Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Overweight clinical trials
50 of 198 indexed Overweight trials are currently recruiting.
198 US clinical trials · 50 currently recruiting
Overweight is the subject of 198 registered US clinical trials on ClinicalTrials.gov, 50 of them currently open to new participants. 37 are in Phase 3-4 (later-stage) and 46 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 37 of these trials.
The research picture
Overweight has 198 registered US clinical trials, 50 of them open to new participants right now, about 25% of the total.
- 50
- recruiting participants now
- 25%
- of trials open to enrollment
- 37
- in Phase 3–4 (later-stage)
- 37
- top sponsor: Eli Lilly and Company
Active & Recent Trials
198 total, page 4 of 4
Improving Mental Health in Youth and Lowering Risk for Obesity Through a Digital Preventative Product
Ksana Health
NCT05638516
Feasibility of a Partnered Approach to Prevent Diabetes
Northwestern University
NCT00302055
Impact of Weight Loss Interventions for Overweight Breast Cancer Survivors
University of Vermont
NCT01482702
Effect of Soy Protein and Colorado Diet on Weight Loss and Maintenance
DuPont Nutrition and Health
NCT02380963
Fit and Trim for Diabetes Prevention
University of California, San Francisco
NCT02278939
mDiet - Ecological Momentary Intervention of Diet Via Mobile Technology
University of California, San Diego
NCT00415870
Safety, Tolerability, Kinetics and Efficacy Study of Hoodia Gordonii Purified Extract (PYM50717)
Unilever R&D
NCT01306422
A System for Preference Assessment in Mental Health
University of California, Los Angeles
NCT02183844
Web-Based Weight Management for Individuals With Mental Illness
University of California, Los Angeles
NCT01324973
Brief Behavioral Weight Loss Treatment vs. Weight Watchers
The Miriam Hospital
NCT00249340
OA Clinic-Community CARE Model
University of North Carolina, Chapel Hill
NCT05349500
Mindfulness Training to Promote Healthy Diet and Physical Activity in Teens
University of Massachusetts, Worcester
NCT01975896
Gender- and Culturally-Sensitive Weight Loss Intervention for Hispanic Males
University of Arizona
NCT02783521
First-in-human Study to Assess Safety and Tolerability of a Single Subcutaneous Dose of SAR441255 in Lean to Overweight Subjects
Sanofi
NCT04521738
Targeting Body Image Among Women of Higher Body Weight
The Miriam Hospital
NCT04810247
T-helper 2 (Th2) Cytokine Responses in Overweight/Obese Subjects
West Penn Allegheny Health System
NCT02085759
Ultrasound Assessment of Rheumatoid Arthritis Patients Who Changed Diet
Veena Ranganath, MD, MS
NCT02881307
Feasibility Study of Receiving Feedback Messages Based on Self-monitored Dietary Intake
University of Pittsburgh
NCT02829632
Sedentary Behavior in Overweight Women
University of Mississippi Medical Center
NCT00613353
Nutrition, Exercise, and Technology for Weight Loss
University of South Carolina
NCT02731768
Impact of Eating Beans on Metabolism
USDA Grand Forks Human Nutrition Research Center
NCT06123208
CHOICES: Family Physicians Treat Overweight Children
University of Arizona
NCT01674920
Ignite Pilot: Goal Setting in a Digital Weight Loss Intervention
Stanford University
NCT05715242
Trial of Leptin Administration After Roux-en-Y Gastric Bypass
Columbia University
NCT00710814
Individualized Diet Improvement Program for Weight Loss and Maintenance, Cohort 2
University of Illinois at Urbana-Champaign
NCT04605640
Contingency Management to Promote Weight Loss in Low Income Adults
UConn Health
NCT00875199
Exercise and Weight Control
USDA Grand Forks Human Nutrition Research Center
NCT02152501
Mitochondrial Methylation in Type 2 Diabetes
University of Arizona
NCT04126551
Weight Bearing Exercise in Preventing Frailty in Stage I-IIIA Breast Cancer Survivors
University of Arizona
NCT03708055
Impact of Almond Supplementation on Body Composition in Overweight/Obese Minority Adults
Columbia University
NCT02347007
Women's Lifestyle Balance Study
University of California, San Francisco
NCT03184337
Fruit And Vegetable Or Recreation Prescriptions for UW-Madison Students
University of Wisconsin, Madison
NCT02870322
the Effectiveness of a Weight Management Program in Patients Who Have Completed Treatment for Endometrial Cancer
Sanford Health
NCT03908996
Glucose Tolerance in Healthy Overweight Adults
Abbott Nutrition
NCT00974831
Nutrition and Soccer for Pediatric Overweight and Obesity
Leach Chiropractic Clinic
NCT00365651
Dietary Fat and High-Density Lipoprotein (HDL) Metabolism-Effect of Carbohydrate and Fat Intake
Brigham and Women's Hospital
NCT01399632
Addressing Emotional and Cognitive Factors in Behavioral Weight Loss Treatment
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00533052
Appetite and Exercise in Breast Cancer Survivors
University of Colorado, Denver
NCT04300478
Ability of a Tea Leaf Extracts Preparation to Slow Down Carbohydrate and Fat Absorption
NatureGen
NCT00262145
A Study to Compare Two Different Forms of PF-07081532 in Adults Who Are Overweight or Obese
Pfizer
NCT05677867
Impact of a Childhood Obesity Intervention for African American Families
University of California, Berkeley
NCT02044731
Child Care Wellness Study on Nutrition and Physical Activity
University of North Carolina, Chapel Hill
NCT01921842
Exercise and Nutrition Program in Improving Physical Activity and Dietary Behavior in Non-Active, Overweight, or Obese Latinas
OHSU Knight Cancer Institute
NCT03028935
PACE-CALL: A Weight Control Intervention for Survivors of Childhood Leukemia
University of California, San Diego
NCT01171599
Implementation of a Cardiometabolic Disease Staging System in Primary Care
University of Alabama at Birmingham
NCT04922294
Absorption and Metabolic Profiles of a Sugar-based Beverage
Clinical Nutrition Research Center, Illinois Institute of Technology
NCT02226250
The Effects of Leucine on Body Weight
Columbia University
NCT00683826
Timing of Meals for Weight Loss
The University of Tennessee, Knoxville
NCT02204735
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 21 |
| Phase 2 | 25 |
| Phase 3 | 36 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Overweight Trial Landscape
198 indexed Overweight studies · 50 recruiting (25%).
Phase mix: 37 late (III/IV) vs 46 early (I/II).
Top sponsor: Eli Lilly and Company (37 trials), 9 others listed. 48 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Overweight?
PlainTrial tracks 198 US clinical trials for Overweight, of which 50 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Overweight?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.