Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05337098 · ClinicalTrials.gov registry record · NA
Non-Nutritive Sweetener Consumption and Glucose Homeostasis in Older Adults With Prediabetes
A NA study of Insulin Sensitivity and Inflammatory Markers, sponsored by Virginia Polytechnic Institute and State University.
- Recruiting
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT05337098 is a NA study of Insulin Sensitivity and Inflammatory Markers that is actively recruiting participants, run by Virginia Polytechnic Institute and State University. The registered enrollment target is 30 participants, below the 72-participant average among 29 other Insulin Sensitivity trials with a reported enrollment target (58% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05337098, a NA study of Insulin Sensitivity and Inflammatory Markers, is actively recruiting participants, sponsored by Virginia Polytechnic Institute and State University.
- RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
Animal and observational research in humans suggest that specific types of non-nutritive sweeteners (NNS) may impair glycemic control. However, whether NNS consumption impacts glucose homeostasis in middle-aged/older adults with prediabetes is unknown, and potential mechanisms by which this could occur have yet to be identified. The overall objective of this R21 proposal is to establish proof-of-concept for alterations in glucose homeostasis following intake of sucralose, but not aspartame, in middle-aged/older adults with prediabetes compared to a eucaloric diet with no NNS.
Conditions Studied
Interventions
- OTHER Non-Nutritive Sweetener Intake and impact on glucose homeostasis
Study Locations (1)
Virginia
- Virginia Tech - Blacksburg
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2023-04-18 |
| Est. Completion | 2026-02-28 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05337098
The ClinicalTrials.gov registry entry for NCT05337098 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 72-participant average among 29 other Insulin Sensitivity trials with a reported enrollment target (58% lower). The listed sponsor is Virginia Polytechnic Institute and State University, which has 104 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Insulin Sensitivity appearing as the primary indexed condition, and to 1 intervention - of which Non-Nutritive Sweetener Intake and impact on glucose homeostasis is the first listed.
NCT05337098 reports 1 study location spanning 1 distinct geographic area - top geographies include Virginia.
Frequently Asked Questions
What is clinical trial NCT05337098 about?
NCT05337098 is a clinical study titled "Non-Nutritive Sweetener Consumption and Glucose Homeostasis in Older Adults With Prediabetes". Animal and observational research in humans suggest that specific types of non-nutritive sweeteners (NNS) may impair glycemic control. However, whether NNS consumption impacts glucose homeostasis in middle-aged/older adults with prediabetes is unknown, and potential mechanisms by which this could oc...
What is the current status of trial NCT05337098?
This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2023-04-18. Estimated completion is 2026-02-28.
What conditions does trial NCT05337098 study?
This clinical trial studies the following conditions: Insulin Sensitivity, Inflammatory Markers, Continuous Glucose Monitoring, Oral Glucose Tolerance.
What interventions are being tested in trial NCT05337098?
The interventions under investigation include: Non-Nutritive Sweetener Intake and impact on glucose homeostasis (OTHER).
Who is sponsoring clinical trial NCT05337098?
This trial is sponsored by Virginia Polytechnic Institute and State University, which has 104 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05337098 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Insulin Sensitivity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Metabolic Adaptations to Weight Loss With and Without Exercise
RECRUITING · NA
-
Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling
RECRUITING · NA
-
Countermeasures to Circadian Misalignment
RECRUITING · NA
-
Effect of Pulsatile Hormone Administration on Insulin Action
RECRUITING · NA
-
Mechanisms of Ultrasound Neuromodulation Effects in Diabetes
RECRUITING · NA
-
Effect of Physiologic Insulin Administration on Insulin Sensitivity and Cognition
RECRUITING · NA
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.