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NCT06088758 · ClinicalTrials.gov registry record · NA

Normothermic Machine Perfusion of Steatotic Livers for Expansion of Donor Organ Pool

A NA study of Liver Transplant, sponsored by Massachusetts General Hospital.

Recruiting
Registry status
NA
Development phase
200
Enrollment target
1
Study location

NCT06088758 is a NA study of Liver Transplant that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 200 participants, below the 5,448-participant average among 19 other Liver Transplant trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06088758, a NA study of Liver Transplant, is actively recruiting participants, sponsored by Massachusetts General Hospital.

RECRUITING
Registry status
NA
Development phase
200 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to assess the ability of Normothermic Machine Perfusion (NMP) to resuscitate moderately steatotic livers for transplantation in patients. This will be a single-site clinical trial placing donor livers with 30-60% macrosteatosis on NMP, and then transplanting those that meet commonly accepted viability criteria. The results of this study could lead to a trial extending NMP transplantation to severely steatotic livers, further expanding the donor organ pool.

Conditions Studied

Liver Transplant

Interventions

  • DEVICE Normothermic machine perfusion (NMP) of steatotic liver

Study Locations (1)

Massachusetts

  • Massachusetts General Brigham - Boston

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2024-02-28
Est. Completion 2027-07-31
Phase NA

Sponsor

Massachusetts General Hospital

2,032 total trials

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What the Registry Record Tells You About NCT06088758

The ClinicalTrials.gov registry entry for NCT06088758 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 5,448-participant average among 19 other Liver Transplant trials with a reported enrollment target (96% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Liver Transplant appearing as the primary indexed condition, and to 1 intervention - of which Normothermic machine perfusion (NMP) of steatotic liver is the first listed.

NCT06088758 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT06088758 about?

NCT06088758 is a clinical study titled "Normothermic Machine Perfusion of Steatotic Livers for Expansion of Donor Organ Pool". The goal of this clinical trial is to assess the ability of Normothermic Machine Perfusion (NMP) to resuscitate moderately steatotic livers for transplantation in patients. This will be a single-site clinical trial placing donor livers with 30-60% macrosteatosis on NMP, and then transplanting those ...

What is the current status of trial NCT06088758?

This trial is currently recruiting. It is a NA study. The enrollment target is 200 participants. The study started on 2024-02-28. Estimated completion is 2027-07-31.

What conditions does trial NCT06088758 study?

This clinical trial studies the following conditions: Liver Transplant.

What interventions are being tested in trial NCT06088758?

The interventions under investigation include: Normothermic machine perfusion (NMP) of steatotic liver (DEVICE).

Who is sponsoring clinical trial NCT06088758?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06088758 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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