Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Overweight or Obesity
Open-data reference.
33 US clinical trials · 19 currently recruiting
Active & Recent Trials
Healthy Living BEYOND Weight Study
American Heart Association
NCT07075341
Taxi ROADmAP (Realizing Optimization Around Diet And Physical Activity)
Memorial Sloan Kettering Cancer Center
NCT05770570
Community Park-Based Programs for Health Promotion: The Fit2Lead Prospective Cohort Study
Duke University
NCT06596265
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
Eli Lilly and Company
NCT07353931
A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1
Eli Lilly and Company
NCT06948435
NDPP-NextGen: A Clinical Trial to Reduce Intergenerational Obesity and Diabetes Risks
Wake Forest University Health Sciences
NCT05674799
eMOTION: Examining Affective Mechanisms in Physical Activity Engagement
University of Southern California
NCT06570642
Promote Weight Loss in Obese Peripheral Artery Disease (PAD) Patients to Prevent Mobility Loss
Northwestern University
NCT04228978
A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)
Eli Lilly and Company
NCT06864026
Semaglutide for Metabolic Intervention and Adipose Loss to Treat Atrial Fibrillation
University of Chicago
NCT06499857
A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)
Eli Lilly and Company
NCT06857942
Better Lifestyle Counseling for African American Women During Pregnancy
University of Illinois at Chicago
NCT05234125
A Study of LY4064912 in Healthy Participants and With Overweight or Obesity
Eli Lilly and Company
NCT07152002
eMOTION: Examining Implicit Attitudes in Physical Activity Engagement
University of Southern California
NCT07044570
Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of BGM1812 Injection Following Single and Multiple Subcutaneous Administration in Normal to Overweight or Obese But Otherwise Healthy Men and Women
BrightGene Bio-Medical Technology Co.
NCT07224399
Craving Network Neurofeedback
Yale University
NCT06426693
Remotely Delivered Resistance Training for Cardiometabolic Health Among Black Women
University of Alabama at Birmingham
NCT06360536
Postprandial Effects of Animal Versus Plant-Based Protein
Ball State University
NCT06445296
The Acute T-Rex (Timing of Resistance Exercise) Study
University of Utah
NCT06366399
A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities
Eli Lilly and Company
NCT05869903
A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk
Eli Lilly and Company
NCT05803421
A Master Protocol for Orforglipron in Participants With Obstructive Sleep Apnea and Obesity or Overweight
Eli Lilly and Company
NCT06649045
Biological Sample Repository for Gastrointestinal Disorders
Pichamol Jirapinyo, MD, MPH
NCT05874726
A Phase 2b Study to Evaluate the Efficacy and Safety of Once-Monthly MET097 in Adults With Obesity or Overweight
Metsera, a wholly owned subsidiary of Pfizer
NCT06973720
A Phase 2b Study to Examine the Safety and Efficacy of Once-Weekly MET097 in Adults With Obesity or Overweight
Metsera, a wholly owned subsidiary of Pfizer
NCT06712836
Technology-Supported Treatment of Sleep Apnea in Prediabetes
University of Chicago
NCT04225507
Berries, Inflammation, and Gut Microbiome
Clinical Nutrition Research Center, Illinois Institute of Technology
NCT04100200
Pulses Consumption and Its Role in Managing Systemic Inflammation, Insulin Sensitivity and Gut Microbiome in Human
Clinical Nutrition Research Center, Illinois Institute of Technology
NCT04267705
Hepatic Energy Fluxes in NASH and NAS Patients
University of Minnesota
NCT03997422
Functional Fitness for Overweight or Obese Adults with Mobility Disabilities
University of Kansas
NCT05880966
Indigenous Supported Agriculture "Go Healthy"
Oklahoma State University Center for Health Sciences
NCT05773833
eMOTION Formative Study
University of Southern California
NCT06125964
Binge Eating Self-help for Teens ONLINE Pilot and Feasibility Study
Yale University
NCT06107387
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 2 |
| Phase 2 | 3 |
| Phase 3 | 6 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Overweight or Obesity Trial Landscape
ClinicalTrials.gov lists 33 US studies indexed under Overweight or Obesity, and 19 of those are currently open to recruitment — roughly 58% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Overweight or Obesity shows 8 late-stage studies (Phase 3 and Phase 4 combined) alongside 5 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Overweight or Obesity is led by Eli Lilly and Company with 8 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 33 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Overweight or Obesity?
PlainTrial tracks 33 US clinical trials for Overweight or Obesity, of which 19 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Overweight or Obesity?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.