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NCT06901284 · ClinicalTrials.gov registry record
Graded Exercise Hypoxia Testing
A clinical trial of Hypoxia, sponsored by Mayo Clinic.
- Active
- Registry status
- 50
- Enrollment target
- 2
- Study locations
NCT06901284: Active study of Hypoxia, sponsored by Mayo Clinic.
NCT06901284 is a study of Hypoxia that is active but no longer recruiting, run by Mayo Clinic. The registered enrollment target is 50 participants, below the 3,116-participant average among 39 other Hypoxia trials with a reported enrollment target (98% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06901284, a study of Hypoxia, is active but no longer recruiting, sponsored by Mayo Clinic.
- ACTIVE NOT RECRUITING
- Registry status
- 50 participants
- Enrollment target
- 2
- Study locations
Study Summary
The purpose of this study is to develop a single, standardized test to determine how individuals tolerate acute hypoxia in a stepwise fashion. We aim to evaluate the association between multiple factors, such as ventilatory compensation, heart rate response, acid-base changes, sex, pulmonary function, etc, which may explain why some individuals tolerate exercise in hypoxia better than others. Identifying these factors of association will inform future pharmacological and non-pharmacological attempts to combat acute hypoxic exercise.
Primary Outcome
The PaO₂/FiO₂ ratio is a widely used measure of oxygenation efficiency in the lungs. It compares the arterial oxygen partial pressure (PaO₂, measured in mmHg) to the fraction of inspired oxygen (FiO₂, expressed as a decimal). The ratio provides insight into the ability of the lungs to transfer oxygen into the bloodstream. A PaO₂/FiO₂ ratio of 300-400 is considered to be mild hypoxemia. Participants are considered as poorly tolerating hypoxia if their ratio is \<400 and good at tolerating hypoxia
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Graded Exercise Test
- DIAGNOSTIC_TEST Graded Hypoxia Exercise Test
Study Locations (2)
Minnesota
- Mayo Clinic - Rochester
- St. Mary's Hospital - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2025-04-15 |
| Est. Completion | 2028-04-24 |
What the registry record for NCT06901284 still lists
NCT06901284 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 3,116-participant average among 39 other Hypoxia trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Hypoxia appearing as the primary indexed condition, and to 2 interventions - of which Graded Exercise Test is the first listed.
NCT06901284 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT06901284 about?
NCT06901284 is a clinical study titled "Graded Exercise Hypoxia Testing". The purpose of this study is to develop a single, standardized test to determine how individuals tolerate acute hypoxia in a stepwise fashion. We aim to evaluate the association between multiple factors, such as ventilatory compensation, heart rate response, acid-base changes, sex, pulmonary functio...
What is the current status of trial NCT06901284?
This trial is currently active not recruiting. The enrollment target is 50 participants. The study started on 2025-04-15. Estimated completion is 2028-04-24.
What conditions does trial NCT06901284 study?
This clinical trial studies the following conditions: Hypoxia.
What interventions are being tested in trial NCT06901284?
The interventions under investigation include: Graded Exercise Test (DIAGNOSTIC_TEST), Graded Hypoxia Exercise Test (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT06901284?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06901284 being conducted?
This trial has 2 study locations across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hypoxia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06901284's enrollment target sits among peer trials
50 17th of 39 higher than 22 of 39 other Hypoxia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hypoxia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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