Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Hypoxia: early-phase trial registry
11 of 40 indexed Hypoxia trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #368 of 28,707 conditions by registered trial count.
40 US clinical trials · 11 currently recruiting · #368 of 28,707 conditions by registered trial count
Hypoxia: 40 US clinical trials tracked, 11 recruiting.
Hypoxia is the subject of 40 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Nihon Kohden, running 4 of these trials.
Enrollment posture brief
Registry condition hypoxia
OPEN 11 | RECR 28% | LATE 1 | EARLY 3 | RANK #368 | SPON 4
Volume-matched condition peers
Nearest open-share peer: Kidney Cancer (28% recruiting · 69 trials)
Hypoxia lists 11 open slots (28% of 40 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Hypoxia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Hypoxia is recruiting below its size-band peers.
11 of 40 indexed trials (27.5%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Hypoxia trials is spread across many organizations.
Nihon Kohden accounts for 4 of 40 trials (10%). 31 distinct sponsors appear on at least one study for this condition label.
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Most Hypoxia trials plan to enrol fewer than 100 people.
Median target enrolment is 37 among the 40 trials that report a genuine target (sentinel values excluded). 29 of those (72.5%) plan for fewer than 100 participants.
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Hypoxia splits between interventional and observational designs.
20 interventional and 20 observational studies make up this index (50% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
40 total, page 1 of 1
Pulse Oximeter Accuracy in Healthy Humans During Hypoxia
University of California, San Francisco
NCT06142019
Optimizing Care in Critically Ill at UCHealth by Liberalizing the Target O2 in Mechanically-ventilated ICU Patients
University of Colorado, Denver
NCT06501118
End-Tidal Oxygen for Intubation in the Emergency Department
Sydney Local Health District
NCT06578468
Fetal Cerebrovascular Autoregulation in Congenital Heart Disease and Association With Neonatal Neurobehavior
University of Utah
NCT05767385
The Effects of Endotracheal Suctioning on Pain and Serum Markers
Loma Linda University
NCT06692400
Structural Modification In Supraglottic Airway Device
The Cleveland Clinic
NCT04498598
Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude
Embry-Riddle Aeronautical University
NCT07216755
Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia
University of Missouri-Columbia
NCT06417177
Intravenous Iron Effects on Performance at High Altitude
United States Army Research Institute of Environmental Medicine
NCT06686693
Novel Hypoxia Imaging for Head and Neck Cancer: Imaging Phenotype for Personalized Treatment
University of Utah
NCT06108089
Accuracy of the EvieMED Ring Pulse Oximeter in Profound Hypoxia
Movano Health
NCT06459206
Graded Exercise Hypoxia Testing
Mayo Clinic
NCT06901284
Pharmacologic Induction of Tolerance for Hypoxia & Hypothermia
University of Maryland, Baltimore
NCT06129825
Pulse Oximeter Accuracy During Stable Hypoxia Plateaus
Nihon Kohden
NCT07408388
Determination of SpO2 and PR Accuracy Specifications at Rest (71Ag_Vital-0031)
Nihon Kohden
NCT05297500
Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study)
Massachusetts General Hospital
NCT02105298
Nasotracheal Intubation With VL vs DL in Infants Trial
Children's Hospital of Philadelphia
NCT05433155
Apneic Oxygenation During Airway Management in Pediatric Patients
University of New Mexi
NCT02437864
Accuracy Of The Owlet OSS 3.0 During Standardized Stable Hypoxia Plateaus
Owlet Baby Care
NCT06850610
A Phase I Study of the Safety, Pharmacokinetics, and Anti-Tumor Activity of TH-302 in Patients With Advanced Solid Tumors
Threshold Pharmaceuticals
NCT00495144
"Reversibility of Cardiovascular Injury With CPAP Use: Mechanisms Involved"
University of Wisconsin, Madison
NCT01317329
The Effect of ECMO on the Pharmacokinetics of the Drugs and Their Clinical Efficacy
University of Pennsylvania
NCT03659513
Evaluating Sleep Quality With Emerging Technologies
Case Western Reserve University
NCT06900530
Preoxygenation With Nasal Cannula and Noninvasive Positive Pressure Ventilation
Brooke Army Medical Center
NCT03093662
Motor Plasticity, Intermittent Hypoxia and Sleep Apnea
University of Miami
NCT04017767
OM2 Abbreviated Sensor Verification
Medtronic - MITG
NCT06415799
Environmental or Nasal Cannula Oxygen for Preterm Infants Receiving Oxygen Therapy: a Randomized Cross-over Pilot Study
University of Alabama at Birmingham
NCT02794662
Ketone Esters for Optimization of Operator Performance in Hypoxia
Florida Institute for Human and Machine Cognition
NCT07065864
SpO2 Accuracy Validation of the OxySoft Sensor Via Reference CO-Oximetry Motion Study
Medtronic - MITG
NCT04559763
Accuracy of Owlet Smart Sock Sensor 3rd Generation With Profound Hypoxia
Owlet Baby Care
NCT04446247
Controlled Acute Hypoxia Study - Abbreviated Sensor Line
Medtronic - MITG
NCT02216344
Accuracy of BabySat V3 With Profound Hypoxia and Motion
Owlet Baby Care
NCT05581394
Accuracy of Pulse Oximeter With Profound Hypoxia
Sibel Health
NCT05693168
Controlled Desaturation Study for TipTraQ SpO2 Performance Validation
PranaQ Pte.
NCT06634693
SpO2 Accuracy of Noninvasive Pulse Oximeter Sensor
Stryker Sustainability Solutions
NCT05141500
Accuracy of Pulse Oximeters With Profound Hypoxia At Rest (NIHO18)
Nihon Kohden
NCT05807464
SpO2 Hypoxia Accuracy Validation Study
Nonin Medical
NCT03348189
Accuracy Validation of Belun Oxygen Saturation Pulse Oximeter FDA Submission Study
Belun Technology Company Limited
NCT03439306
SpO2 Accuracy of Noninvasive Pulse Oximeter Sensor With Motion Conditions
Stryker Sustainability Solutions
NCT06149416
Accuracy of Pulse Oximeters With Profound Hypoxia During Motion
Nihon Kohden
NCT04814342
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 1 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Hypoxia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Hypoxia trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Hypoxia page
40 registered trials, 11 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 11 Hypoxia trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Nihon Kohden sponsors the most Hypoxia trials on record, review their full trial history before evaluating a specific study. See Nihon Kohden's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Hypoxia condition card totals 40 registered trials; most-linked intervention Pulse Oximeter; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.