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NCT03577431 · ClinicalTrials.gov registry record · Phase 1

Liver Transplantation With Tregs at MGH

A Phase 1 study of Liver Transplant, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Active
Registry status
Phase 1
Development phase
9
Enrollment target
1
Study location

NCT03577431 is a Phase 1 study of Liver Transplant that is active but no longer recruiting, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 9 participants, below the 5,458-participant average among 19 other Liver Transplant trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03577431, a Phase 1 study of Liver Transplant, is active but no longer recruiting, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
9 participants
Enrollment target
1
Study location

Study Summary

This is a single-center, prospective, open-label, non-randomized clinical trial exploring cellular therapy to facilitate immunosuppression withdrawal in liver transplant recipients.

Conditions Studied

Liver Transplant

Interventions

  • DRUG cyclophosphamide
  • DRUG everolimus
  • PROCEDURE leukapheresis
  • BIOLOGICAL arTreg-CSB
  • DRUG mesna

Study Locations (1)

Massachusetts

  • Massachusetts General Hospital: Transplantation - Boston

Trial Details

FieldValue
Enrollment Target 9 participants
Start Date 2019-03-29
Est. Completion 2027-04-06
Phase Phase 1

Sponsor

National Institute of Allergy and Infectious Diseases (NIAID)

2,006 total trials

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What the Registry Record Tells You About NCT03577431

The ClinicalTrials.gov registry entry for NCT03577431 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 9 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 5,458-participant average among 19 other Liver Transplant trials with a reported enrollment target (100% lower). The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Liver Transplant appearing as the primary indexed condition, and to 5 interventions - of which cyclophosphamide is the first listed.

NCT03577431 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT03577431 about?

NCT03577431 is a clinical study titled "Liver Transplantation With Tregs at MGH". This is a single-center, prospective, open-label, non-randomized clinical trial exploring cellular therapy to facilitate immunosuppression withdrawal in liver transplant recipients.

What is the current status of trial NCT03577431?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 9 participants. The study started on 2019-03-29. Estimated completion is 2027-04-06.

What conditions does trial NCT03577431 study?

This clinical trial studies the following conditions: Liver Transplant.

What interventions are being tested in trial NCT03577431?

The interventions under investigation include: cyclophosphamide (DRUG), everolimus (DRUG), leukapheresis (PROCEDURE), arTreg-CSB (BIOLOGICAL), mesna (DRUG).

Who is sponsoring clinical trial NCT03577431?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03577431 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.