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ClinicalTrials.gov 9 recruiting now early-phase tilt

Liver Transplant: early-phase trial registry

9 of 20 indexed Liver Transplant trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #848 of 28,707 conditions by registered trial count.

20 US clinical trials · 9 currently recruiting · #848 of 28,707 conditions by registered trial count

Liver Transplant: 20 US clinical trials tracked, 9 recruiting.

Liver Transplant is the subject of 20 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is TransMedics, running 4 of these trials.

Enrollment posture brief

Registry condition liver-transplant

OPEN 9 | RECR 45% | LATE 1 | EARLY 7 | RANK #848 | SPON 4

Nearest open-share peer: Germ Cell Tumor (45% recruiting · 20 trials)

Advanced or Metastatic Solid55%ALS50%Liver Transplant (this)45%Abdominal Pain25%Acute Myocardial Infarction25%
Open-enrollment share among volume-matched conditions near Liver Transplant

Liver Transplant lists 9 open slots (45% of 20 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Liver Transplant on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Liver Transplant is recruiting above its size-band peers.

    9 of 20 indexed trials (45%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Liver Transplant research.

    TransMedics accounts for 4 of 20 trials (20%). 14 distinct sponsors appear on at least one study for this condition label.

  3. Typical Liver Transplant enrolment sits around 74 participants.

    Median target enrolment is 74 among the 20 trials that report a genuine target (sentinel values excluded). 11 of those (55%) plan for fewer than 100 participants.

  4. Liver Transplant splits between interventional and observational designs.

    13 interventional and 7 observational studies make up this index (65% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 25Phase 31

Open and recent trials

20 total, page 1 of 1

RECRUITING 100,000 participants

US National OCS Liver Perfusion (OLP) Registry

TransMedics

NCT05940857

RECRUITING 1,000 participants

Proteogenomic Monitoring and Assessment of Liver Transplant Recipients

Northwestern University

NCT01644903

RECRUITING Phase 2 416 participants

Cytomegalovirus (CMV) Vaccine in Orthotopic Liver Transplant Candidates

National Institute of Allergy and Infectious Diseases (NIAID)

NCT06075745

RECRUITING Phase 2 340 participants

Expanding Liver Transplant Immunosuppression Minimization Via Everolimus

National Institute of Allergy and Infectious Diseases (NIAID)

NCT06280950

RECRUITING NA 286 participants

Auriculo-Nerve Stimulation on Post-Operative Opioid Requirement

Jacques E. Chelly

NCT05506878

RECRUITING NA 200 participants

Normothermic Machine Perfusion of Steatotic Livers for Expansion of Donor Organ Pool

Massachusetts General Hospital

NCT06088758

RECRUITING 40 participants

Liver Transplant CGM

Icahn School of Medicine at Mount Sinai

NCT07216508

RECRUITING Phase 2 40 participants

Biliary Anastomosis in Living Donor Liver Transplant With Amniotic Tissue

Choon Hyuck David Kwon

NCT07102550

RECRUITING Phase 1 20 participants

EVR and EPO for Liver Transplant Tolerance

National Institute of Allergy and Infectious Diseases (NIAID)

NCT06832189

ACTIVE NOT RECRUITING 166 participants

OCS Liver Perfusion (OLP) Post-Approval Registry

TransMedics

NCT05074160

ACTIVE NOT RECRUITING Phase 1 9 participants

Liver Transplantation With Tregs at MGH

National Institute of Allergy and Infectious Diseases (NIAID)

NCT03577431

COMPLETED 401 participants

Pediatric Liver Database

Medical College of Wisconsin

NCT00677625

COMPLETED 397 participants

Quantra QStat in Trauma and Liver Transplant

HemoSonics

NCT04312958

COMPLETED 74 participants

OCS Liver PROTECT Continued Access Protocol (CAP) Continuation Post-Approval Study

TransMedics

NCT05096754

COMPLETED NA 74 participants

OCS Liver PROTECT Continued Access Protocol

TransMedics

NCT04186221

COMPLETED Phase 2 73 participants

The Use of Hepatitis C Positive Livers in Hepatitis C Negative Liver Transplant Recipients

Fernanda P Silveira, MD, MS

NCT03819322

COMPLETED Phase 2 62 participants

Optimizing Immunosuppression Drug Dosing Via Phenotypic Precision Medicine

University of Florida

NCT03527238

COMPLETED Phase 3 56 participants

Efficacy, Safety and Tolerability of Everolimus in Combination With Reduced Exposure Cyclosporine or Tacrolimus in Paediatric Liver Transplant Recipients.

Novartis Pharmaceuticals

NCT01598987

COMPLETED NA 42 participants

Text Messaging for Adherence in Adolescent Liver Transplant Recipients

Stanford University

NCT01696331

COMPLETED NA 12 participants

Increasing Activity in Liver Transplant Patients

Mayo Clinic

NCT02058498

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 5
Phase 3 1

Named interventions

Most-linked intervention names on Liver Transplant records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

OCS Liver Device
3 trials
Everolimus Drug
2 trials
Introduction of everolimus with reduced cyclosporine or tacrolimus dose, the earliest 1 month and the latest 6 months after liver transplantation. Drug
1 trials
OCS Liver System Device
1 trials
PPM-based Computation Assisted Drug Dosing Other
1 trials
Quantra System Diagnostic test
1 trials
mesna Drug
1 trials
arTreg-CSB Biological
1 trials

US sites by state

Facility locations filed on Liver Transplant trials. A trial with sites in several states counts in each.

California 11 trials
Texas 8 trials
Pennsylvania 6 trials
New York 6 trials
Massachusetts 6 trials
Florida 6 trials
Nebraska 5 trials
Michigan 5 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Liver Transplant page

20 registered trials, 9 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 9 Liver Transplant trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • TransMedics sponsors the most Liver Transplant trials on record, review their full trial history before evaluating a specific study. See TransMedics's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Liver Transplant condition card totals 20 registered trials; most-linked intervention OCS Liver; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.