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NCT07189871 · ClinicalTrials.gov registry record · Phase 1

177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

A Phase 1 study of Colorectal Cancer and Ovarian Cancer, sponsored by Radiopharm Theranostics.

Recruiting
Registry status
Phase 1
Development phase
61
Enrollment target
2
Study locations

NCT07189871 is a Phase 1 study of Colorectal Cancer and Ovarian Cancer that is actively recruiting participants, run by Radiopharm Theranostics. The registered enrollment target is 61 participants, below the 1,511-participant average among 369 other Colorectal Cancer trials with a reported enrollment target (96% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT07189871, a Phase 1 study of Colorectal Cancer and Ovarian Cancer, is actively recruiting participants, sponsored by Radiopharm Theranostics.

RECRUITING
Registry status
Phase 1
Development phase
61 participants
Enrollment target
2
Study locations

Study Summary

A Phase 1/2a Dose Escalation and Expansion Study of the Safety, Tolerability, and Preliminary Clinical Activity of 177LuBetaBart, a 177Lu-Labeled Anti-B7-H3 Monoclonal Antibody, in Patients with Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

Interventions

  • DRUG 177Lu-BetaBart

Study Locations (2)

Michigan

  • BAMF Health - Grand Rapids

Nebraska

  • Nebraska Cancer Specialists - Omaha

Trial Details

FieldValue
Enrollment Target 61 participants
Start Date 2026-02
Est. Completion 2027-12
Phase Phase 1

Sponsor

Radiopharm Theranostics

3 total trials

What the Registry Record Tells You About NCT07189871

The ClinicalTrials.gov registry entry for NCT07189871 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 61 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,511-participant average among 369 other Colorectal Cancer trials with a reported enrollment target (96% lower). The listed sponsor is Radiopharm Theranostics, which has 3 total studies on file at ClinicalTrials.gov.

The record links to 10 conditions, with Colorectal Cancer appearing as the primary indexed condition, and to 1 intervention - of which 177Lu-BetaBart is the first listed.

NCT07189871 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Michigan, Nebraska.

Frequently Asked Questions

What is clinical trial NCT07189871 about?

NCT07189871 is a clinical study titled "177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors". A Phase 1/2a Dose Escalation and Expansion Study of the Safety, Tolerability, and Preliminary Clinical Activity of 177LuBetaBart, a 177Lu-Labeled Anti-B7-H3 Monoclonal Antibody, in Patients with Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

What is the current status of trial NCT07189871?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 61 participants. The study started on 2026-02. Estimated completion is 2027-12.

What conditions does trial NCT07189871 study?

This clinical trial studies the following conditions: Colorectal Cancer, Ovarian Cancer, Endometrial Cancer, Cervical Cancer, TNBC - Triple-Negative Breast Cancer.

What interventions are being tested in trial NCT07189871?

The interventions under investigation include: 177Lu-BetaBart (DRUG).

Who is sponsoring clinical trial NCT07189871?

This trial is sponsored by Radiopharm Theranostics, which has 3 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07189871 being conducted?

This trial has 2 study locations across Michigan, Nebraska. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.