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ClinicalTrials.gov 94 recruiting now official registry

Malignant Solid Neoplasm clinical trials

94 of 177 indexed Malignant Solid Neoplasm trials are currently recruiting.

177 US clinical trials · 94 currently recruiting

Malignant Solid Neoplasm is the subject of 177 registered US clinical trials on ClinicalTrials.gov, 94 of them currently open to new participants. 14 are in Phase 3-4 (later-stage) and 46 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 42 of these trials.

The research picture

Malignant Solid Neoplasm has 177 registered US clinical trials, 94 of them open to new participants right now, about 53% of the total.

94
recruiting participants now
53%
of trials open to enrollment
14
in Phase 3–4 (later-stage)
42
top sponsor: M.D. Anderson Cancer Center
Phase 124Phase 222Phase 312Phase 42

Active & Recent Trials

177 total, page 4 of 4

ACTIVE NOT RECRUITING Phase 2 14 participants

Testing the Combination of Anti-Cancer Drugs Talazoparib and Temozolomide in Patients With Advanced Stage Rare Cancers, RARE 2 Trial

National Cancer Institute (NCI)

NCT05142241

ACTIVE NOT RECRUITING Phase 2 13 participants

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

NCT03213652

ACTIVE NOT RECRUITING Phase 1 11 participants

Ropidoxuridine and Whole Brain Radiation Therapy in Treating Patients With Brain Metastases

National Cancer Institute (NCI)

NCT02993146

ACTIVE NOT RECRUITING Phase 4 10 participants

Pegloticase for the Reduction of Uric Acid in Patients With Tumor Lysis Syndrome

M.D. Anderson Cancer Center

NCT04745910

ACTIVE NOT RECRUITING 6 participants

On the BRINK: PhotoBiomodulation (PBM) for Mucositis in Patients Undergoing Allogeneic Hematopoietic Stem Cell TRansplant (HSCT) - Implementing the Evidence & Discovering New Knowledge

City of Hope Medical Center

NCT06625619

ACTIVE NOT RECRUITING Phase 2 5 participants

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

National Cancer Institute (NCI)

NCT04284774

ACTIVE NOT RECRUITING 1 participants

Evaluation of Association Between Testosterone Levels, Dementia, and Adverse Mental Health Outcomes

M.D. Anderson Cancer Center

NCT04743466

COMPLETED NA 50,207 participants

Enhanced, EHR-facilitated Cancer Symptom Control Pragmatic Clinical Trial

Mayo Clinic

NCT03892967

COMPLETED 232 participants

Impact of Aminoglycosides in Hypotensive Septic Oncology Patients

M.D. Anderson Cancer Center

NCT05045963

COMPLETED Phase 1 230 participants

Pro-Active Genetic Testing in Patients With Solid Tumors, Inherit Study

Mayo Clinic

NCT04456140

COMPLETED 229 participants

Perioperative Care in the Cancer Patient -1, ARCA-1 Study

M.D. Anderson Cancer Center

NCT04491409

COMPLETED NA 120 participants

Food Safety Educational Training Program to Improve Food Safety Knowledge and Behaviors in Cancer Patients Receiving Treatment

Ohio State University Comprehensive Cancer Center

NCT06630442

COMPLETED NA 100 participants

A Study of Physical Activity in Cancer Survivors

Mayo Clinic

NCT05988892

COMPLETED NA 96 participants

Evaluation of a Couple-Based Physical Activity Intervention

Mayo Clinic

NCT06073951

COMPLETED NA 76 participants

Geriatric Assessment Screening Tool for the Identification of At-Risk Older Adults Who Are Undergoing Cancer Treatment

Thomas Jefferson University

NCT04788758

COMPLETED Early Phase 1 73 participants

Digital Meditation for Postoperative Pain Control After Abdominal Surgery for Cancer

Emory University

NCT05346692

COMPLETED NA 66 participants

The RIOT Trial: Re-Defining Frailty and Improving Outcomes With Prehabilitation for Pancreatic, Liver, or Gastric Cancer

Ohio State University Comprehensive Cancer Center

NCT04602026

COMPLETED NA 52 participants

Stress Echocardiography to Identify Chemotherapy Induced Cardiotoxicity in Cancer Patients With Heart Failure Risk

Mayo Clinic

NCT05950399

COMPLETED 40 participants

Development of the Oncology Opportunity Cost Assessment Tool

Thomas Jefferson University

NCT04694911

COMPLETED NA 38 participants

Whole Body Vibration for the Improvement of Health and Functioning in Participants With Chemotherapy-Induced Peripheral Neuropathy

OHSU Knight Cancer Institute

NCT04170075

COMPLETED 35 participants

Evaluation of Satisfaction With Quality of Care on the Palliative Care Unit

M.D. Anderson Cancer Center

NCT02686411

COMPLETED NA 26 participants

Pharmacist-led Transitions of Care in the Outpatient Oncology Infusion Center for Patients With Solid Tumor

Thomas Jefferson University

NCT04122118

COMPLETED 24 participants

Psychological, Psychophysical and Epigenetic Determinants of Chronic Pain After Cytoreductive - Hyperthermic Intraoperative Chemotherapy

M.D. Anderson Cancer Center

NCT05083338

COMPLETED 16 participants

Addressing Financial Hardship in Adolescent and Young Adult Cancer Survivors

Wake Forest University Health Sciences

NCT06881108

COMPLETED Phase 1 10 participants

Ibrutinib for the Treatment of COVID-19 in Patients Requiring Hospitalization

Jennifer Woyach

NCT04439006

COMPLETED NA 6 participants

Clinical Outcomes for Offering Genetic Testing in a Tiered Approach

Fred Hutchinson Cancer Center

NCT04902144

COMPLETED Phase 1 3 participants

Testing the Addition of an Anti-cancer Drug, Entinostat, to the Usual Chemotherapy and Immunotherapy Treatment (Atezolizumab, Carboplatin and Etoposide) for Previously Untreated Aggressive Lung Cancer That Has Spread

National Cancer Institute (NCI)

NCT04631029

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Phase Distribution

PhaseTrial count
Phase 1 24
Phase 2 22
Phase 3 12
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Malignant Solid Neoplasm Trial Landscape

177 indexed Malignant Solid Neoplasm studies · 94 recruiting (53%).

Phase mix: 14 late (III/IV) vs 46 early (I/II).

Top sponsor: M.D. Anderson Cancer Center (42 trials), 9 others listed. 27 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Malignant Solid Neoplasm?

PlainTrial tracks 177 US clinical trials for Malignant Solid Neoplasm, of which 94 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Malignant Solid Neoplasm?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.