TransMedics
Trial Pipeline
Enhancing Heart Allograft Function With the OCS Heart System Trial
NCT07145515
US National TOP Registry
NCT06513091
US National OCS Heart Perfusion (OHP) Registry
NCT05915299
US National OCS Liver Perfusion (OLP) Registry
NCT05940857
OCS Liver Perfusion (OLP) Post-Approval Registry
NCT05074160
OCS Heart Perfusion Post-Approval Registry
NCT05047068
OCS DCD Heart + CAP Continued Follow-Up
NCT05741723
OCS™ Lung TOP Registry For Donor Lungs for Transplantation
NCT03639025
OCS Liver PROTECT Continued Access Protocol (CAP) Continuation Post-Approval Study
NCT05096754
OCS Liver PROTECT Continued Access Protocol
NCT04186221
Donors After Circulatory Death Heart Trial
NCT03831048
INSPIRE Continuation Post-Approval Study
NCT03868904
Heart EXPAND Continued Access Protocol
NCT03835754
OCS Lung Expand Post-Approval Study - Expand Follow-Up Data Collection
NCT04194398
International EXPAND Heart Pivotal Trial
NCT02323321
Randomized Study of Organ Care System Cardiac for Preservation of Donated Hearts for Eventual Transplantation
NCT00855712
Therapeutic Areas
What the Pipeline for TransMedics Shows
According to the ClinicalTrials.gov registry, TransMedics is linked to 16 US clinical trials across every stage of research activity. Of those, 4 studies are currently recruiting — about 25% of the sponsor's indexed portfolio — and 8 are already marked complete, representing roughly 50% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for TransMedics reports 0 late-stage studies (Phase 3 and Phase 4 combined) and 0 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for TransMedics is Heart Transplant with 6 linked trials, and 7 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.