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NCT06514547 · ClinicalTrials.gov registry record · Phase 4
Vaccine Immunity and Inflammation in the Aging Person Living With HIV
A Phase 4 study of HIV Infections and Age, sponsored by Hennepin Healthcare Research Institute.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 250
- Enrollment target
- 1
- Study location
NCT06514547: Recruiting Phase 4 study of HIV Infections and Age, sponsored by Hennepin Healthcare Research Institute.
NCT06514547 is a Phase 4 study of HIV Infections and Age that is actively recruiting participants, run by Hennepin Healthcare Research Institute. The registered enrollment target is 250 participants, below the 445-participant average among 542 other HIV Infections trials with a reported enrollment target (44% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06514547, a Phase 4 study of HIV Infections and Age, is actively recruiting participants, sponsored by Hennepin Healthcare Research Institute.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 250 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will track immune responsiveness to conjugate pneumococcal vaccines over time to help determine how long protection from this vaccine lasts in individuals with chronic medical conditions (in this study - HIV) and with age.
Primary Outcome
Evaluate the impact of HIV status on pneumococcal vaccine immunogenicity and durability as measured pneumococcal-specific Ab concentration, memory B cell responses (frequency and phenotype) and CD4 T cell responses (frequency and phenotype) at an acute (primary comparison) and memory (secondary comparison) post-vaccination timepoints.
Conditions Studied
Interventions
- BIOLOGICAL Conjugate Pneumococcal Vaccine 20 (PCV20)
Study Locations (1)
Minnesota
- Hennepin Healthcare System - Minneapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 250 participants |
| Start Date | 2024-07-08 |
| Est. Completion | 2029-06-30 |
| Phase | Phase 4 |
What NCT06514547 shows while recruiting
NCT06514547 is an interventional study that assigns participants to a tested intervention. The registered 250 participants enrollment target is mid-sized for trials with a published cap, below the 445-participant average among 542 other HIV Infections trials with a reported enrollment target (44% lower).
The record links to 2 conditions, with HIV Infections appearing as the primary indexed condition, and to 1 intervention - of which Conjugate Pneumococcal Vaccine 20 (PCV20) is the first listed.
NCT06514547 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT06514547 about?
NCT06514547 is a clinical study titled "Vaccine Immunity and Inflammation in the Aging Person Living With HIV". This study will track immune responsiveness to conjugate pneumococcal vaccines over time to help determine how long protection from this vaccine lasts in individuals with chronic medical conditions (in this study - HIV) and with age.
What is the current status of trial NCT06514547?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 250 participants. The study started on 2024-07-08. Estimated completion is 2029-06-30.
What conditions does trial NCT06514547 study?
This clinical trial studies the following conditions: HIV Infections, Age.
What interventions are being tested in trial NCT06514547?
The interventions under investigation include: Conjugate Pneumococcal Vaccine 20 (PCV20) (BIOLOGICAL).
Who is sponsoring clinical trial NCT06514547?
This trial is sponsored by Hennepin Healthcare Research Institute, which has 63 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06514547 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for HIV Infections
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06514547's enrollment target sits among peer trials
250 139th of 542 higher than 396 of 542 other HIV Infections trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other HIV Infections trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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