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NCT05732935 · ClinicalTrials.gov registry record · NA
Fasting ENHANCE Pilot Study
A NA study of Alzheimer Disease and Overweight and Obesity, sponsored by University of Florida.
- Active
- Registry status
- NA
- Development phase
- 52
- Enrollment target
- 1
- Study location
NCT05732935: Active NA study of Alzheimer Disease and Overweight and Obesity, sponsored by University of Florida.
NCT05732935 is a NA study of Alzheimer Disease and Overweight and Obesity that is active but no longer recruiting, run by University of Florida. The registered enrollment target is 52 participants, below the 2,751-participant average among 306 other Alzheimer Disease trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05732935, a NA study of Alzheimer Disease and Overweight and Obesity, is active but no longer recruiting, sponsored by University of Florida.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 52 participants
- Enrollment target
- 1
- Study location
Study Summary
Grounded in the principles of geroscience, the proposed Fasting ENHANCE study will test whether a time restricted eating (TRE) regimen can improve cognitive function and other aspects of successful aging in a safe and sustainable manner in at risk overweight older adults. Specifically, this study will evaluate whether TRE can improve cognitive and physical function, as well as self-reported sleep, mood, and quality of life, in overweight, older adults (age \> 65 years) who are at high risk of cognitive decline due to self-reported cognitive difficulties. Eligible participants will be assigned to either a TRE intervention, in which they will be instructed to fast for a target of 16 hours per day, or a successful aging (SA) comparison group for a 24-week period.
Primary Outcome
The RBANS is a neuropsychological battery of tests that has 4 repeatable forms that can be used longitudinally to measure cognitive change. It takes 30 minutes to administer and includes measures of five cognitive domains including immediate memory, visuospatial/constructional, language, attention, and delayed memory. This test is reliable in yielding results that recognize cognitive impairment associated with neurodegenerative disease. The RBANS can be used in predicting cognitive impairment wi
Conditions Studied
Interventions
- BEHAVIORAL Time Restricted Eating intervention
- BEHAVIORAL Successful Aging Comparison Group (LEARN)
Study Locations (1)
Florida
- Clinical and Translational Research Building - Institute on Aging Suite - Gainesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 52 participants |
| Start Date | 2023-03-13 |
| Est. Completion | 2026-06 |
| Phase | NA |
What the registry record for NCT05732935 still lists
NCT05732935 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 52 participants, a relatively small participant target, below the 2,751-participant average among 306 other Alzheimer Disease trials with a reported enrollment target (98% lower).
The record links to 3 conditions, with Alzheimer Disease appearing as the primary indexed condition, and to 2 interventions - of which Time Restricted Eating intervention is the first listed.
NCT05732935 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT05732935 about?
NCT05732935 is a clinical study titled "Fasting ENHANCE Pilot Study". Grounded in the principles of geroscience, the proposed Fasting ENHANCE study will test whether a time restricted eating (TRE) regimen can improve cognitive function and other aspects of successful aging in a safe and sustainable manner in at risk overweight older adults. Specifically, this study wi...
What is the current status of trial NCT05732935?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 52 participants. The study started on 2023-03-13. Estimated completion is 2026-06.
What conditions does trial NCT05732935 study?
This clinical trial studies the following conditions: Alzheimer Disease, Overweight and Obesity, Time Restricted Feeding.
What interventions are being tested in trial NCT05732935?
The interventions under investigation include: Time Restricted Eating intervention (BEHAVIORAL), Successful Aging Comparison Group (LEARN) (BEHAVIORAL).
Who is sponsoring clinical trial NCT05732935?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05732935 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05732935's enrollment target sits among peer trials
52 207th of 306 higher than 98 of 306 other Alzheimer Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alzheimer Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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