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ClinicalTrials.gov 50 recruiting now full pipeline #52 of 28,707 conditions

Overweight: full-pipeline trial registry

50 of 198 indexed Overweight trials are currently recruiting.

Corpus placement: #52 of 28,707 conditions by registered trial count.

198 US clinical trials · 50 currently recruiting · #52 of 28,707 conditions by registered trial count

Overweight: 198 US clinical trials tracked, 50 recruiting.

Overweight is the subject of 198 registered US clinical trials on ClinicalTrials.gov, 50 of them currently open to new participants. 37 are in Phase 3-4 (later-stage) and 46 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 37 of these trials.

Enrollment posture brief

Registry condition overweight

OPEN 50 | RECR 25% | LATE 37 | EARLY 46 | RANK #52 | SPON 37

Nearest open-share peer: Low Back Pain (25% recruiting · 123 trials)

Solid Tumor52.8%Type 1 Diabetes39.7%Glioblastoma39%Overweight (this)25%Rheumatoid Arthritis18.6%
Open-enrollment share among volume-matched conditions near Overweight

Overweight lists 50 open slots (25% of 198 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Overweight on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Overweight is recruiting below its size-band peers.

    50 of 198 indexed trials (25.3%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Overweight research.

    Eli Lilly and Company accounts for 37 of 198 trials (18.7%). 94 distinct sponsors appear on at least one study for this condition label.

  3. Typical Overweight enrolment sits around 120 participants.

    Median target enrolment is 120 among the 198 trials that report a genuine target (sentinel values excluded). 89 of those (44.9%) plan for fewer than 100 participants.

  4. Overweight research is mostly interventional.

    182 interventional and 16 observational studies make up this index (91.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 121Phase 225Phase 336Phase 41

Open and recent trials

198 total, page 4 of 4

COMPLETED NA 73 participants

Improving Mental Health in Youth and Lowering Risk for Obesity Through a Digital Preventative Product

Ksana Health

NCT05638516

COMPLETED NA 72 participants

Feasibility of a Partnered Approach to Prevent Diabetes

Northwestern University

NCT00302055

COMPLETED NA 72 participants

Impact of Weight Loss Interventions for Overweight Breast Cancer Survivors

University of Vermont

NCT01482702

COMPLETED NA 72 participants

Effect of Soy Protein and Colorado Diet on Weight Loss and Maintenance

DuPont Nutrition and Health

NCT02380963

COMPLETED NA 67 participants

Fit and Trim for Diabetes Prevention

University of California, San Francisco

NCT02278939

COMPLETED NA 65 participants

mDiet - Ecological Momentary Intervention of Diet Via Mobile Technology

University of California, San Diego

NCT00415870

COMPLETED NA 64 participants

Safety, Tolerability, Kinetics and Efficacy Study of Hoodia Gordonii Purified Extract (PYM50717)

Unilever R&D

NCT01306422

COMPLETED NA 61 participants

A System for Preference Assessment in Mental Health

University of California, Los Angeles

NCT02183844

COMPLETED NA 60 participants

Web-Based Weight Management for Individuals With Mental Illness

University of California, Los Angeles

NCT01324973

COMPLETED NA 60 participants

Brief Behavioral Weight Loss Treatment vs. Weight Watchers

The Miriam Hospital

NCT00249340

COMPLETED NA 60 participants

OA Clinic-Community CARE Model

University of North Carolina, Chapel Hill

NCT05349500

COMPLETED NA 53 participants

Mindfulness Training to Promote Healthy Diet and Physical Activity in Teens

University of Massachusetts, Worcester

NCT01975896

COMPLETED NA 50 participants

Gender- and Culturally-Sensitive Weight Loss Intervention for Hispanic Males

University of Arizona

NCT02783521

COMPLETED Phase 1 48 participants

First-in-human Study to Assess Safety and Tolerability of a Single Subcutaneous Dose of SAR441255 in Lean to Overweight Subjects

Sanofi

NCT04521738

COMPLETED NA 46 participants

Targeting Body Image Among Women of Higher Body Weight

The Miriam Hospital

NCT04810247

COMPLETED 46 participants

T-helper 2 (Th2) Cytokine Responses in Overweight/Obese Subjects

West Penn Allegheny Health System

NCT02085759

COMPLETED NA 40 participants

Ultrasound Assessment of Rheumatoid Arthritis Patients Who Changed Diet

Veena Ranganath, MD, MS

NCT02881307

COMPLETED NA 39 participants

Feasibility Study of Receiving Feedback Messages Based on Self-monitored Dietary Intake

University of Pittsburgh

NCT02829632

COMPLETED 38 participants

Sedentary Behavior in Overweight Women

University of Mississippi Medical Center

NCT00613353

COMPLETED NA 36 participants

Nutrition, Exercise, and Technology for Weight Loss

University of South Carolina

NCT02731768

COMPLETED NA 36 participants

Impact of Eating Beans on Metabolism

USDA Grand Forks Human Nutrition Research Center

NCT06123208

COMPLETED NA 35 participants

CHOICES: Family Physicians Treat Overweight Children

University of Arizona

NCT01674920

COMPLETED NA 32 participants

Ignite Pilot: Goal Setting in a Digital Weight Loss Intervention

Stanford University

NCT05715242

COMPLETED Phase 1 31 participants

Trial of Leptin Administration After Roux-en-Y Gastric Bypass

Columbia University

NCT00710814

COMPLETED NA 30 participants

Individualized Diet Improvement Program for Weight Loss and Maintenance, Cohort 2

University of Illinois at Urbana-Champaign

NCT04605640

COMPLETED Phase 2 30 participants

Contingency Management to Promote Weight Loss in Low Income Adults

UConn Health

NCT00875199

COMPLETED NA 29 participants

Exercise and Weight Control

USDA Grand Forks Human Nutrition Research Center

NCT02152501

COMPLETED 27 participants

Mitochondrial Methylation in Type 2 Diabetes

University of Arizona

NCT04126551

COMPLETED NA 27 participants

Weight Bearing Exercise in Preventing Frailty in Stage I-IIIA Breast Cancer Survivors

University of Arizona

NCT03708055

COMPLETED NA 26 participants

Impact of Almond Supplementation on Body Composition in Overweight/Obese Minority Adults

Columbia University

NCT02347007

COMPLETED NA 26 participants

Women's Lifestyle Balance Study

University of California, San Francisco

NCT03184337

COMPLETED NA 25 participants

Fruit And Vegetable Or Recreation Prescriptions for UW-Madison Students

University of Wisconsin, Madison

NCT02870322

COMPLETED NA 25 participants

the Effectiveness of a Weight Management Program in Patients Who Have Completed Treatment for Endometrial Cancer

Sanford Health

NCT03908996

COMPLETED Phase 2 24 participants

Glucose Tolerance in Healthy Overweight Adults

Abbott Nutrition

NCT00974831

COMPLETED Phase 1 22 participants

Nutrition and Soccer for Pediatric Overweight and Obesity

Leach Chiropractic Clinic

NCT00365651

COMPLETED NA 21 participants

Dietary Fat and High-Density Lipoprotein (HDL) Metabolism-Effect of Carbohydrate and Fat Intake

Brigham and Women's Hospital

NCT01399632

COMPLETED NA 21 participants

Addressing Emotional and Cognitive Factors in Behavioral Weight Loss Treatment

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00533052

COMPLETED NA 21 participants

Appetite and Exercise in Breast Cancer Survivors

University of Colorado, Denver

NCT04300478

COMPLETED Phase 1 20 participants

Ability of a Tea Leaf Extracts Preparation to Slow Down Carbohydrate and Fat Absorption

NatureGen

NCT00262145

COMPLETED Phase 1 20 participants

A Study to Compare Two Different Forms of PF-07081532 in Adults Who Are Overweight or Obese

Pfizer

NCT05677867

COMPLETED NA 19 participants

Impact of a Childhood Obesity Intervention for African American Families

University of California, Berkeley

NCT02044731

COMPLETED NA 18 participants

Child Care Wellness Study on Nutrition and Physical Activity

University of North Carolina, Chapel Hill

NCT01921842

COMPLETED NA 15 participants

Exercise and Nutrition Program in Improving Physical Activity and Dietary Behavior in Non-Active, Overweight, or Obese Latinas

OHSU Knight Cancer Institute

NCT03028935

COMPLETED NA 12 participants

PACE-CALL: A Weight Control Intervention for Survivors of Childhood Leukemia

University of California, San Diego

NCT01171599

COMPLETED 10 participants

Implementation of a Cardiometabolic Disease Staging System in Primary Care

University of Alabama at Birmingham

NCT04922294

COMPLETED NA 9 participants

Absorption and Metabolic Profiles of a Sugar-based Beverage

Clinical Nutrition Research Center, Illinois Institute of Technology

NCT02226250

COMPLETED NA 8 participants

The Effects of Leucine on Body Weight

Columbia University

NCT00683826

COMPLETED NA 8 participants

Timing of Meals for Weight Loss

The University of Tennessee, Knoxville

NCT02204735

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Phase Distribution

PhaseTrial count
Phase 1 21
Phase 2 25
Phase 3 36
Phase 4 1

Named interventions

Most-linked intervention names on Overweight records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
43 trials
Tirzepatide Drug
15 trials
Orforglipron Drug
9 trials
Placebo Other
7 trials
Eloralintide Drug
5 trials
Retatrutide Drug
5 trials
Placebo Dietary supplement
4 trials
Maridebart Cafraglutide Drug
3 trials

US sites by state

Facility locations filed on Overweight trials. A trial with sites in several states counts in each.

California 74 trials
Florida 48 trials
Texas 33 trials
Arizona 32 trials
Georgia 27 trials
New York 25 trials
Illinois 21 trials
Alabama 21 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Overweight page

198 registered trials, 50 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Overweight condition card totals 198 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.