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NCT00047385 · ClinicalTrials.gov registry record · Phase 3

National Lung Screening Trial (NLST) Screening

A Phase 3 study of Lung Cancer, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 3
Development phase
53,454
Enrollment target
20
Study locations

NCT00047385 is a Phase 3 study of Lung Cancer that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 53,454 participants, above the 805-participant average among 409 other Lung Cancer trials with a reported enrollment target (6540% higher). The trial reports 20 study locations across 15 states.

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The verdict

NCT00047385, a Phase 3 study of Lung Cancer, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 3
Development phase
53,454 participants
Enrollment target
20
Study locations

Study Summary

RATIONALE: Effective screening tests should help doctors detect lung cancer early and plan curative treatment. It is not yet known whether low-dose helical computed tomography (LDCT) screening is more effective than chest radiography (CXR) screening in reducing death from lung cancer. PURPOSE: Randomized clinical trial to compare the effectiveness of LDCT scan with that of CXR in screening individuals who are at high risk for developing lung cancer.

Conditions Studied

Interventions

  • DEVICE low-dose helical computed tomography
  • DEVICE chest radiography

Study Locations (20)

California

  • Univeristy of California, San Diego - La Jolla
  • Jonsson Comprehensive Cancer Center, UCLA - Los Angeles

Florida

  • Mayo Clinic - Jacksonville
  • H. Lee Moffitt Cancer Center and Research Institute - Tampa

Massachusetts

  • Brigham and Women's Hospital - Boston
  • Beth Israel Deaconess Medical Center - Boston

Michigan

  • University of Michigan Comprehensive Cancer Center - Ann Arbor
  • Henry Ford Health System - Detroit

Minnesota

  • University of Minnesota School of Public Health - Minneapolis
  • Mayo Clinic Cancer Center - Rochester

Alabama

  • University of Alabama at Birmingham - Birmingham

Colorado

  • University of Colorado Denver - Denver

District of Columbia

  • Georgetown University Medical Center - Washington D.C.

Trial Details

FieldValue
Enrollment Target 53,454 participants
Start Date 2002-08
Est. Completion 2010-10
Phase Phase 3

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT00047385

The ClinicalTrials.gov registry entry for NCT00047385 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 53,454 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 805-participant average among 409 other Lung Cancer trials with a reported enrollment target (6540% higher). The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Lung Cancer appearing as the primary indexed condition, and to 2 interventions - of which low-dose helical computed tomography is the first listed.

NCT00047385 reports 20 study locations spanning 15 distinct geographic areas - top geographies include California, Florida, Massachusetts.

Frequently Asked Questions

What is clinical trial NCT00047385 about?

NCT00047385 is a clinical study titled "National Lung Screening Trial (NLST) Screening". RATIONALE: Effective screening tests should help doctors detect lung cancer early and plan curative treatment. It is not yet known whether low-dose helical computed tomography (LDCT) screening is more effective than chest radiography (CXR) screening in reducing death from lung cancer. PURPOSE: Rand...

What is the current status of trial NCT00047385?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 53,454 participants. The study started on 2002-08. Estimated completion is 2010-10.

What conditions does trial NCT00047385 study?

This clinical trial studies the following conditions: Lung Cancer.

What interventions are being tested in trial NCT00047385?

The interventions under investigation include: low-dose helical computed tomography (DEVICE), chest radiography (DEVICE).

Who is sponsoring clinical trial NCT00047385?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00047385 being conducted?

This trial has 20 study locations across Alabama, California, Colorado, District of Columbia, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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