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HIV Infections: early-phase trial registry
56 of 615 indexed HIV Infections trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #7 of 28,963 conditions by registered trial count.
615 US clinical trials · 56 currently recruiting · #7 of 28,963 conditions by registered trial count
HIV Infections: 615 US clinical trials tracked, 56 recruiting.
HIV Infections is the subject of 615 registered US clinical trials on ClinicalTrials.gov, 56 of them currently open to new participants. 92 are in Phase 3-4 (later-stage) and 266 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute of Allergy and Infectious Diseases (NIAID), running 195 of these trials.
Open enrollment, early-phase tilt
HIV Infections has 615 registered US clinical trials, 56 of them open to new participants right now, about 9% of the total.
- 56
- recruiting participants now
- 9%
- of trials open to enrollment
- 92
- in Phase 3-4 (later-stage)
- 195
- top sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Corpus placement: #7 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.
Key findings
What ClinicalTrials.gov does not surface for HIV Infections on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.
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HIV Infections is recruiting below its size-band peers.
56 of 615 indexed trials (9.1%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates HIV Infections research.
National Institute of Allergy and Infectious Diseases (NIAID) accounts for 195 of 615 trials (31.7%). 173 distinct sponsors appear on at least one study for this condition label.
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Typical HIV Infections enrolment sits around 100 participants.
Median target enrolment is 100 among the 543 trials that report a genuine target (sentinel values excluded). 267 of those (49.2%) plan for fewer than 100 participants.
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HIV Infections research is mostly interventional.
549 interventional and 66 observational studies make up this index (89.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
615 total, page 1 of 13
Screen Smart: Using Digital Health to Improve HIV Screening and Prevention
Children's Hospital Medical Center, Cincinnati
NCT06003192
Antiretroviral Pregnancy Registry (APR): Multi-sponsor Registry to Detect Any Major Teratogenic Effect Involving Any of the Registry Drugs When Administered to Pregnant People.
Syneos Health
NCT00404989
Keeping it LITE: Exploring HIV Risk in Vulnerable Youth With Limited Interaction and Digital Health Intervention
Hektoen Institute for Medical Research
NCT05848570
Sexual Health Advocacy for Guys - a Text Messaging-based HIV Prevention Program for Guys Who Are Into Guys
Center for Innovative Public Health Research
NCT06230367
SCOPE: Observational Study of the Consequences of the Protease Inhibitor Era
University of California, San Francisco
NCT00187512
Exploring, Predicting, and Intervening on Long-term Viral Suppression Electronically
University of California, Los Angeles
NCT06370780
IMARA for Black Male Caregivers and Girls Empowerment (IMAGE)
University of Illinois at Chicago
NCT06266416
Substance Checking Outreach and Pre-Exposure Prophylaxis (PrEP) Engagement Study
Johns Hopkins Bloomberg School of Public Health
NCT05977881
Assessing the Use of MY-RIDE, a Just-in-time Adaptive Intervention, to Improve HIV Prevention and Substance Use in Youth Experiencing Homelessness
The University of Texas Health Science Center, Houston
NCT06074354
TRAC-ER Intervention to Reduce Risky Alcohol Use and HIV Risk
University of Kentucky
NCT05576350
HIV Treatment Adherence Dose Determination Trial
University of Connecticut
NCT04577313
SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Immigrant Families
Duke University
NCT06627764
Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation
Johns Hopkins University
NCT06103370
Couples Motivational Interviewing to Reduce Drug Use and HIV Risk in Vulnerable Male Couples
Hunter College of City University of New York
NCT06307977
Comprehensive HIV and Harm Prevention Via Telehealth
University of Miami
NCT05897099
A Study to Evaluate the Effectiveness of Long-acting (LA) Cabotegravir (CAB) + Rilpivirine (RPV) LA When Given to Participants With Detectable HIV-1
ViiV Healthcare
NCT06694805
The Test-to-PrEP Study
University of Miami
NCT06927856
Cannabis, HIV and Mental Processing Systems
Washington University School of Medicine
NCT05430490
Community-based Education, Navigation, and Support Intervention for Military Veterans
New York University
NCT05343169
Comparing Mobile Health Strategies to Improve Pre-exposure Prophylaxis Use (PrEP) for HIV Prevention
Public Health Foundation Enterprises
NCT04855773
Women Focused Encounters for Resilience Independence Strength and Eudaimonia
University of California, San Diego
NCT06216600
A Setting Focus Overdose Prevention Intervention
Johns Hopkins Bloomberg School of Public Health
NCT05320835
First Time in Human Study of Long Acting VH4524184 Formulations
ViiV Healthcare
NCT06310551
Texting to Reduce Human Immunodeficiency Virus (HIV) Risk
Boston University
NCT06088277
Teamwork Makes the Dream Work
Loma Linda University
NCT05866523
Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCT
Vanderbilt University Medical Center
NCT05288790
Vaccine Immunity and Inflammation in the Aging Person Living With HIV
Hennepin Healthcare Research Institute
NCT06514547
Positive Peers Intervention Clinical Trial
MetroHealth Medical Center
NCT06388109
WiseApp for Spanish Speakers Living With HIV
Columbia University
NCT05398185
A Study to Investigate Pharmacokinetics, Safety and Tolerability of Long-Acting Cabotegravir Plus Recombinant Human Hyaluronidase PH20 in Healthy Adult Participants
ViiV Healthcare
NCT05418868
Food as Medicine for HIV and Diabetes
University of North Carolina, Chapel Hill
NCT05026723
Skeletal Muscle Energetics and Fatiguability in Older Individuals
Johns Hopkins University
NCT04142047
Peer Behavioral Activation Utilization to Improve Substance Use and HIV Outcomes in People Receiving Long Acting Injectable-PrEP/ART (PUSH)
University of Maryland, Baltimore
NCT06501781
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of VH4011499 Compared to Placebo in Adults Without HIV
ViiV Healthcare
NCT06724640
ETE Interventions in the Dental Setting
Columbia University
NCT05584501
A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study)
ViiV Healthcare
NCT07202546
People Living With HIV, Oral and Oropharyngeal Cancer, and Health Equity
University of California, San Francisco
NCT06055868
PrEP Intervention for People Who Inject Substances and Use Methamphetamine
San Francisco Department of Public Health
NCT04523519
Feasibility of HPV Testing With Mail-delivered Sample Collection Kits
University of California, San Francisco
NCT07087145
Testing a Real-time Electronic Antiretroviral Adherence Monitoring Intervention
University of Illinois at Chicago
NCT06550804
Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial)
Priscilla Hsue, MD
NCT05488431
Accelerated ART Initiation for PWHIV Who Are Out of Care
University of Missouri-Columbia
NCT06374758
Alcohol Misuse, Gut Microbial Dysbiosis and PrEP Care Continuum: Application and Efficacy of SBIRT Intervention
Shirish S Barve
NCT06005298
Effect of High-Intensity Exercise to Attenuate Cognitive Function Limitations and Train Exercise Habits in Older People Living With HIV
University of Alabama at Birmingham
NCT06013579
AURORA Study-A Transformative Approach to Support PrEP Medication Persistence
WV Health Right
NCT06072443
A Study to Investigate the Use of VH3810109 With or Without Fostemsavir (FTR) to Reduce the Size and Activity of the Viral Reservoir in People Living With HIV
ViiV Healthcare
NCT07053384
Relationship of Inflammation and Pulmonary Function to Fungal Translocation in HIV
University of Pittsburgh
NCT05502653
Virologic and Immunologic Characteristics of Severe Mpox in Persons With Advanced HIV
Centers for Disease Control and Prevention
NCT06045923
Infectious Disease (ID) Testing OUtreach in Carceral Hubs
Boston Medical Center
NCT06679751
Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People
Medical University of South Carolina
NCT05816083
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 157 |
| Phase 2 | 109 |
| Phase 3 | 69 |
| Phase 4 | 23 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
What is open for HIV Infections right now
56 recruiting of 615 indexed (9% open).
Phase mix: 92 late (III/IV) vs 266 early (I/II) (early-phase heavy).
Top sponsor: National Institute of Allergy and Infectious Diseases (NIAID) (195 trials), 9 others listed. 50 shown below, recruiting first. #7 of 28,963 conditions by registered trial count.
How open-enrollment share is computed
Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.
Frequently Asked Questions
How many clinical trials are there for HIV Infections?
PlainTrial tracks 615 US clinical trials for HIV Infections, of which 56 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for HIV Infections?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.