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NCT06129110 · ClinicalTrials.gov registry record · NA

Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling

A NA study of Obesity and Insulin Resistance, sponsored by University of Colorado, Denver.

Recruiting
Registry status
NA
Development phase
70
Enrollment target
1
Study location

NCT06129110 is a NA study of Obesity and Insulin Resistance that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 70 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06129110, a NA study of Obesity and Insulin Resistance, is actively recruiting participants, sponsored by University of Colorado, Denver.

RECRUITING
Registry status
NA
Development phase
70 participants
Enrollment target
1
Study location

Study Summary

The goal of this intervention study is to learn about how weight loss impacts molecular signaling of intermuscular adipose tissue (IMAT) in individuals with obesity. The main question it aims to answer is how inflammatory molecules secreted by IMAT promote muscle insulin resistance and inflammation, and how these same molecules are diminished after weight loss. Following screening visits involving body composition measures, blood testing, strength testing, and a thigh muscle biopsy, participants will go through a 12-week dietary intervention for weight loss. After 12 weeks, this will be followed by the same testing and biopsies that were completed before the intervention. Researchers will then compare outcomes of individuals who lost weight to individuals who did not lose weight.

Interventions

  • BEHAVIORAL Diet Weight Loss

Study Locations (1)

Colorado

  • University of Colorado Anschutz - Aurora

Trial Details

FieldValue
Enrollment Target 70 participants
Start Date 2024-01-01
Est. Completion 2029-12-01
Phase NA

Sponsor

University of Colorado, Denver

1,283 total trials

What the Registry Record Tells You About NCT06129110

The ClinicalTrials.gov registry entry for NCT06129110 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 70 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (91% lower). The listed sponsor is University of Colorado, Denver, which has 1,283 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Obesity appearing as the primary indexed condition, and to 1 intervention - of which Diet Weight Loss is the first listed.

NCT06129110 reports 1 study location spanning 1 distinct geographic area - top geographies include Colorado.

Frequently Asked Questions

What is clinical trial NCT06129110 about?

NCT06129110 is a clinical study titled "Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling". The goal of this intervention study is to learn about how weight loss impacts molecular signaling of intermuscular adipose tissue (IMAT) in individuals with obesity. The main question it aims to answer is how inflammatory molecules secreted by IMAT promote muscle insulin resistance and inflammation,...

What is the current status of trial NCT06129110?

This trial is currently recruiting. It is a NA study. The enrollment target is 70 participants. The study started on 2024-01-01. Estimated completion is 2029-12-01.

What conditions does trial NCT06129110 study?

This clinical trial studies the following conditions: Obesity, Insulin Resistance, Insulin Sensitivity, Muscle Weakness, Adiposity.

What interventions are being tested in trial NCT06129110?

The interventions under investigation include: Diet Weight Loss (BEHAVIORAL).

Who is sponsoring clinical trial NCT06129110?

This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06129110 being conducted?

This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.