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NCT07265323 · ClinicalTrials.gov registry record · NA
Effect of Physiologic Insulin Administration on Insulin Sensitivity and Cognition
A NA study of Alzheimers Disease and Insulin Sensitivity, sponsored by Pennington Biomedical Research Center.
- Recruiting
- Registry status
- NA
- Development phase
- 8
- Enrollment target
- 1
- Study location
NCT07265323: Recruiting NA study of Alzheimers Disease and Insulin Sensitivity, sponsored by Pennington Biomedical Research Center.
NCT07265323 is a NA study of Alzheimers Disease and Insulin Sensitivity that is actively recruiting participants, run by Pennington Biomedical Research Center. The registered enrollment target is 8 participants, below the 3,926-participant average among 147 other Alzheimers Disease trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07265323, a NA study of Alzheimers Disease and Insulin Sensitivity, is actively recruiting participants, sponsored by Pennington Biomedical Research Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 8 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to determine if a weekly delivery of insulin at short intervals lasting up to 2 hours can improve insulin sensitivity and cognition in adults with Alzheimer's Disease. It will also provide information about the safety and feasibility of this intervention. The main questions it aims to answer are: Does the intervention improve insulin sensitivity (how the body uses glucose)? Does the intervention improve cognition, measured by the Montreal Cognitive Assessment (MoCA) and the Revised Memory and Behavior Problems Checklist (RMBPC)? What changes occur in brain glucose uptake (FDG-PET)? Participants will: Receive the intervention once a week for 6 months, with each session lasting up to 2 hours Complete cognitive assessments. Adverse events will be assessed throughout the study.
Primary Outcome
Cognition will be assessed using Montreal Cognitive Assessment (MoCA). The MoCA test scores range from 0 to 30, with a higher score indicating a better outcome.
Conditions Studied
Interventions
- OTHER Physiological Insulin Intervention
Study Locations (1)
Louisiana
- Pennington Biomedical Research Center - Baton Rouge
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2025-12 |
| Est. Completion | 2027-05 |
| Phase | NA |
What NCT07265323 shows while recruiting
NCT07265323 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 3,926-participant average among 147 other Alzheimers Disease trials with a reported enrollment target (100% lower).
The record links to 3 conditions, with Alzheimers Disease appearing as the primary indexed condition, and to 1 intervention - of which Physiological Insulin Intervention is the first listed.
NCT07265323 reports a single indexed study location in Louisiana.
Frequently Asked Questions
What is clinical trial NCT07265323 about?
NCT07265323 is a clinical study titled "Effect of Physiologic Insulin Administration on Insulin Sensitivity and Cognition". The goal of this clinical trial is to determine if a weekly delivery of insulin at short intervals lasting up to 2 hours can improve insulin sensitivity and cognition in adults with Alzheimer's Disease. It will also provide information about the safety and feasibility of this intervention. The main...
What is the current status of trial NCT07265323?
This trial is currently recruiting. It is a NA study. The enrollment target is 8 participants. The study started on 2025-12. Estimated completion is 2027-05.
What conditions does trial NCT07265323 study?
This clinical trial studies the following conditions: Alzheimers Disease, Insulin Sensitivity, Alzheimer Blood Biomarkers.
What interventions are being tested in trial NCT07265323?
The interventions under investigation include: Physiological Insulin Intervention (OTHER).
Who is sponsoring clinical trial NCT07265323?
This trial is sponsored by Pennington Biomedical Research Center, which has 258 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07265323 being conducted?
This trial has 1 study location across Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Alzheimers Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07265323's enrollment target sits among peer trials
8 145th of 147 higher than 3 of 147 other Alzheimers Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alzheimers Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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