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NCT05940857 · ClinicalTrials.gov registry record
US National OCS Liver Perfusion (OLP) Registry
A clinical trial of Liver Transplant, sponsored by TransMedics.
- Recruiting
- Registry status
- 100,000
- Enrollment target
- 20
- Study locations
NCT05940857: Recruiting study of Liver Transplant, sponsored by TransMedics.
NCT05940857 is a study of Liver Transplant that is actively recruiting participants, run by TransMedics. The registered enrollment target is 100,000 participants, above the 195-participant average among 19 other Liver Transplant trials with a reported enrollment target (51182% higher). The trial reports 20 study locations across 15 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05940857, a study of Liver Transplant, is actively recruiting participants, sponsored by TransMedics.
- RECRUITING
- Registry status
- 100,000 participants
- Enrollment target
- 20
- Study locations
Study Summary
This Registry is a sponsor-initiated, multi-center, observational, post-approval registry with an independent academic oversight. TransMedics has contracted with United Network for Organ Sharing (UNOS) the Federal manager of the U.S. national transplant outcomes registry to obtain data that is routinely collected by the Organ Procurement and Transplantation Network (OPTN) on all transplanted organs in the U.S. for both the OCS liver transplanted patients as well as patients transplanted using other preservation modalities. Additional data will be collected by participating centers using OCS Liver perfusion.
Primary Outcome
Recipients' patient and graft survival rates will be the primary clinical outcomes measures for all OCS Liver transplanted recipients compared to recipients receiving liver transplants using non-OCS preservation methods (cold static storage or other perfusion devices or a combination of both). This data will be obtained directly from UNOS/OPTN database.
Conditions Studied
Interventions
- DEVICE OCS Liver
Study Locations (20)
California
- University of California San Diego - La Jolla
- University of California San Francisco - San Francisco
Massachusetts
- Beth Israel Deaconess Medical Center - Boston
- Lahey Clinic Medical Center - Burlington
Michigan
- University of Michigan Medical Center - Ann Arbor
- Henry Ford Hospital - Detroit
North Carolina
- Carolinas Medical Center/Atrium Health - Charlotte
- Duke Medical Center - Durham
Texas
- UT Southwestern Medical Center - Dallas
- Houston Methodist - Houston
Alabama
- University of Alabama - Birmingham
Arizona
- Mayo Clinic Hospital Arizona - Phoenix
Florida
- Mayo Clinic Hospital Florida - Jacksonville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100,000 participants |
| Start Date | 2021-10-14 |
| Est. Completion | 2031-10 |
What NCT05940857 shows while recruiting
NCT05940857 is an observational study that tracks outcomes without assigning an intervention. Its 100,000 participants enrollment target places it among the larger protocols in the corpus, above the 195-participant average among 19 other Liver Transplant trials with a reported enrollment target (51182% higher).
The record links to 1 condition, with Liver Transplant appearing as the primary indexed condition, and to 1 intervention - of which OCS Liver is the first listed.
NCT05940857 names 20 study sites across 15 states, led by California, Massachusetts, Michigan.
Frequently Asked Questions
What is clinical trial NCT05940857 about?
NCT05940857 is a clinical study titled "US National OCS Liver Perfusion (OLP) Registry". This Registry is a sponsor-initiated, multi-center, observational, post-approval registry with an independent academic oversight. TransMedics has contracted with United Network for Organ Sharing (UNOS) the Federal manager of the U.S. national transplant outcomes registry to obtain data that is rout...
What is the current status of trial NCT05940857?
This trial is currently recruiting. The enrollment target is 100,000 participants. The study started on 2021-10-14. Estimated completion is 2031-10.
What conditions does trial NCT05940857 study?
This clinical trial studies the following conditions: Liver Transplant.
What interventions are being tested in trial NCT05940857?
The interventions under investigation include: OCS Liver (DEVICE).
Who is sponsoring clinical trial NCT05940857?
This trial is sponsored by TransMedics, which has 23 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05940857 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Liver Transplant
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05940857's enrollment target sits among peer trials
100,000 1st of 19 higher than 19 of 19 other Liver Transplant trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Liver Transplant trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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