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Insulin Sensitivity clinical trials
Every US clinical trial registered for Insulin Sensitivity — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
30 US clinical trials · 16 currently recruiting
The research picture
Insulin Sensitivity has 30 registered US clinical trials, 16 of them open to new participants right now — about 53% of the total.
- 16
- recruiting participants now
- 53%
- of trials open to enrollment
- 0
- in Phase 3–4 (later-stage)
- 4
- top sponsor: Pennington Biomedical Research Center
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
The Sweet Kids Study (Stevia on Weight and Energy Effect Over Time)
Arkansas Children's Hospital Research Institute
NCT05992688
Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth
University of Colorado, Denver
NCT04596592
Mechanisms of Ultrasound Neuromodulation Effects in Diabetes
Yale University
NCT06042517
Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling
University of Colorado, Denver
NCT06129110
Effect of Sleep Extension on Ceramides in People with Overweight and Obesity
University of Utah
NCT06180837
Metabolic Adaptations to Weight Loss With and Without Exercise
University of Michigan
NCT05806801
MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes
Kalie Tommerdahl
NCT05065372
Obesity, Insulin Resistance, and PASC: Persistent SARS-CoV-2
Stanford University
NCT05833217
Impact of Circulating and Tissue-specific Lipids on Vascular Function and Insulin Sensitivity in Chronic Night Shift Workers
Colorado State University
NCT06550115
Countermeasures to Circadian Misalignment
Colorado State University
NCT04966351
Saccharin and Acesulfame Potassium Consumption and Glucose Homeostasis in Older Adults With Prediabetes
Virginia Polytechnic Institute and State University
NCT05441982
Non-Nutritive Sweetener Consumption and Glucose Homeostasis in Older Adults With Prediabetes
Virginia Polytechnic Institute and State University
NCT05337098
Circadian Intervention to Improve Cardiometabolic Health
University of Utah
NCT05943626
The Acute T-Rex (Timing of Resistance Exercise) Study
University of Utah
NCT06366399
Effect of Pulsatile Hormone Administration on Insulin Action
Pennington Biomedical Research Center
NCT06216665
Effect of Physiologic Insulin Administration on Insulin Sensitivity and Cognition
Pennington Biomedical Research Center
NCT07265323
Pulses Consumption and Its Role in Managing Systemic Inflammation, Insulin Sensitivity and Gut Microbiome in Human
Clinical Nutrition Research Center, Illinois Institute of Technology
NCT04267705
Impact of Sleep Extension in Adolescents
University of Colorado, Denver
NCT03500458
Understanding Dose Related Effects of Strawberry
Clinical Nutrition Research Center, Illinois Institute of Technology
NCT06173765
Metabolic Health Improvement Program: Effects of a Workplace Sugary Beverages Sales Ban and Motivational Counseling
University of California, San Francis
NCT05972109
Mediterranean Style Diet and Low Glycemic Responses
Purdue University
NCT03410719
Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim2)
The University of Texas Health Science Center at San Antonio
NCT02127125
Bariatric Surgery and Weight Loss on Energy Metabolism and Insulin Sensitivity
Pennington Biomedical Research Center
NCT00936130
A Randomized, Crossover Study to Assess the Effects of Dietary Fiber-containing Bars on Glucose and Insulin Responses
Midwest Center for Metabolic and Cardiovascular Research
NCT03796286
Mitochondrial Function in Circulating Cells and Muscle Tissue
University of Arkansas
NCT02700698
Effects of Potato Resistant Starch Intake on Insulin Sensitivity, Related Metabolic Markers and Satiety
Midwest Center for Metabolic and Cardiovascular Research
NCT03689738
Effects of Regular Activity on Physiology Between Recreational Athletes of Different Body Fatness
Florida State University
NCT05154422
Development of a Novel Method to Measure Insulin Sensitivity in Humans: A Pilot Study
Pennington Biomedical Research Center
NCT04774081
Low Dose Fat-Induced Insulin Resistance
University of Pennsylvania
NCT03479671
Effect of Novel Glucagon Receptor Antagonist REMD-477 on Glucose and Adipocyte Metabolism in T2DM
The University of Texas Health Science Center at San Antonio
NCT05093517
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Insulin Sensitivity Trial Landscape
ClinicalTrials.gov lists 30 US studies indexed under Insulin Sensitivity, and 16 of those are currently open to recruitment — roughly 53% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Insulin Sensitivity shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Insulin Sensitivity is led by Pennington Biomedical Research Center with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 30 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Insulin Sensitivity?
PlainTrial tracks 30 US clinical trials for Insulin Sensitivity, of which 16 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Insulin Sensitivity?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.