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ClinicalTrials.gov 40 recruiting now early-phase tilt #109 of 28,707 conditions

Overweight and Obesity: early-phase trial registry

40 of 116 indexed Overweight and Obesity trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #109 of 28,707 conditions by registered trial count.

116 US clinical trials · 40 currently recruiting · #109 of 28,707 conditions by registered trial count

Overweight and Obesity: 116 US clinical trials tracked, 40 recruiting.

Overweight and Obesity is the subject of 116 registered US clinical trials on ClinicalTrials.gov, 40 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is University of Colorado, Denver, running 8 of these trials.

Enrollment posture brief

Registry condition overweight-and-obesity

OPEN 40 | RECR 34% | LATE 2 | EARLY 12 | RANK #109 | SPON 8

Nearest open-share peer: Colitis, Ulcerative (34% recruiting · 29 trials)

Diffuse Large B Cell Lymphom46.1%Pain, Postoperative40.4%Metastatic Cancer40.2%Osteoarthritis, Knee39.1%Overweight and Obesity (this)34%
Open-enrollment share among volume-matched conditions near Overweight and Obesity

Overweight and Obesity lists 40 open slots (34% of 116 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Overweight and Obesity on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Overweight and Obesity is recruiting below its size-band peers.

    40 of 116 indexed trials (34.5%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Overweight and Obesity trials is spread across many organizations.

    University of Colorado, Denver accounts for 8 of 116 trials (6.9%). 79 distinct sponsors appear on at least one study for this condition label.

  3. Typical Overweight and Obesity enrolment sits around 100 participants.

    Median target enrolment is 100 among the 116 trials that report a genuine target (sentinel values excluded). 58 of those (50%) plan for fewer than 100 participants.

  4. Overweight and Obesity research is mostly interventional.

    109 interventional and 7 observational studies make up this index (94% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 28Phase 31Phase 41

Open and recent trials

116 total, page 3 of 3

COMPLETED NA 40 participants

Neural Response to Food Stimuli: fMRI Changes Following Cognitive Behavioral Therapy for Binge Eating Disorder

University of Pennsylvania

NCT03604172

COMPLETED NA 40 participants

Continuous Glucose Monitors (CGM) for Type 2 Diabetes (T2D) Risk Evaluation

Mary Ellen Vajravelu, MD

NCT05404711

COMPLETED NA 39 participants

Preventing Weight Gain Among Those Who Decline Behavioral Weight Loss Treatment (STEADY)

University of Florida

NCT04751656

COMPLETED NA 34 participants

Family Diabetes Prevention Program Pilot Study

Johns Hopkins University

NCT05358444

COMPLETED NA 33 participants

Effects of a 4-week Raw, Plant-based Diet on Anthropometric and Cardiovascular Risk Factors

Texas Woman's University

NCT03134235

COMPLETED Phase 2 32 participants

Evaluation of Safety, Efficacy and Thermogenesis-induction of RZL-012 in Overweight and Obese Volunteers

Raziel Therapeutics

NCT03171415

COMPLETED NA 32 participants

Effect Cinnamon Spice on Postprandial Glucose and Insulin Responses

University of California, Los Angeles

NCT04686552

COMPLETED NA 31 participants

Mitochondrial Remodeling After Exercise

Oregon State University

NCT04103424

COMPLETED 28 participants

Relative Sarcopenia and Cardiometabolic Risk in Young Adults With Obesity

Massachusetts General Hospital

NCT04195061

COMPLETED NA 23 participants

A Technology-Based Intervention for the Reduction of Overweight and Obesity Among College Students

The University of Tennessee, Knoxville

NCT02196012

COMPLETED NA 21 participants

Inhibitory Control and Pediatric Weight Management

Cedars-Sinai Medical Center

NCT04747548

COMPLETED NA 19 participants

Improving Nutritional Choices in Adolescents

University of Michigan

NCT03693144

COMPLETED NA 12 participants

Influence of Adiposity on IGF-1 and Fitness Response to Exercise in Cancer Survivors

University of Colorado, Denver

NCT05558384

COMPLETED Early Phase 1 10 participants

Oxytocin Effects on Food Motivation Pathways

Massachusetts General Hospital

NCT02276677

COMPLETED NA 9 participants

Daily Weight Feedback for Wheelchair Users to Promote Weight Loss

Jonathan Pearlman

NCT03264248

COMPLETED NA 8 participants

PlayFit Pilot: Encouraging Social Physical Play in the Community

Milton S. Hershey Medical Center

NCT02944370

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Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 8
Phase 3 1
Phase 4 1

Named interventions

Most-linked intervention names on Overweight and Obesity records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
5 trials
Control Behavioral
3 trials
Control Other
3 trials
CONTROL Other
3 trials
Counseling Behavioral
2 trials
Standard Behavioral Weight Control (SBWC) Behavioral
1 trials
Mindfulness-Based Weight Control (MBWC) Behavioral
1 trials
cinnamon Dietary supplement
1 trials

US sites by state

Facility locations filed on Overweight and Obesity trials. A trial with sites in several states counts in each.

California 16 trials
Pennsylvania 12 trials
Florida 10 trials
Colorado 8 trials
Texas 6 trials
Maryland 6 trials
Massachusetts 6 trials
Georgia 6 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Overweight and Obesity page

116 registered trials, 40 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Overweight and Obesity condition card totals 116 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.