Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Insulin Sensitivity: early-phase trial registry
16 of 30 indexed Insulin Sensitivity trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #519 of 28,707 conditions by registered trial count.
30 US clinical trials · 16 currently recruiting · #519 of 28,707 conditions by registered trial count
Insulin Sensitivity: 30 US clinical trials tracked, 16 recruiting.
Insulin Sensitivity is the subject of 30 registered US clinical trials on ClinicalTrials.gov, 16 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Pennington Biomedical Research Center, running 4 of these trials.
Enrollment posture brief
Registry condition insulin-sensitivity
OPEN 16 | RECR 53% | LATE 0 | EARLY 4 | RANK #519 | SPON 4
Volume-matched condition peers
Nearest open-share peer: Advanced Lung Non-Small Cell Carcinoma (53% recruiting · 15 trials)
Insulin Sensitivity lists 16 open slots (53% of 30 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Insulin Sensitivity on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Insulin Sensitivity is recruiting above its size-band peers.
16 of 30 indexed trials (53.3%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Insulin Sensitivity trials is spread across many organizations.
Pennington Biomedical Research Center accounts for 4 of 30 trials (13.3%). 18 distinct sponsors appear on at least one study for this condition label.
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Most Insulin Sensitivity trials plan to enrol fewer than 100 people.
Median target enrolment is 50 among the 30 trials that report a genuine target (sentinel values excluded). 26 of those (86.7%) plan for fewer than 100 participants.
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Insulin Sensitivity research is mostly interventional.
25 interventional and 5 observational studies make up this index (83.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
30 total, page 1 of 1
The Sweet Kids Study (Stevia on Weight and Energy Effect Over Time)
Arkansas Children's Hospital Research Institute
NCT05992688
Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth
University of Colorado, Denver
NCT04596592
Mechanisms of Ultrasound Neuromodulation Effects in Diabetes
Yale University
NCT06042517
Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling
University of Colorado, Denver
NCT06129110
Effect of Sleep Extension on Ceramides in People with Overweight and Obesity
University of Utah
NCT06180837
Metabolic Adaptations to Weight Loss With and Without Exercise
University of Michigan
NCT05806801
MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes
Kalie Tommerdahl
NCT05065372
Obesity, Insulin Resistance, and PASC: Persistent SARS-CoV-2
Stanford University
NCT05833217
Impact of Circulating and Tissue-specific Lipids on Vascular Function and Insulin Sensitivity in Chronic Night Shift Workers
Colorado State University
NCT06550115
Countermeasures to Circadian Misalignment
Colorado State University
NCT04966351
Saccharin and Acesulfame Potassium Consumption and Glucose Homeostasis in Older Adults With Prediabetes
Virginia Polytechnic Institute and State University
NCT05441982
Non-Nutritive Sweetener Consumption and Glucose Homeostasis in Older Adults With Prediabetes
Virginia Polytechnic Institute and State University
NCT05337098
Circadian Intervention to Improve Cardiometabolic Health
University of Utah
NCT05943626
The Acute T-Rex (Timing of Resistance Exercise) Study
University of Utah
NCT06366399
Effect of Pulsatile Hormone Administration on Insulin Action
Pennington Biomedical Research Center
NCT06216665
Effect of Physiologic Insulin Administration on Insulin Sensitivity and Cognition
Pennington Biomedical Research Center
NCT07265323
Pulses Consumption and Its Role in Managing Systemic Inflammation, Insulin Sensitivity and Gut Microbiome in Human
Clinical Nutrition Research Center, Illinois Institute of Technology
NCT04267705
Impact of Sleep Extension in Adolescents
University of Colorado, Denver
NCT03500458
Understanding Dose Related Effects of Strawberry
Clinical Nutrition Research Center, Illinois Institute of Technology
NCT06173765
Metabolic Health Improvement Program: Effects of a Workplace Sugary Beverages Sales Ban and Motivational Counseling
University of California, San Francisco
NCT05972109
Mediterranean Style Diet and Low Glycemic Responses
Purdue University
NCT03410719
Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim2)
The University of Texas Health Science Center at San Antonio
NCT02127125
Bariatric Surgery and Weight Loss on Energy Metabolism and Insulin Sensitivity
Pennington Biomedical Research Center
NCT00936130
A Randomized, Crossover Study to Assess the Effects of Dietary Fiber-containing Bars on Glucose and Insulin Responses
Midwest Center for Metabolic and Cardiovascular Research
NCT03796286
Mitochondrial Function in Circulating Cells and Muscle Tissue
University of Arkansas
NCT02700698
Effects of Potato Resistant Starch Intake on Insulin Sensitivity, Related Metabolic Markers and Satiety
Midwest Center for Metabolic and Cardiovascular Research
NCT03689738
Effects of Regular Activity on Physiology Between Recreational Athletes of Different Body Fatness
Florida State University
NCT05154422
Development of a Novel Method to Measure Insulin Sensitivity in Humans: A Pilot Study
Pennington Biomedical Research Center
NCT04774081
Low Dose Fat-Induced Insulin Resistance
University of Pennsylvania
NCT03479671
Effect of Novel Glucagon Receptor Antagonist REMD-477 on Glucose and Adipocyte Metabolism in T2DM
The University of Texas Health Science Center at San Antonio
NCT05093517
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Insulin Sensitivity records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Insulin Sensitivity trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Insulin Sensitivity page
30 registered trials, 16 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 16 Insulin Sensitivity trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Pennington Biomedical Research Center sponsors the most Insulin Sensitivity trials on record, review their full trial history before evaluating a specific study. See Pennington Biomedical Research Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Insulin Sensitivity condition card totals 30 registered trials; most-linked intervention Non-Nutritive Sweetener Intake and impact on glucose homeostasis; top US site state Colorado. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.