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NCT05869903 · ClinicalTrials.gov registry record · Phase 3
A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities
A Phase 3 study of Obesity and Overweight, sponsored by Eli Lilly and Company.
- Active
- Registry status
- Phase 3
- Development phase
- 3,127
- Enrollment target
- 20
- Study locations
NCT05869903 is a Phase 3 study of Obesity and Overweight that is active but no longer recruiting, run by Eli Lilly and Company. The registered enrollment target is 3,127 participants, above the 816-participant average among 1,053 other Obesity trials with a reported enrollment target (283% higher). The trial reports 20 study locations across 6 states.
The verdict
NCT05869903, a Phase 3 study of Obesity and Overweight, is active but no longer recruiting, sponsored by Eli Lilly and Company.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 3,127 participants
- Enrollment target
- 20
- Study locations
Study Summary
This study will investigate the efficacy and safety of once daily oral orforglipron in adult participants with obesity or overweight with weight-related comorbidities. The study has two phases: a main phase and an extension phase. The main phase of the study lasted 72 weeks. Participants with prediabetes will continue in the extension for another 2 years.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Orforglipron
Study Locations (20)
California
- John Muir Physician Network Research Center - Concord
- AMCR Institute - Escondido
- NorCal Medical Research, Inc - Greenbrae
- Velocity Clinical Research, Huntington Park - Huntington Park
- Velocity Clinical Research, Westlake - Los Angeles
- Catalina Research Institute, LLC - Montclair
- Norcal Endocrinology & Internal Medicine - San Ramon
- University Clinical Investigators, Inc. - Tustin
Florida
- New Age Medical Research Corporation - Miami
- South Broward Research - Miramar
- Renstar Medical Research - Ocala
- Jedidiah Clinical Research - Tampa - Bay Plaza - Tampa
- Clinical Site Partners, LLC dba Flourish Research - Winter Park
Georgia
- Physicians Research Associates - Lawrenceville
- East Coast Institute for Research, LLC - Macon
- Rophe Adult and Pediatric Medicine/SKYCRNG - Union City
Arizona
- The Institute for Liver Health II dba Arizona Clinical Trials - Mesa - Chandler
- Clinical Research Institute of Arizona (CRI) - Sun City West - Sun City West
Colorado
- University of Colorado Anschutz Medical Campus - Aurora
Hawaii
- East-West Medical Research Institute - Honolulu
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3,127 participants |
| Start Date | 2023-06-05 |
| Est. Completion | 2027-10 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05869903
The ClinicalTrials.gov registry entry for NCT05869903 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 3,127 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 816-participant average among 1,053 other Obesity trials with a reported enrollment target (283% higher). The listed sponsor is Eli Lilly and Company, which has 1,341 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Obesity appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05869903 reports 20 study locations spanning 6 distinct geographic areas - top geographies include California, Florida, Georgia.
Frequently Asked Questions
What is clinical trial NCT05869903 about?
NCT05869903 is a clinical study titled "A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities". This study will investigate the efficacy and safety of once daily oral orforglipron in adult participants with obesity or overweight with weight-related comorbidities. The study has two phases: a main phase and an extension phase. The main phase of the study lasted 72 weeks. Participants with predia...
What is the current status of trial NCT05869903?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 3,127 participants. The study started on 2023-06-05. Estimated completion is 2027-10.
What conditions does trial NCT05869903 study?
This clinical trial studies the following conditions: Obesity, Overweight, Overweight or Obesity.
What interventions are being tested in trial NCT05869903?
The interventions under investigation include: Placebo (DRUG), Orforglipron (DRUG).
Who is sponsoring clinical trial NCT05869903?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05869903 being conducted?
This trial has 20 study locations across Arizona, California, Colorado, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.