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ClinicalTrials.gov 44 recruiting now official registry

Quality of Life clinical trials

44 of 109 indexed Quality of Life trials are currently recruiting.

109 US clinical trials · 44 currently recruiting

Quality of Life is the subject of 109 registered US clinical trials on ClinicalTrials.gov, 44 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Arizona State University, running 4 of these trials.

The research picture

Quality of Life has 109 registered US clinical trials, 44 of them open to new participants right now, about 40% of the total.

44
recruiting participants now
40%
of trials open to enrollment
3
in Phase 3–4 (later-stage)
4
top sponsor: Arizona State University
Phase 11Phase 23Phase 31Phase 42

Active & Recent Trials

109 total, page 1 of 3

RECRUITING NA 13,000 participants

Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial

Washington University School of Medicine

NCT05991453

RECRUITING 10,000 participants

The Lake Nona Life Project

University of Central Florida

NCT02533804

RECRUITING NA 2,600 participants

Embedded Palliative Care in the MICU

Washington University School of Medicine

NCT06574672

RECRUITING NA 1,800 participants

M2VA Pain Care Pathway

Yale University

NCT06526143

RECRUITING 1,218 participants

Quality of Life and Life Satisfaction in Pediatric and Adolescent Gymnasts Through Injury

University of Colorado, Denver

NCT05110729

RECRUITING 1,200 participants

A Cardiac Disease Quality of Life Study

The Cleveland Clinic

NCT04080492

RECRUITING 1,000 participants

International CIPN Assessment and Validation Study

University of Milano Bicocca

NCT04633655

RECRUITING NA 1,000 participants

Improving Congenital Heart Disease Care

University of California, San Francisco

NCT06581484

RECRUITING NA 668 participants

Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)

VA Office of Research and Development

NCT04179981

RECRUITING NA 480 participants

Together After Cancer

University of South Florida

NCT05645471

RECRUITING NA 450 participants

CAPABLE Care + Connect

Johns Hopkins University

NCT07123298

RECRUITING NA 400 participants

Project HOPEFUL: A PN-RCT With Implementation Science

University of Florida

NCT07475039

RECRUITING NA 348 participants

Improving Behavioral Health for Caregivers and Children After Pediatric Injury

Medical University of South Carolina

NCT06856057

RECRUITING NA 334 participants

Mobile Health Program for Rural Hypertension

University of Pittsburgh

NCT05546931

RECRUITING 300 participants

Expanded Population Health Model Evaluation

Baylor Research Institute

NCT06044831

RECRUITING NA 208 participants

OPtimizing Technology to Improve Medication Adherence and BP Control (OPTIMA-BP)

Case Western Reserve University

NCT05293756

RECRUITING NA 160 participants

The Student Wellness and Emotional Growth Resiliency (SWAG-R) Program

Nova Southeastern University

NCT06652503

RECRUITING NA 150 participants

Breast Cancer - Navigate - Prospective Cohort

Northwestern University

NCT06271356

RECRUITING NA 120 participants

Mindfulness in Endometrial and Cervical Cancer

St. Louis University

NCT04512144

RECRUITING NA 120 participants

Survivorship Care for Women Living With Ovarian Cancer: (POSTCARE-O)

Baylor College of Medicine

NCT05752448

RECRUITING NA 120 participants

Assessing the Effectiveness of Digital Wellness Modules on Perceived Quality of Life

Yale University

NCT05810259

RECRUITING NA 114 participants

Effect of a Fermented Dairy Protein With Prebiotic Fiber on GI Complaints

Arizona State University

NCT06946017

RECRUITING NA 110 participants

Improving Exercise Capacity With a Tailored Physical Activity Intervention

Wake Forest University Health Sciences

NCT05595577

RECRUITING NA 100 participants

Therapeutic Plantar Electrical Stimulation Intervention During Hemodialysis to Improve Balance and Mobility

Hamad Medical Corporation

NCT05407207

RECRUITING NA 100 participants

Effect of Drain Care on Infection Rate and Quality of Life in Implant-Based Breast Reconstruction.

University of Missouri-Columbia

NCT05846438

RECRUITING NA 91 participants

Effects of Assisted Robotic vs Laparoscopic Sleeve Gastrectomy

Ricard Corcelles

NCT06425016

RECRUITING Phase 2 90 participants

Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After Lumpectomy

UNC Lineberger Comprehensive Cancer Center

NCT05472792

RECRUITING NA 90 participants

PODER Familiar: Health Promotion for Latino Families of Children With IDD

University of Texas at Austin

NCT05713617

RECRUITING NA 80 participants

Asthma Intervention With Residential Ventilation and Air Cleaner (AIRVAC) Study

The University of Texas at Arlington

NCT07196436

RECRUITING NA 75 participants

Developing a Smartphone Application to Support Veteran Opioid Use Disorder Treatment

VA Office of Research and Development

NCT06454903

RECRUITING NA 60 participants

The RolE of Prolonged Nightly faSTing to Improve Sleep and cOgnition in bREast Cancer Survivors

Arizona State University

NCT06938555

RECRUITING 60 participants

Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor

Vanderbilt University Medical Center

NCT01734122

RECRUITING NA 60 participants

Telehealth to Improve Quality of Life in Persons Living in Rural Texas

Texas Tech University

NCT07119710

RECRUITING Phase 4 50 participants

Preemptive Ibuprofen Effects on Pain Perception Following Extraction and Bone Graft

Marquette University

NCT05919745

RECRUITING NA 50 participants

A rTMS and Virtual Reality Based Cognitive Rehabilitation Program for MCI

Central Arkansas Veterans Healthcare System

NCT06024473

RECRUITING NA 48 participants

The PREGNANT (Pregnant Resident Empowerment, GuidaNce, and Advocacy iN Training) Coaching Project

Massachusetts General Hospital

NCT07221422

RECRUITING NA 43 participants

CAPABLE Transplant

Johns Hopkins University

NCT06326905

RECRUITING NA 42 participants

Pain Intervention With Needling: Pilot Of Integrated Neuromodulation Techniques

The University of Texas Medical Branch, Galveston

NCT07112404

RECRUITING NA 40 participants

Exploring Virtual Reality Adventure Training Exergaming

The University of Texas at Arlington

NCT05563805

RECRUITING NA 36 participants

Development of a Multi-sensory Rehabilitation Program for People With Ultra Low Vision

State University of New York College of Optometry

NCT05028712

RECRUITING NA 25 participants

Quality of Life in Pediatric Patients With Acute Lymphoblastic Leukemia Receiving Maintenance Chemotherapy

Connecticut Children's Medical Center

NCT03132948

RECRUITING NA 15 participants

Effects of an Exercise Program on Reaction Time and Mouse Accuracy in Recreational Video Game Players

University of Miami

NCT06512675

RECRUITING NA 12 participants

Climbing Lifestyle Intervention for Modifying Physical Activity Behaviors: Pilot Study

Northern Michigan University

NCT06368128

RECRUITING NA 10 participants

Standardized Yoga & Meditation Program for Stress Reduction for Adolescents With Irritable Bowel Syndrome

The Cooper Health System

NCT05719246

ACTIVE NOT RECRUITING NA 400 participants

Clinic-Based Financial Coaching and Family Health and Development

University of California, Los Angeles

NCT03736590

ACTIVE NOT RECRUITING Phase 2 336 participants

Efficacy of a Self-advocacy Serious Game Intervention

University of Pittsburgh

NCT04813276

ACTIVE NOT RECRUITING NA 314 participants

Peer Approaches to Lupus Self-management

Medical University of South Carolina

NCT03734055

ACTIVE NOT RECRUITING NA 260 participants

Roadmap to Parenthood: Testing the Efficacy of a Decision Aid and Planning Tool for Family Building After Cancer

Stanford University

NCT06050135

ACTIVE NOT RECRUITING NA 250 participants

Guaranteed Income and Financial Treatment

Meredith Doherty, PhD, LCSW

NCT06611982

ACTIVE NOT RECRUITING NA 204 participants

Ostomy Rural Telehealth Training Cancer Survivors

Abramson Cancer Center at Penn Medicine

NCT03913715

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Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 3
Phase 3 1
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Quality of Life Trial Landscape

109 indexed Quality of Life studies · 44 recruiting (40%).

Phase mix: 3 late (III/IV) vs 4 early (I/II).

Top sponsor: Arizona State University (4 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Quality of Life?

PlainTrial tracks 109 US clinical trials for Quality of Life, of which 44 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Quality of Life?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.