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NCT06692400 · ClinicalTrials.gov registry record · NA

The Effects of Endotracheal Suctioning on Pain and Serum Markers

A NA study of Critical Illness and Hypoxia, sponsored by Loma Linda University.

Recruiting
Registry status
NA
Development phase
110
Enrollment target
1
Study location

NCT06692400 is a NA study of Critical Illness and Hypoxia that is actively recruiting participants, run by Loma Linda University. The registered enrollment target is 110 participants, below the 3,137-participant average among 91 other Critical Illness trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06692400, a NA study of Critical Illness and Hypoxia, is actively recruiting participants, sponsored by Loma Linda University.

RECRUITING
Registry status
NA
Development phase
110 participants
Enrollment target
1
Study location

Study Summary

The goal of this experimental study is to understand if endotracheal tube (ETT) suctioning increases pain and causes stress on the body in intubated adult ICU patients. These patients are already on ventilators, which means they need suctioning to keep their airways clear, but this procedure may be uncomfortable and cause stress. The main questions this study aims to answer are: Does ETT suctioning raise pain levels as measured by the Critical-Care Pain Observation Tool (CPOT)? Does ETT suctioning increase certain chemicals in the blood (hypoxanthine, xanthine, and uric acid) that show stress and lack of oxygen in the body? Researchers will compare patients who have ETT suctioning (intervention group) with those who do not have suctioning during the study period (control group) to see if there are differences in pain and blood markers of stress. Participants will: Have pain measured before and after suctioning using the CPOT. Have blood samples taken from an existing line at three time points: 5 minutes before, 5 minutes after, and 30 minutes after suctioning. Provide demographic information (like age, gender, and diagnosis) from medical records. This research will help improve how pain is managed for ICU patients who cannot speak for themselves, potentially leading to better pain relief methods in the future.

Interventions

  • PROCEDURE endotracheal tube suctioning

Study Locations (1)

California

  • Loma Linda University Medical Center Troesh Medical Campus - Loma Linda

Trial Details

FieldValue
Enrollment Target 110 participants
Start Date 2025-01-30
Est. Completion 2026-04
Phase NA

Sponsor

Loma Linda University

237 total trials

What the Registry Record Tells You About NCT06692400

The ClinicalTrials.gov registry entry for NCT06692400 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 110 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,137-participant average among 91 other Critical Illness trials with a reported enrollment target (96% lower). The listed sponsor is Loma Linda University, which has 237 total studies on file at ClinicalTrials.gov.

The record links to 10 conditions, with Critical Illness appearing as the primary indexed condition, and to 1 intervention - of which endotracheal tube suctioning is the first listed.

NCT06692400 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT06692400 about?

NCT06692400 is a clinical study titled "The Effects of Endotracheal Suctioning on Pain and Serum Markers". The goal of this experimental study is to understand if endotracheal tube (ETT) suctioning increases pain and causes stress on the body in intubated adult ICU patients. These patients are already on ventilators, which means they need suctioning to keep their airways clear, but this procedure may be ...

What is the current status of trial NCT06692400?

This trial is currently recruiting. It is a NA study. The enrollment target is 110 participants. The study started on 2025-01-30. Estimated completion is 2026-04.

What conditions does trial NCT06692400 study?

This clinical trial studies the following conditions: Critical Illness, Hypoxia, Oxidative Stress, Mechanical Ventilation, Adult.

What interventions are being tested in trial NCT06692400?

The interventions under investigation include: endotracheal tube suctioning (PROCEDURE).

Who is sponsoring clinical trial NCT06692400?

This trial is sponsored by Loma Linda University, which has 237 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06692400 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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