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NCT07216755 · ClinicalTrials.gov registry record · NA
Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude
A NA study of Hypoxia and Healthy Adults, sponsored by Embry-Riddle Aeronautical University.
- Recruiting
- Registry status
- NA
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT07216755 is a NA study of Hypoxia and Healthy Adults that is actively recruiting participants, run by Embry-Riddle Aeronautical University. The registered enrollment target is 80 participants, below the 3,115-participant average among 39 other Hypoxia trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07216755, a NA study of Hypoxia and Healthy Adults, is actively recruiting participants, sponsored by Embry-Riddle Aeronautical University.
- RECRUITING
- Registry status
- NA
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
This study investigates whether respiratory muscle training (RMT) and dietary nitrate supplementation can improve exercise tolerance under simulated moderate altitude conditions. Exposure to reduced oxygen availability at altitude places additional strain on the cardiovascular and respiratory systems, which may limit endurance performance. By combining RMT-designed to strengthen the muscles involved in breathing-with nitrate therapy, which enhances nitric oxide availability and vascular function, this study aims to determine whether these interventions independently or synergistically improve oxygen delivery, reduce physiological strain, and enhance exercise performance. The findings will help identify non-pharmacological strategies to improve physical performance and tolerance to hypoxia in both clinical and operational environments.
Conditions Studied
Interventions
- DEVICE Respiratory Muscle Training (RMT)
- DEVICE Sham Respiratory Muscle Training
- DIETARY_SUPPLEMENT Dietary Supplement: Beetroot Juice Concentrate
- DIETARY_SUPPLEMENT placebo beverage
Study Locations (1)
Florida
- Embry-Riddle Aeronautical University - Daytona Beach
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2025-09-01 |
| Est. Completion | 2028-08-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07216755
The ClinicalTrials.gov registry entry for NCT07216755 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,115-participant average among 39 other Hypoxia trials with a reported enrollment target (97% lower). The listed sponsor is Embry-Riddle Aeronautical University, which has 2 total studies on file at ClinicalTrials.gov.
The record links to 8 conditions, with Hypoxia appearing as the primary indexed condition, and to 4 interventions - of which Respiratory Muscle Training (RMT) is the first listed.
NCT07216755 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.
Frequently Asked Questions
What is clinical trial NCT07216755 about?
NCT07216755 is a clinical study titled "Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude". This study investigates whether respiratory muscle training (RMT) and dietary nitrate supplementation can improve exercise tolerance under simulated moderate altitude conditions. Exposure to reduced oxygen availability at altitude places additional strain on the cardiovascular and respiratory system...
What is the current status of trial NCT07216755?
This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2025-09-01. Estimated completion is 2028-08-31.
What conditions does trial NCT07216755 study?
This clinical trial studies the following conditions: Hypoxia, Healthy Adults, Dietary Supplement, Exercise Training, Exercise Intolerance.
What interventions are being tested in trial NCT07216755?
The interventions under investigation include: Respiratory Muscle Training (RMT) (DEVICE), Sham Respiratory Muscle Training (DEVICE), Dietary Supplement: Beetroot Juice Concentrate (DIETARY_SUPPLEMENT), placebo beverage (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT07216755?
This trial is sponsored by Embry-Riddle Aeronautical University, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07216755 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.