Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Obesity: early-phase trial registry
306 of 1,057 indexed Obesity trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #3 of 28,707 conditions by registered trial count.
1,057 US clinical trials · 306 currently recruiting · #3 of 28,707 conditions by registered trial count
Obesity: 1,057 US clinical trials tracked, 306 recruiting.
Obesity is the subject of 1,057 registered US clinical trials on ClinicalTrials.gov, 306 of them currently open to new participants. 107 are in Phase 3-4 (later-stage) and 196 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 48 of these trials.
Enrollment posture brief
Registry condition obesity
OPEN 306 | RECR 29% | LATE 107 | EARLY 196 | RANK #3 | SPON 48
Volume-matched condition peers
Nearest open-share peer: Metastatic Pancreatic Adenocarcinoma (29% recruiting · 38 trials)
Obesity lists 306 open slots (29% of 1,057 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Obesity on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Obesity is recruiting below its size-band peers.
306 of 1,057 indexed trials (28.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Obesity trials is spread across many organizations.
Eli Lilly and Company accounts for 48 of 1,057 trials (4.5%). 314 distinct sponsors appear on at least one study for this condition label.
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Typical Obesity enrolment sits around 90 participants.
Median target enrolment is 90 among the 1,054 trials that report a genuine target (sentinel values excluded). 555 of those (52.7%) plan for fewer than 100 participants.
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Obesity research is mostly interventional.
894 interventional and 163 observational studies make up this index (84.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
1,057 total, page 11 of 22
Evaluating the Relationship Between Physical Activity, Diet, Weight, and the Neighborhood Environment for Adolescents
Dr. James Sallis
NCT00608036
Improving High School Breakfast Environments
University of Minnesota
NCT02004977
Obesity Prevention in African American School Children
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00061165
Evaluation of a Walking School Bus Program
Seattle Children's Hospital
NCT01626807
Association of Genes to Resistance to Weight Loss in Obese Patients
Interleukin Genetics
NCT00858221
Promoting Successful Weight Loss in Primary Care in Louisiana
Pennington Biomedical Research Center
NCT02561221
Communicating Risk Information for Obesity
Boston University
NCT01355224
Study to Evaluate the Health and Wellness Policies of the New Haven Public School District.
Yale University
NCT02043626
Healthcare Utilization in Obese Caregiver Living Donors
University of Alabama at Birmingham
NCT04341896
Study of a Smart Growth Community's Effect on Prevention of Obesity in Middle-, Moderately Low- and Low-Income Families
University of Southern California
NCT00986011
Open-Label Extension (OLE) Study for Safety and Efficacy of Velneperit (S-2367) in Obese Subjects
Shionogi
NCT00788528
CV Disease in Adolescents With Type 2 Diabetes
Children's Hospital Medical Center, Cincinnati
NCT00114998
Pedestrian Behavior Following Implementation of a Walking School Bus
University of Washington
NCT00402701
Zonisamide SR Plus Bupropion SR Combination Therapy in Subjects With Obesity
Orexigen Therapeutics
NCT00709371
CARDIA Brain MRI Substudy
National Institute on Aging (NIA)
NCT01273311
Pragmatic Obstructive Sleep Apnea Weight Loss Trial Assessing Effectiveness and Reach
VA Office of Research and Development
NCT05104450
Metabolically Healthy Obesity: Correlations Between BMI and Metabolic Syndrome Biomarkers
St. Luke's-Roosevelt Hospital Center
NCT03195712
Health-Smart for Weight Loss at UF Jax Clinics
University of Florida
NCT03418701
HERO Study: Helping Evaluate Reduction in Obesity
Apollo Endosurgery
NCT00953173
Research Study to Investigate How Well Semaglutide Tablets Taken Once Daily Work in People Who Are Overweight or Living With Obesity (OASIS 1)
Novo Nordisk A/S
NCT05035095
Healthy Eating and Active Living Taught at Home (HEALTH) Dissemination & Implementation (D&I)
Washington University School of Medicine
NCT03758638
Social Incentives To Encourage Physical Activity and Understand Predictors
University of Pennsylvania
NCT03311230
Health Outcomes After Participating in Exercise (HOPE)
Wake Forest University Health Sciences
NCT03430115
A Study of Tirzepatide (LY3298176) In Participants After A Lifestyle Weight Loss Program
Eli Lilly and Company
NCT04657016
STAGES Trial: Study of Adiposity, Growth and Endocrine Stages
University of Utah
NCT01460784
Mothers in Motion Program to Prevent Weight Gain in WIC Mothers (MIM)
Ohio State University
NCT01839708
Coalition for a Healthier Community-Utah Women and Girls - Phase II (UWAG-II)
University of Utah
NCT02470156
Spatz3 Adjustable Balloon System® (Spatz3) Post Approval Study
Spatz FGIA
NCT05086302
Research Study to Investigate How Well Semaglutide Works in People Living With Heart Failure and Obesity
Novo Nordisk A/S
NCT04788511
A Research Study to See How Semaglutide Helps People With Excess Weight and Type 2 Diabetes Lose Weight
Novo Nordisk A/S
NCT05649137
A Safety and Efficacy Study Comparing Naltrexone SR/Bupropion SR and Placebo in Obese Subjects With Type 2 Diabetes
Orexigen Therapeutics
NCT00474630
A Research Study Comparing Wegovy to Other Weight Management Drugs in People Living With Obesity in America
Novo Nordisk A/S
NCT05579249
State-wide Health Approach to Increase Reach and Effectiveness: Study 1
The Miriam Hospital
NCT01264393
The Healthy Lifestyle Study
Robert Wood Johnson Foundation
NCT00119964
The GEM (Goals for Eating and Moving) Study
NYU Langone Health
NCT03006328
Methods for Measuring Insulin Sensitivity
National Center for Complementary and Integrative Health (NCCIH)
NCT00001625
Family Obesity Intervention: Motivational Interviewing and Community Support
Helena Laroche
NCT02425046
A Study to Evaluate the Change in Weight After 24 Weeks Treatment With LIK066 in Obese or Overweight Adults
Novartis Pharmaceuticals
NCT03100058
Healthy Eating and Active Living Taught at Home
Washington University School of Medicine
NCT01567033
Multi-level Communications and Access Strategies to Improve the Food Environment
Johns Hopkins Bloomberg School of Public Health
NCT02279849
Positive Action for Today's Health
University of South Carolina
NCT01025726
Family Nutrition Physical Activity Tool Use During Well Child Visits
University of Illinois at Chicago
NCT02067728
Weight Loss and Maintenance for Rural, African American Communities of Faith (The WORD)
University of Arkansas
NCT02169947
Anthropometric Assessment of Abdominal Obesity and Health Risk in Children and Adolescents
Pennington Biomedical Research Center
NCT01595100
Internet Assisted Obesity Treatment Enhanced With Financial Incentives
University of Vermont
NCT02688621
Healthy Home Offerings Via the Mealtime Environment (HOME) Plus
University of Minnesota
NCT01538615
Research Study Looking at How Well Semaglutide Works in People Suffering From Obesity and Knee Osteoarthritis
Novo Nordisk A/S
NCT05064735
Evaluation of Surgisis Gold Graft for Incision Reinforcement After Open Bariatric Surgery
Cook Group Incorporated
NCT00274625
The GoodNEWS Lifestyle Enhancement Program
University of Texas Southwestern Medical Center
NCT00669630
Nurturing Healthy Teachers
The University of Texas Health Science Center, Houston
NCT05542537
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 95 |
| Phase 2 | 101 |
| Phase 3 | 69 |
| Phase 4 | 38 |
Top Sponsors
Named interventions
Most-linked intervention names on Obesity records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Obesity trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Obesity page
1,057 registered trials, 306 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 306 Obesity trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Eli Lilly and Company sponsors the most Obesity trials on record, review their full trial history before evaluating a specific study. See Eli Lilly and Company's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Obesity condition card totals 1,057 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.