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ClinicalTrials.gov 40 recruiting now official registry

Overweight and Obesity clinical trials

40 of 116 indexed Overweight and Obesity trials are currently recruiting.

116 US clinical trials · 40 currently recruiting

Overweight and Obesity is the subject of 116 registered US clinical trials on ClinicalTrials.gov, 40 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is University of Colorado, Denver, running 8 of these trials.

The research picture

Overweight and Obesity has 116 registered US clinical trials, 40 of them open to new participants right now, about 34% of the total.

40
recruiting participants now
34%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
8
top sponsor: University of Colorado, Denver
Phase 14Phase 28Phase 31Phase 41

Active & Recent Trials

116 total, page 3 of 3

COMPLETED NA 40 participants

Neural Response to Food Stimuli: fMRI Changes Following Cognitive Behavioral Therapy for Binge Eating Disorder

University of Pennsylvania

NCT03604172

COMPLETED NA 40 participants

Continuous Glucose Monitors (CGM) for Type 2 Diabetes (T2D) Risk Evaluation

Mary Ellen Vajravelu, MD

NCT05404711

COMPLETED NA 39 participants

Preventing Weight Gain Among Those Who Decline Behavioral Weight Loss Treatment (STEADY)

University of Florida

NCT04751656

COMPLETED NA 34 participants

Family Diabetes Prevention Program Pilot Study

Johns Hopkins University

NCT05358444

COMPLETED NA 33 participants

Effects of a 4-week Raw, Plant-based Diet on Anthropometric and Cardiovascular Risk Factors

Texas Woman's University

NCT03134235

COMPLETED Phase 2 32 participants

Evaluation of Safety, Efficacy and Thermogenesis-induction of RZL-012 in Overweight and Obese Volunteers

Raziel Therapeutics

NCT03171415

COMPLETED NA 32 participants

Effect Cinnamon Spice on Postprandial Glucose and Insulin Responses

University of California, Los Angeles

NCT04686552

COMPLETED NA 31 participants

Mitochondrial Remodeling After Exercise

Oregon State University

NCT04103424

COMPLETED 28 participants

Relative Sarcopenia and Cardiometabolic Risk in Young Adults With Obesity

Massachusetts General Hospital

NCT04195061

COMPLETED NA 23 participants

A Technology-Based Intervention for the Reduction of Overweight and Obesity Among College Students

The University of Tennessee, Knoxville

NCT02196012

COMPLETED NA 21 participants

Inhibitory Control and Pediatric Weight Management

Cedars-Sinai Medical Center

NCT04747548

COMPLETED NA 19 participants

Improving Nutritional Choices in Adolescents

University of Michigan

NCT03693144

COMPLETED NA 12 participants

Influence of Adiposity on IGF-1 and Fitness Response to Exercise in Cancer Survivors

University of Colorado, Denver

NCT05558384

COMPLETED Early Phase 1 10 participants

Oxytocin Effects on Food Motivation Pathways

Massachusetts General Hospital

NCT02276677

COMPLETED NA 9 participants

Daily Weight Feedback for Wheelchair Users to Promote Weight Loss

Jonathan Pearlman

NCT03264248

COMPLETED NA 8 participants

PlayFit Pilot: Encouraging Social Physical Play in the Community

Milton S. Hershey Medical Center

NCT02944370

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Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 8
Phase 3 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Overweight and Obesity Trial Landscape

116 indexed Overweight and Obesity studies · 40 recruiting (34%).

Phase mix: 2 late (III/IV) vs 12 early (I/II).

Top sponsor: University of Colorado, Denver (8 trials), 9 others listed. 16 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Overweight and Obesity?

PlainTrial tracks 116 US clinical trials for Overweight and Obesity, of which 40 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Overweight and Obesity?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.