1 trials
Moderate Anxiety/depression: Low Intensity Stepped care Other
1 trials
Severe Anxiety/depression: High Intensity Stepped Care Other
1 trials
avatar-based training Behavioral
1 trials
FOCUS Program Behavioral
1 trials

US sites by state

Facility locations filed on Quality of Life trials. A trial with sites in several states counts in each.

California 18 trials
Texas 14 trials
Florida 13 trials
Pennsylvania 11 trials
New York 10 trials
Connecticut 9 trials
Ohio 7 trials
North Carolina 7 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Quality of Life page

109 registered trials, 44 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Quality of Life condition card totals 109 registered trials; most-linked intervention Peer Mentoring; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.