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Overweight and Obesity clinical trials
40 of 116 indexed Overweight and Obesity trials are currently recruiting.
116 US clinical trials · 40 currently recruiting
Overweight and Obesity is the subject of 116 registered US clinical trials on ClinicalTrials.gov, 40 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is University of Colorado, Denver, running 8 of these trials.
The research picture
Overweight and Obesity has 116 registered US clinical trials, 40 of them open to new participants right now, about 34% of the total.
- 40
- recruiting participants now
- 34%
- of trials open to enrollment
- 2
- in Phase 3–4 (later-stage)
- 8
- top sponsor: University of Colorado, Denver
Active & Recent Trials
116 total, page 3 of 3
Neural Response to Food Stimuli: fMRI Changes Following Cognitive Behavioral Therapy for Binge Eating Disorder
University of Pennsylvania
NCT03604172
Continuous Glucose Monitors (CGM) for Type 2 Diabetes (T2D) Risk Evaluation
Mary Ellen Vajravelu, MD
NCT05404711
Preventing Weight Gain Among Those Who Decline Behavioral Weight Loss Treatment (STEADY)
University of Florida
NCT04751656
Family Diabetes Prevention Program Pilot Study
Johns Hopkins University
NCT05358444
Effects of a 4-week Raw, Plant-based Diet on Anthropometric and Cardiovascular Risk Factors
Texas Woman's University
NCT03134235
Evaluation of Safety, Efficacy and Thermogenesis-induction of RZL-012 in Overweight and Obese Volunteers
Raziel Therapeutics
NCT03171415
Effect Cinnamon Spice on Postprandial Glucose and Insulin Responses
University of California, Los Angeles
NCT04686552
Mitochondrial Remodeling After Exercise
Oregon State University
NCT04103424
Relative Sarcopenia and Cardiometabolic Risk in Young Adults With Obesity
Massachusetts General Hospital
NCT04195061
A Technology-Based Intervention for the Reduction of Overweight and Obesity Among College Students
The University of Tennessee, Knoxville
NCT02196012
Inhibitory Control and Pediatric Weight Management
Cedars-Sinai Medical Center
NCT04747548
Improving Nutritional Choices in Adolescents
University of Michigan
NCT03693144
Influence of Adiposity on IGF-1 and Fitness Response to Exercise in Cancer Survivors
University of Colorado, Denver
NCT05558384
Oxytocin Effects on Food Motivation Pathways
Massachusetts General Hospital
NCT02276677
Daily Weight Feedback for Wheelchair Users to Promote Weight Loss
Jonathan Pearlman
NCT03264248
PlayFit Pilot: Encouraging Social Physical Play in the Community
Milton S. Hershey Medical Center
NCT02944370
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 8 |
| Phase 3 | 1 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Overweight and Obesity Trial Landscape
116 indexed Overweight and Obesity studies · 40 recruiting (34%).
Phase mix: 2 late (III/IV) vs 12 early (I/II).
Top sponsor: University of Colorado, Denver (8 trials), 9 others listed. 16 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Overweight and Obesity?
PlainTrial tracks 116 US clinical trials for Overweight and Obesity, of which 40 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Overweight and Obesity?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.