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NCT04596592 · ClinicalTrials.gov registry record
Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth
A clinical trial of Insulin Sensitivity and Gender Dysphoria, sponsored by University of Colorado, Denver.
- Recruiting
- Registry status
- 90
- Enrollment target
- 1
- Study location
NCT04596592: Recruiting study of Insulin Sensitivity and Gender Dysphoria, sponsored by University of Colorado, Denver.
NCT04596592 is a study of Insulin Sensitivity and Gender Dysphoria that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 90 participants, above the 70-participant average among 29 other Insulin Sensitivity trials with a reported enrollment target (29% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04596592, a study of Insulin Sensitivity and Gender Dysphoria, is actively recruiting participants, sponsored by University of Colorado, Denver.
- RECRUITING
- Registry status
- 90 participants
- Enrollment target
- 1
- Study location
Study Summary
To evaluate the effect of estradiol with or without a prior gonadotropin releasing hormone analogue on insulin sensitivity and vascular function in transgender females compared to cisgender controls.
Conditions Studied
Study Locations (1)
Colorado
- Children's Hospital Colorado - Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2021-02-15 |
| Est. Completion | 2026-07-31 |
What NCT04596592 shows while recruiting
NCT04596592 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 90 participants, a relatively small participant target, above the 70-participant average among 29 other Insulin Sensitivity trials with a reported enrollment target (29% higher).
The record links to 3 conditions, with Insulin Sensitivity appearing as the primary indexed condition, and to 0 interventions.
NCT04596592 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT04596592 about?
NCT04596592 is a clinical study titled "Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth". To evaluate the effect of estradiol with or without a prior gonadotropin releasing hormone analogue on insulin sensitivity and vascular function in transgender females compared to cisgender controls.
What is the current status of trial NCT04596592?
This trial is currently recruiting. The enrollment target is 90 participants. The study started on 2021-02-15. Estimated completion is 2026-07-31.
What conditions does trial NCT04596592 study?
This clinical trial studies the following conditions: Insulin Sensitivity, Gender Dysphoria, Transgenderism.
Who is sponsoring clinical trial NCT04596592?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04596592 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Insulin Sensitivity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04596592's enrollment target sits among peer trials
90 5th of 29 higher than 25 of 29 other Insulin Sensitivity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Insulin Sensitivity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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