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NCT06045923 · ClinicalTrials.gov registry record

Virologic and Immunologic Characteristics of Severe Mpox in Persons With Advanced HIV

A clinical trial of HIV Infections and AIDS, sponsored by Centers for Disease Control and Prevention.

Recruiting
Registry status
100
Enrollment target
1
Study location

NCT06045923: Recruiting study of HIV Infections and AIDS, sponsored by Centers for Disease Control and Prevention.

NCT06045923 is a study of HIV Infections and AIDS that is actively recruiting participants, run by Centers for Disease Control and Prevention. The registered enrollment target is 100 participants, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06045923, a study of HIV Infections and AIDS, is actively recruiting participants, sponsored by Centers for Disease Control and Prevention.

RECRUITING
Registry status
100 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to examine the extent of mpox viral spread and immunologic markers in people with advanced HIV. Study findings will enhance knowledge of mpox pathogenesis in severely immunocompromised people, which can inform treatment and prevention of severe illness and deaths associated with mpox in people with advanced HIV.

Primary Outcome

Monkeypox virus persistence in different sample types (including lesion, oropharyngeal, and rectal swabs; blood) over the course of illness

Study Locations (1)

Georgia

  • Centers for Disease Control and Prevention - Atlanta

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2023-03-17
Est. Completion 2026-10-01

What NCT06045923 shows while recruiting

NCT06045923 is an observational study that tracks outcomes without assigning an intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (78% lower).

The record links to 3 conditions, with HIV Infections appearing as the primary indexed condition, and to 0 interventions.

NCT06045923 reports a single indexed study location in Georgia.

Frequently Asked Questions

What is clinical trial NCT06045923 about?

NCT06045923 is a clinical study titled "Virologic and Immunologic Characteristics of Severe Mpox in Persons With Advanced HIV". The purpose of this study is to examine the extent of mpox viral spread and immunologic markers in people with advanced HIV. Study findings will enhance knowledge of mpox pathogenesis in severely immunocompromised people, which can inform treatment and prevention of severe illness and deaths associa...

What is the current status of trial NCT06045923?

This trial is currently recruiting. The enrollment target is 100 participants. The study started on 2023-03-17. Estimated completion is 2026-10-01.

What conditions does trial NCT06045923 study?

This clinical trial studies the following conditions: HIV Infections, AIDS, Monkeypox.

Who is sponsoring clinical trial NCT06045923?

This trial is sponsored by Centers for Disease Control and Prevention, which has 139 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06045923 being conducted?

This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for HIV Infections

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06045923's enrollment target sits among peer trials

100 267th of 542 higher than 267 of 542 other HIV Infections trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other HIV Infections trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06045923, the US trial registry maintained by the National Library of Medicine. NCT06045923 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.