Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Liver Transplant

Open-data reference.

20 US clinical trials · 9 currently recruiting

Active & Recent Trials

RECRUITING 100,000 participants

US National OCS Liver Perfusion (OLP) Registry

TransMedics

NCT05940857

RECRUITING 1,000 participants

Proteogenomic Monitoring and Assessment of Liver Transplant Recipients

Northwestern University

NCT01644903

RECRUITING Phase 2 416 participants

Cytomegalovirus (CMV) Vaccine in Orthotopic Liver Transplant Candidates

National Institute of Allergy and Infectious Diseases (NIAID)

NCT06075745

RECRUITING Phase 2 340 participants

Expanding Liver Transplant Immunosuppression Minimization Via Everolimus

National Institute of Allergy and Infectious Diseases (NIAID)

NCT06280950

RECRUITING NA 286 participants

Auriculo-Nerve Stimulation on Post-Operative Opioid Requirement

Jacques E. Chelly

NCT05506878

RECRUITING NA 200 participants

Normothermic Machine Perfusion of Steatotic Livers for Expansion of Donor Organ Pool

Massachusetts General Hospital

NCT06088758

RECRUITING 40 participants

Liver Transplant CGM

Icahn School of Medicine at Mount Sinai

NCT07216508

RECRUITING Phase 2 40 participants

Biliary Anastomosis in Living Donor Liver Transplant With Amniotic Tissue

Choon Hyuck David Kwon

NCT07102550

RECRUITING Phase 1 20 participants

EVR and EPO for Liver Transplant Tolerance

National Institute of Allergy and Infectious Diseases (NIAID)

NCT06832189

ACTIVE NOT RECRUITING 166 participants

OCS Liver Perfusion (OLP) Post-Approval Registry

TransMedics

NCT05074160

ACTIVE NOT RECRUITING Phase 1 9 participants

Liver Transplantation With Tregs at MGH

National Institute of Allergy and Infectious Diseases (NIAID)

NCT03577431

COMPLETED 401 participants

Pediatric Liver Database

Medical College of Wisconsin

NCT00677625

COMPLETED 397 participants

Quantra QStat in Trauma and Liver Transplant

HemoSonics

NCT04312958

COMPLETED 74 participants

OCS Liver PROTECT Continued Access Protocol (CAP) Continuation Post-Approval Study

TransMedics

NCT05096754

COMPLETED NA 74 participants

OCS Liver PROTECT Continued Access Protocol

TransMedics

NCT04186221

COMPLETED Phase 2 73 participants

The Use of Hepatitis C Positive Livers in Hepatitis C Negative Liver Transplant Recipients

Fernanda P Silveira, MD, MS

NCT03819322

COMPLETED Phase 2 62 participants

Optimizing Immunosuppression Drug Dosing Via Phenotypic Precision Medicine

University of Florida

NCT03527238

COMPLETED Phase 3 56 participants

Efficacy, Safety and Tolerability of Everolimus in Combination With Reduced Exposure Cyclosporine or Tacrolimus in Paediatric Liver Transplant Recipients.

Novartis Pharmaceuticals

NCT01598987

COMPLETED NA 42 participants

Text Messaging for Adherence in Adolescent Liver Transplant Recipients

Stanford University

NCT01696331

COMPLETED NA 12 participants

Increasing Activity in Liver Transplant Patients

Mayo Clinic

NCT02058498

Phase Distribution

PhaseTrial count
Early Phase 1 2
Phase 2 5
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Liver Transplant Trial Landscape

ClinicalTrials.gov lists 20 US studies indexed under Liver Transplant, and 9 of those are currently open to recruitment — roughly 45% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Liver Transplant shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 7 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Liver Transplant is led by TransMedics with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 20 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Liver Transplant?

PlainTrial tracks 20 US clinical trials for Liver Transplant, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Liver Transplant?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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