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ClinicalTrials.gov 94 recruiting now early-phase tilt #62 of 28,707 conditions

Malignant Solid Neoplasm: early-phase trial registry

94 of 177 indexed Malignant Solid Neoplasm trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #62 of 28,707 conditions by registered trial count.

177 US clinical trials · 94 currently recruiting · #62 of 28,707 conditions by registered trial count

Malignant Solid Neoplasm: 177 US clinical trials tracked, 94 recruiting.

Malignant Solid Neoplasm is the subject of 177 registered US clinical trials on ClinicalTrials.gov, 94 of them currently open to new participants. 14 are in Phase 3-4 (later-stage) and 46 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 42 of these trials.

Enrollment posture brief

Registry condition malignant-solid-neoplasm

OPEN 94 | RECR 53% | LATE 14 | EARLY 46 | RANK #62 | SPON 42

Nearest open-share peer: Endometriosis (53% recruiting · 49 trials)

Alcohol Use Disorder58.9%Malignant Solid Neoplasm (th…53%Traumatic Brain Injury43.6%Bladder Cancer41.3%Cystic Fibrosis28.8%
Open-enrollment share among volume-matched conditions near Malignant Solid Neoplasm

Malignant Solid Neoplasm lists 94 open slots (53% of 177 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Malignant Solid Neoplasm on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Malignant Solid Neoplasm is recruiting above its size-band peers.

    94 of 177 indexed trials (53.1%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Malignant Solid Neoplasm research.

    M.D. Anderson Cancer Center accounts for 42 of 177 trials (23.7%). 29 distinct sponsors appear on at least one study for this condition label.

  3. Typical Malignant Solid Neoplasm enrolment sits around 105 participants.

    Median target enrolment is 105 among the 177 trials that report a genuine target (sentinel values excluded). 84 of those (47.5%) plan for fewer than 100 participants.

  4. Malignant Solid Neoplasm research is mostly interventional.

    128 interventional and 49 observational studies make up this index (72.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 124Phase 222Phase 312Phase 42

Open and recent trials

177 total, page 4 of 4

ACTIVE NOT RECRUITING Phase 2 14 participants

Testing the Combination of Anti-Cancer Drugs Talazoparib and Temozolomide in Patients With Advanced Stage Rare Cancers, RARE 2 Trial

National Cancer Institute (NCI)

NCT05142241

ACTIVE NOT RECRUITING Phase 2 13 participants

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

NCT03213652

ACTIVE NOT RECRUITING Phase 1 11 participants

Ropidoxuridine and Whole Brain Radiation Therapy in Treating Patients With Brain Metastases

National Cancer Institute (NCI)

NCT02993146

ACTIVE NOT RECRUITING Phase 4 10 participants

Pegloticase for the Reduction of Uric Acid in Patients With Tumor Lysis Syndrome

M.D. Anderson Cancer Center

NCT04745910

ACTIVE NOT RECRUITING 6 participants

On the BRINK: PhotoBiomodulation (PBM) for Mucositis in Patients Undergoing Allogeneic Hematopoietic Stem Cell TRansplant (HSCT) - Implementing the Evidence & Discovering New Knowledge

City of Hope Medical Center

NCT06625619

ACTIVE NOT RECRUITING Phase 2 5 participants

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

National Cancer Institute (NCI)

NCT04284774

ACTIVE NOT RECRUITING 1 participants

Evaluation of Association Between Testosterone Levels, Dementia, and Adverse Mental Health Outcomes

M.D. Anderson Cancer Center

NCT04743466

COMPLETED NA 50,207 participants

Enhanced, EHR-facilitated Cancer Symptom Control Pragmatic Clinical Trial

Mayo Clinic

NCT03892967

COMPLETED 232 participants

Impact of Aminoglycosides in Hypotensive Septic Oncology Patients

M.D. Anderson Cancer Center

NCT05045963

COMPLETED Phase 1 230 participants

Pro-Active Genetic Testing in Patients With Solid Tumors, Inherit Study

Mayo Clinic

NCT04456140

COMPLETED 229 participants

Perioperative Care in the Cancer Patient -1, ARCA-1 Study

M.D. Anderson Cancer Center

NCT04491409

COMPLETED NA 120 participants

Food Safety Educational Training Program to Improve Food Safety Knowledge and Behaviors in Cancer Patients Receiving Treatment

Ohio State University Comprehensive Cancer Center

NCT06630442

COMPLETED NA 100 participants

A Study of Physical Activity in Cancer Survivors

Mayo Clinic

NCT05988892

COMPLETED NA 96 participants

Evaluation of a Couple-Based Physical Activity Intervention

Mayo Clinic

NCT06073951

COMPLETED NA 76 participants

Geriatric Assessment Screening Tool for the Identification of At-Risk Older Adults Who Are Undergoing Cancer Treatment

Thomas Jefferson University

NCT04788758

COMPLETED Early Phase 1 73 participants

Digital Meditation for Postoperative Pain Control After Abdominal Surgery for Cancer

Emory University

NCT05346692

COMPLETED NA 66 participants

The RIOT Trial: Re-Defining Frailty and Improving Outcomes With Prehabilitation for Pancreatic, Liver, or Gastric Cancer

Ohio State University Comprehensive Cancer Center

NCT04602026

COMPLETED NA 52 participants

Stress Echocardiography to Identify Chemotherapy Induced Cardiotoxicity in Cancer Patients With Heart Failure Risk

Mayo Clinic

NCT05950399

COMPLETED 40 participants

Development of the Oncology Opportunity Cost Assessment Tool

Thomas Jefferson University

NCT04694911

COMPLETED NA 38 participants

Whole Body Vibration for the Improvement of Health and Functioning in Participants With Chemotherapy-Induced Peripheral Neuropathy

OHSU Knight Cancer Institute

NCT04170075

COMPLETED 35 participants

Evaluation of Satisfaction With Quality of Care on the Palliative Care Unit

M.D. Anderson Cancer Center

NCT02686411

COMPLETED NA 26 participants

Pharmacist-led Transitions of Care in the Outpatient Oncology Infusion Center for Patients With Solid Tumor

Thomas Jefferson University

NCT04122118

COMPLETED 24 participants

Psychological, Psychophysical and Epigenetic Determinants of Chronic Pain After Cytoreductive - Hyperthermic Intraoperative Chemotherapy

M.D. Anderson Cancer Center

NCT05083338

COMPLETED 16 participants

Addressing Financial Hardship in Adolescent and Young Adult Cancer Survivors

Wake Forest University Health Sciences

NCT06881108

COMPLETED Phase 1 10 participants

Ibrutinib for the Treatment of COVID-19 in Patients Requiring Hospitalization

Jennifer Woyach

NCT04439006

COMPLETED NA 6 participants

Clinical Outcomes for Offering Genetic Testing in a Tiered Approach

Fred Hutchinson Cancer Center

NCT04902144

COMPLETED Phase 1 3 participants

Testing the Addition of an Anti-cancer Drug, Entinostat, to the Usual Chemotherapy and Immunotherapy Treatment (Atezolizumab, Carboplatin and Etoposide) for Previously Untreated Aggressive Lung Cancer That Has Spread

National Cancer Institute (NCI)

NCT04631029

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Phase Distribution

PhaseTrial count
Phase 1 24
Phase 2 22
Phase 3 12
Phase 4 2

Named interventions

Most-linked intervention names on Malignant Solid Neoplasm records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Questionnaire Administration Other
46 trials
Biospecimen Collection Procedure
41 trials
Survey Administration Other
32 trials
Best Practice Other
27 trials
Quality-of-Life Assessment Other
24 trials
Electronic Health Record Review Other
21 trials
Interview Other
17 trials
Computed Tomography Procedure
15 trials

US sites by state

Facility locations filed on Malignant Solid Neoplasm trials. A trial with sites in several states counts in each.

California 49 trials
Texas 44 trials
Arizona 30 trials
Minnesota 27 trials
Florida 25 trials
Alabama 18 trials
Colorado 15 trials
Pennsylvania 14 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Malignant Solid Neoplasm page

177 registered trials, 94 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Malignant Solid Neoplasm condition card totals 177 registered trials; most-linked intervention Questionnaire Administration; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.