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COMPLETED Phase 3

S9900: Surgery With or Without Combination Chemotherapy in Treating Patients With Non-small Cell Lung Cancer

NCT00004011 · View on ClinicalTrials.gov ↗

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known if surgery plus combination chemotherapy is more effective than surgery alone for non-small cell lung cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of surgery with or without combination chemotherapy in treating patients who have non-small cell lung cancer.

Conditions Studied

Interventions

  • DRUG carboplatin
  • DRUG paclitaxel
  • PROCEDURE conventional surgery

Study Locations (20)

California

  • Providence Saint Joseph Medical Center - Burbank — Burbank
  • Mount Diablo Medical Center — Concord
  • California Cancer Center — Fresno
  • Saint Agnes Cancer Center — Fresno
  • Sutter Health Western Division Cancer Research Group — Greenbrae
  • Loma Linda University Cancer Institute at Loma Linda University Medical Center — Loma Linda
  • Veterans Affairs Medical Center - Long Beach — Long Beach
  • USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles
  • Jonsson Comprehensive Cancer Center, UCLA — Los Angeles
  • CCOP - Bay Area Tumor Institute — Oakland
  • Huntington Cancer Center at Huntington Hospital — Pasadena

Alabama

  • University of Alabama at Birmingham Comprehensive Cancer Center — Birmingham
  • Comprehensive Cancer Institute — Huntsville
  • Huntsville Hospital — Huntsville
  • MBCCOP - Gulf Coast — Mobile
  • Montgomery Cancer Center — Montgomery
  • DCH Cancer Treatment Center — Tuscaloosa
  • Radiation Oncology Associates of West Alabama — Tuscaloosa

Arizona

  • Foundation for Cancer Research and Education — Phoenix
  • CCOP - Mayo Clinic Scottsdale Oncology Program — Scottsdale

Trial Details

FieldValue
Enrollment Target 354 participants
Start Date 1999-10
Est. Completion 2012-11
Phase Phase 3

Sponsor

SWOG Cancer Research Network

212 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00004011

The ClinicalTrials.gov registry entry for NCT00004011 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 354 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is SWOG Cancer Research Network, which has 212 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Lung Cancer appearing as the primary indexed condition, and to 3 interventions — of which carboplatin is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00004011 reports 20 study locations spanning 3 distinct geographic areas — top geographies include California, Alabama, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00004011 about?

NCT00004011 is a clinical study titled "S9900: Surgery With or Without Combination Chemotherapy in Treating Patients With Non-small Cell Lung Cancer". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known if surgery plus combination chemotherapy is more effective than surgery alone for non-small cell lung ca...

What is the current status of trial NCT00004011?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 354 participants. The study started on 1999-10. Estimated completion is 2012-11.

What conditions does trial NCT00004011 study?

This clinical trial studies the following conditions: Lung Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00004011?

The interventions under investigation include: carboplatin (DRUG), paclitaxel (DRUG), conventional surgery (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00004011?

This trial is sponsored by SWOG Cancer Research Network, which has 212 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00004011 being conducted?

This trial has 20 study locations across Alabama, Arizona, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial