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NCT06550115 · ClinicalTrials.gov registry record · NA
Impact of Circulating and Tissue-specific Lipids on Vascular Function and Insulin Sensitivity in Chronic Night Shift Workers
A NA study of Blood Pressure and Metabolic Disease, sponsored by Colorado State University.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT06550115: Recruiting NA study of Blood Pressure and Metabolic Disease, sponsored by Colorado State University.
NCT06550115 is a NA study of Blood Pressure and Metabolic Disease that is actively recruiting participants, run by Colorado State University. The registered enrollment target is 50 participants, below the 286-participant average among 101 other Blood Pressure trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06550115, a NA study of Blood Pressure and Metabolic Disease, is actively recruiting participants, sponsored by Colorado State University.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
People who experience repeated bouts of circadian misalignment, such as shift workers, are at higher risk of cardiovascular disease (CVD) and Type 2 diabetes (T2D) compared to daytime workers. However, the mechanism(s) by which shift work and associated circadian misalignment increase CVD and T2D risk are unknown. This project will examine whether elevated plasma lipids are a mechanism by which circadian misalignment impairs vascular function, insulin sensitivity, glucose homeostasis and muscle lipid accumulation, which could be targeted to prevent and treat cardiometabolic disease in people who chronically experience circadian misalignment, which includes more than 20% of the US workforce.
Primary Outcome
Four weeks of TRE during shift work will reduce 24-hour blood pressure versus Control.
Conditions Studied
Interventions
- BEHAVIORAL Time-restricted eating
- BEHAVIORAL Control eating
Study Locations (1)
Colorado
- Colorado State University - Fort Collins
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2024-03-01 |
| Est. Completion | 2029-06 |
| Phase | NA |
What NCT06550115 shows while recruiting
NCT06550115 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 286-participant average among 101 other Blood Pressure trials with a reported enrollment target (83% lower).
The record links to 4 conditions, with Blood Pressure appearing as the primary indexed condition, and to 2 interventions - of which Time-restricted eating is the first listed.
NCT06550115 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT06550115 about?
NCT06550115 is a clinical study titled "Impact of Circulating and Tissue-specific Lipids on Vascular Function and Insulin Sensitivity in Chronic Night Shift Workers". People who experience repeated bouts of circadian misalignment, such as shift workers, are at higher risk of cardiovascular disease (CVD) and Type 2 diabetes (T2D) compared to daytime workers. However, the mechanism(s) by which shift work and associated circadian misalignment increase CVD and T2D ri...
What is the current status of trial NCT06550115?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2024-03-01. Estimated completion is 2029-06.
What conditions does trial NCT06550115 study?
This clinical trial studies the following conditions: Blood Pressure, Metabolic Disease, Insulin Sensitivity, Circadian Rhythm Sleep Disorder of Shift Work Type.
What interventions are being tested in trial NCT06550115?
The interventions under investigation include: Time-restricted eating (BEHAVIORAL), Control eating (BEHAVIORAL).
Who is sponsoring clinical trial NCT06550115?
This trial is sponsored by Colorado State University, which has 94 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06550115 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06550115's enrollment target sits among peer trials
50 57th of 101 higher than 41 of 101 other Blood Pressure trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Blood Pressure trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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