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Overweight and Obesity: early-phase trial registry
40 of 116 indexed Overweight and Obesity trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #109 of 28,707 conditions by registered trial count.
116 US clinical trials · 40 currently recruiting · #109 of 28,707 conditions by registered trial count
Overweight and Obesity: 116 US clinical trials tracked, 40 recruiting.
Overweight and Obesity is the subject of 116 registered US clinical trials on ClinicalTrials.gov, 40 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is University of Colorado, Denver, running 8 of these trials.
Enrollment posture brief
Registry condition overweight-and-obesity
OPEN 40 | RECR 34% | LATE 2 | EARLY 12 | RANK #109 | SPON 8
Volume-matched condition peers
Nearest open-share peer: Colitis, Ulcerative (34% recruiting · 29 trials)
Overweight and Obesity lists 40 open slots (34% of 116 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Overweight and Obesity on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Overweight and Obesity is recruiting below its size-band peers.
40 of 116 indexed trials (34.5%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Overweight and Obesity trials is spread across many organizations.
University of Colorado, Denver accounts for 8 of 116 trials (6.9%). 79 distinct sponsors appear on at least one study for this condition label.
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Typical Overweight and Obesity enrolment sits around 100 participants.
Median target enrolment is 100 among the 116 trials that report a genuine target (sentinel values excluded). 58 of those (50%) plan for fewer than 100 participants.
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Overweight and Obesity research is mostly interventional.
109 interventional and 7 observational studies make up this index (94% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
116 total, page 2 of 3
Daily Caloric Restriction in ADPKD
University of Colorado, Denver
NCT04907799
An Open Label 100 Person Study Evaluating a Natural Supplement for Weight Loss and Fat Loss.
Prostasis, LLC, dba Tonum Health
NCT07152470
Fitbit Device Use in Overweight Pregnancy
University of Arizona
NCT06226597
Training Effects on Fuel Metabolism
University of Minnesota
NCT02150889
Targeting Weight and Shape Concern Among Women with High Body Weight
The Miriam Hospital
NCT05845866
Use of Empagliflozin to Treat Prediabetes
Oregon State University
NCT05426525
TREAT to Improve Cardiometabolic Health
Columbia University
NCT04465721
Fasting ENHANCE Pilot Study
University of Florida
NCT05732935
Telehealth Weight Loss Program for Breast Cancer Survivors
Abramson Cancer Center at Penn Medicine
NCT04855552
Developing a Weight Management Class as a Recruitment Tool for an Online Weight Loss Program to Rural Illinois Residents
University of Illinois at Urbana-Champaign
NCT06406985
Time and Nutrient-Dependent Effects of Aerobic Exercise on Metabolism in Adults (TANDEM Study)
University of Colorado, Denver
NCT06311487
Postprandial Inflammation and Nuts (PIN) in Older Adults
Rutgers, The State University of New Jersey
NCT06348771
Dietary Oils to Sustain Energy Study
Ohio State University
NCT04975763
Improving Metabolic & Mental Health in Female Healthcare Shift Workers
Auburn University
NCT06158204
Evaluating the Influence of Diet-induced Weight Loss on Fat (Adipose) Tissue's Insulin Sensitivity and Testosterone Synthesis in Women With Overweight or Obesity, Insulin Resistance, and Hyperandrogenemia
University of Missouri-Columbia
NCT06998238
SWITCH Implementation Effectiveness Trial
Iowa State University
NCT04045288
Evaluation of the BOKS Before-school Physical Activity Program
Massachusetts General Hospital
NCT03190135
NOURISH+: Nourishing Our Understanding of Role Modeling to Improve Support and Health
Virginia Commonwealth University
NCT01361243
Train Your Brain - Executive Function
USDA Grand Forks Human Nutrition Research Center
NCT05938894
Healthy Mothers-Healthy Children Nutrition
University of Miami
NCT03866902
Promoting Lifestyle Change Via Tailored mHealth Feedback to Improve Health
University of Pittsburgh
NCT03367936
Fit and Strong! Plus Comparative Effectiveness Trial
University of Illinois at Chicago
NCT03180008
Daily Self-Weighing for Obesity Management in Primary Care
University of Alabama at Birmingham
NCT04044794
Randomized Trial Of Achieving Healthy Lifestyles In Psych Rehabilitation
Johns Hopkins University
NCT00902694
Tailored Lifestyle Intervention in Obese Adults Within Primary Care Practice - Choose to Lose
Memorial Hospital of Rhode Island
NCT01542671
Healthy Summer Learners
University of South Carolina
NCT03321071
A Study of LY3305677 Compared With Placebo in Adult Participants With Obesity or Overweight
Eli Lilly and Company
NCT06124807
Madres Para la Salud (Mothers for Health)
Arizona State University
NCT01908959
Nonalcoholic Fatty Liver Disease and Atherosclerotic Risk in Children
Augusta University
NCT02383485
Strong People Strength Training Study
Cornell University
NCT04203563
Heart Health 4 New Moms: A Randomized Trial in the First Year After Preeclampsia
University of Pittsburgh
NCT03749746
Circadian Timing, Information Processing and Energy Balance Study
University of Utah
NCT04759755
Healthy Eating, Activity and Reduction of Teen Stress
Kent State University
NCT04038684
Behavioral Treatment for Weight Loss
Drexel University
NCT00746265
IgG-mediated Food Test for Weight Loss
University of Miami
NCT01592071
A Study to Evaluate the Safety and Efficacy of NG101 in Adult Participants Receiving a Glucagon-like Peptide-1 (GLP-1) Agonist
Neurogastrx
NCT06500429
Healthy Body Healthy Souls in the Marshallese Population
University of Arkansas
NCT03377244
UCSD Get Fit, Be Fit Study
University of California, San Diego
NCT03387709
PATH to Health: An Exploration of Digital Behavioral Weight Loss Approaches
University of North Carolina, Chapel Hill
NCT05929469
Pilot Study on the Effects of a Plant-Strong Diet on Cardiovascular Risk Factors
Phoenix VA Health Care System
NCT03330548
Dairy Foods and Weight Loss
USDA, Western Human Nutrition Research Center
NCT00858312
Safety and Efficacy of the SMART Device for Overweight and Obese Adults
Scientific Intake Limited
NCT02119299
Evaluation of a Lifestyle Medicine Practice
Ohio University
NCT03739034
A Trial to Assess Steviol Glycosides on Acute Appetite Hormone Release
Midwest Center for Metabolic and Cardiovascular Research
NCT05287906
ACT1ON Phase 2 (SMART Pilot) and Phase 3 (Efficacy Trial Development)
University of North Carolina, Chapel Hill
NCT03651622
Novel Executive Function Training for Obesity
University of California, San Diego
NCT03724396
Microalgae Extract Phaeosol Combined to Exercise in Healthy Overweight Women : Efficacy on Body Weight Management
Microphyt
NCT04761406
Optimizing Weight Loss Outcomes Through Body Image Enhancement
Texas Tech University
NCT05090293
Cognitive Behavioral Therapy for Adolescent Binge Eating and Loss of Control Eating
Yale University
NCT04088097
Improving Emotion Regulation Skills Among Adolescents Attempting to Lose Weight
Rhode Island Hospital
NCT03393221
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 8 |
| Phase 3 | 1 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Overweight and Obesity records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Overweight and Obesity trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Overweight and Obesity page
116 registered trials, 40 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 40 Overweight and Obesity trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Colorado, Denver sponsors the most Overweight and Obesity trials on record, review their full trial history before evaluating a specific study. See University of Colorado, Denver's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Overweight and Obesity condition card totals 116 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.