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2026 data Public-data reference. official source

Hypoxia

Open-data reference.

40 US clinical trials · 11 currently recruiting

Active & Recent Trials

RECRUITING 10,000 participants

Pulse Oximeter Accuracy in Healthy Humans During Hypoxia

University of California, San Francis

NCT06142019

RECRUITING NA 3,600 participants

Optimizing Care in Critically Ill at UCHealth by Liberalizing the Target O2 in Mechanically-ventilated ICU Patients

University of Colorado, Denver

NCT06501118

RECRUITING NA 1,400 participants

End-Tidal Oxygen for Intubation in the Emergency Department

Sydney Local Health District

NCT06578468

RECRUITING Phase 2 150 participants

Fetal Cerebrovascular Autoregulation in Congenital Heart Disease and Association With Neonatal Neurobehavior

University of Utah

NCT05767385

RECRUITING NA 110 participants

The Effects of Endotracheal Suctioning on Pain and Serum Markers

Loma Linda University

NCT06692400

RECRUITING NA 100 participants

Structural Modification In Supraglottic Airway Device

The Cleveland Clinic

NCT04498598

RECRUITING NA 80 participants

Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude

Embry-Riddle Aeronautical University

NCT07216755

RECRUITING Early Phase 1 75 participants

Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia

University of Missouri-Columbia

NCT06417177

RECRUITING Phase 4 24 participants

Intravenous Iron Effects on Performance at High Altitude

United States Army Research Institute of Environmental Medicine

NCT06686693

RECRUITING 20 participants

Novel Hypoxia Imaging for Head and Neck Cancer: Imaging Phenotype for Personalized Treatment

University of Utah

NCT06108089

RECRUITING 12 participants

Accuracy of the EvieMED Ring Pulse Oximeter in Profound Hypoxia

Movano Health

NCT06459206

ACTIVE NOT RECRUITING 50 participants

Graded Exercise Hypoxia Testing

Mayo Clinic

NCT06901284

ACTIVE NOT RECRUITING 50 participants

Pharmacologic Induction of Tolerance for Hypoxia & Hypothermia

University of Maryland, Baltimore

NCT06129825

ACTIVE NOT RECRUITING 48 participants

Pulse Oximeter Accuracy During Stable Hypoxia Plateaus

Nihon Kohden

NCT07408388

ACTIVE NOT RECRUITING 12 participants

Determination of SpO2 and PR Accuracy Specifications at Rest (71Ag_Vital-0031)

Nihon Kohden

NCT05297500

COMPLETED 104,000 participants

Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study)

Massachusetts General Hospital

NCT02105298

COMPLETED NA 680 participants

Nasotracheal Intubation With VL vs DL in Infants Trial

Children's Hospital of Philadelphia

NCT05433155

COMPLETED NA 360 participants

Apneic Oxygenation During Airway Management in Pediatric Patients

University of New Mexi

NCT02437864

COMPLETED NA 163 participants

Accuracy Of The Owlet OSS 3.0 During Standardized Stable Hypoxia Plateaus

Owlet Baby Care

NCT06850610

COMPLETED Phase 1 129 participants

A Phase I Study of the Safety, Pharmacokinetics, and Anti-Tumor Activity of TH-302 in Patients With Advanced Solid Tumors

Threshold Pharmaceuticals

NCT00495144

COMPLETED NA 90 participants

"Reversibility of Cardiovascular Injury With CPAP Use: Mechanisms Involved"

University of Wisconsin, Madison

NCT01317329

COMPLETED 75 participants

The Effect of ECMO on the Pharmacokinetics of the Drugs and Their Clinical Efficacy

University of Pennsylvania

NCT03659513

COMPLETED 52 participants

Evaluating Sleep Quality With Emerging Technologies

Case Western Reserve University

NCT06900530

COMPLETED NA 37 participants

Preoxygenation With Nasal Cannula and Noninvasive Positive Pressure Ventilation

Brooke Army Medical Center

NCT03093662

COMPLETED NA 30 participants

Motor Plasticity, Intermittent Hypoxia and Sleep Apnea

University of Miami

NCT04017767

COMPLETED 28 participants

OM2 Abbreviated Sensor Verification

Medtronic - MITG

NCT06415799

COMPLETED NA 25 participants

Environmental or Nasal Cannula Oxygen for Preterm Infants Receiving Oxygen Therapy: a Randomized Cross-over Pilot Study

University of Alabama at Birmingham

NCT02794662

COMPLETED NA 17 participants

Ketone Esters for Optimization of Operator Performance in Hypoxia

Florida Institute for Human and Machine Cognition

NCT07065864

COMPLETED 16 participants

SpO2 Accuracy Validation of the OxySoft Sensor Via Reference CO-Oximetry Motion Study

Medtronic - MITG

NCT04559763

COMPLETED 14 participants

Accuracy of Owlet Smart Sock Sensor 3rd Generation With Profound Hypoxia

Owlet Baby Care

NCT04446247

COMPLETED 13 participants

Controlled Acute Hypoxia Study - Abbreviated Sensor Line

Medtronic - MITG

NCT02216344

COMPLETED 12 participants

Accuracy of BabySat V3 With Profound Hypoxia and Motion

Owlet Baby Care

NCT05581394

COMPLETED NA 12 participants

Accuracy of Pulse Oximeter With Profound Hypoxia

Sibel Health

NCT05693168

COMPLETED 12 participants

Controlled Desaturation Study for TipTraQ SpO2 Performance Validation

PranaQ Pte.

NCT06634693

COMPLETED NA 12 participants

SpO2 Accuracy of Noninvasive Pulse Oximeter Sensor

Stryker Sustainability Solutions

NCT05141500

COMPLETED 12 participants

Accuracy of Pulse Oximeters With Profound Hypoxia At Rest (NIHO18)

Nihon Kohden

NCT05807464

COMPLETED 12 participants

SpO2 Hypoxia Accuracy Validation Study

Nonin Medical

NCT03348189

COMPLETED 11 participants

Accuracy Validation of Belun Oxygen Saturation Pulse Oximeter FDA Submission Study

Belun Technology Company Limited

NCT03439306

COMPLETED NA 11 participants

SpO2 Accuracy of Noninvasive Pulse Oximeter Sensor With Motion Conditions

Stryker Sustainability Solutions

NCT06149416

COMPLETED 5 participants

Accuracy of Pulse Oximeters With Profound Hypoxia During Motion

Nihon Kohden

NCT04814342

Phase Distribution

PhaseTrial count
Early Phase 1 2
Phase 2 1
Phase 4 1

Top Sponsors

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Hypoxia Trial Landscape

ClinicalTrials.gov lists 40 US studies indexed under Hypoxia, and 11 of those are currently open to recruitment — roughly 28% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Hypoxia shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 3 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Hypoxia is led by Nihon Kohden with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 40 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Hypoxia?

PlainTrial tracks 40 US clinical trials for Hypoxia, of which 11 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Hypoxia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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