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Malignant Solid Neoplasm clinical trials
94 of 177 indexed Malignant Solid Neoplasm trials are currently recruiting.
177 US clinical trials · 94 currently recruiting
Malignant Solid Neoplasm is the subject of 177 registered US clinical trials on ClinicalTrials.gov, 94 of them currently open to new participants. 14 are in Phase 3-4 (later-stage) and 46 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 42 of these trials.
The research picture
Malignant Solid Neoplasm has 177 registered US clinical trials, 94 of them open to new participants right now, about 53% of the total.
- 94
- recruiting participants now
- 53%
- of trials open to enrollment
- 14
- in Phase 3–4 (later-stage)
- 42
- top sponsor: M.D. Anderson Cancer Center
Active & Recent Trials
177 total, page 4 of 4
Testing the Combination of Anti-Cancer Drugs Talazoparib and Temozolomide in Patients With Advanced Stage Rare Cancers, RARE 2 Trial
National Cancer Institute (NCI)
NCT05142241
Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)
National Cancer Institute (NCI)
NCT03213652
Ropidoxuridine and Whole Brain Radiation Therapy in Treating Patients With Brain Metastases
National Cancer Institute (NCI)
NCT02993146
Pegloticase for the Reduction of Uric Acid in Patients With Tumor Lysis Syndrome
M.D. Anderson Cancer Center
NCT04745910
On the BRINK: PhotoBiomodulation (PBM) for Mucositis in Patients Undergoing Allogeneic Hematopoietic Stem Cell TRansplant (HSCT) - Implementing the Evidence & Discovering New Knowledge
City of Hope Medical Center
NCT06625619
Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial
National Cancer Institute (NCI)
NCT04284774
Evaluation of Association Between Testosterone Levels, Dementia, and Adverse Mental Health Outcomes
M.D. Anderson Cancer Center
NCT04743466
Enhanced, EHR-facilitated Cancer Symptom Control Pragmatic Clinical Trial
Mayo Clinic
NCT03892967
Impact of Aminoglycosides in Hypotensive Septic Oncology Patients
M.D. Anderson Cancer Center
NCT05045963
Pro-Active Genetic Testing in Patients With Solid Tumors, Inherit Study
Mayo Clinic
NCT04456140
Perioperative Care in the Cancer Patient -1, ARCA-1 Study
M.D. Anderson Cancer Center
NCT04491409
Food Safety Educational Training Program to Improve Food Safety Knowledge and Behaviors in Cancer Patients Receiving Treatment
Ohio State University Comprehensive Cancer Center
NCT06630442
A Study of Physical Activity in Cancer Survivors
Mayo Clinic
NCT05988892
Evaluation of a Couple-Based Physical Activity Intervention
Mayo Clinic
NCT06073951
Geriatric Assessment Screening Tool for the Identification of At-Risk Older Adults Who Are Undergoing Cancer Treatment
Thomas Jefferson University
NCT04788758
Digital Meditation for Postoperative Pain Control After Abdominal Surgery for Cancer
Emory University
NCT05346692
The RIOT Trial: Re-Defining Frailty and Improving Outcomes With Prehabilitation for Pancreatic, Liver, or Gastric Cancer
Ohio State University Comprehensive Cancer Center
NCT04602026
Stress Echocardiography to Identify Chemotherapy Induced Cardiotoxicity in Cancer Patients With Heart Failure Risk
Mayo Clinic
NCT05950399
Development of the Oncology Opportunity Cost Assessment Tool
Thomas Jefferson University
NCT04694911
Whole Body Vibration for the Improvement of Health and Functioning in Participants With Chemotherapy-Induced Peripheral Neuropathy
OHSU Knight Cancer Institute
NCT04170075
Evaluation of Satisfaction With Quality of Care on the Palliative Care Unit
M.D. Anderson Cancer Center
NCT02686411
Pharmacist-led Transitions of Care in the Outpatient Oncology Infusion Center for Patients With Solid Tumor
Thomas Jefferson University
NCT04122118
Psychological, Psychophysical and Epigenetic Determinants of Chronic Pain After Cytoreductive - Hyperthermic Intraoperative Chemotherapy
M.D. Anderson Cancer Center
NCT05083338
Addressing Financial Hardship in Adolescent and Young Adult Cancer Survivors
Wake Forest University Health Sciences
NCT06881108
Ibrutinib for the Treatment of COVID-19 in Patients Requiring Hospitalization
Jennifer Woyach
NCT04439006
Clinical Outcomes for Offering Genetic Testing in a Tiered Approach
Fred Hutchinson Cancer Center
NCT04902144
Testing the Addition of an Anti-cancer Drug, Entinostat, to the Usual Chemotherapy and Immunotherapy Treatment (Atezolizumab, Carboplatin and Etoposide) for Previously Untreated Aggressive Lung Cancer That Has Spread
National Cancer Institute (NCI)
NCT04631029
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 24 |
| Phase 2 | 22 |
| Phase 3 | 12 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Malignant Solid Neoplasm Trial Landscape
177 indexed Malignant Solid Neoplasm studies · 94 recruiting (53%).
Phase mix: 14 late (III/IV) vs 46 early (I/II).
Top sponsor: M.D. Anderson Cancer Center (42 trials), 9 others listed. 27 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Malignant Solid Neoplasm?
PlainTrial tracks 177 US clinical trials for Malignant Solid Neoplasm, of which 94 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Malignant Solid Neoplasm?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.