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HIV Infection clinical trials
9 of 74 indexed HIV Infection trials are currently recruiting.
74 US clinical trials · 9 currently recruiting
HIV Infection is the subject of 74 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 15 are in Phase 3-4 (later-stage) and 32 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute of Allergy and Infectious Diseases (NIAID), running 12 of these trials.
The research picture
HIV Infection has 74 registered US clinical trials, 9 of them open to new participants right now, about 12% of the total.
- 9
- recruiting participants now
- 12%
- of trials open to enrollment
- 15
- in Phase 3–4 (later-stage)
- 12
- top sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Active & Recent Trials
74 total, page 2 of 2
Use of Combined Antiretroviral Therapy to Determine Sites of Persistent HIV Infection
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00001644
A Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of ABBV-181 (Budigalimab) in Adult Participants With Human Immunodeficiency Virus (HIV)-1
AbbVie
NCT04223804
The Role of Ampligen in Strategic Therapeutic Intervention (STI) of HAART
AIM ImmunoTech
NCT00035893
Immune and Viral Status of HIV-Infected Patients After Stopping Combination Antiretroviral Therapy
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00001899
Evaluation of Barriers to Postpartum Care in HIV Infected Women
The University of Texas Health Science Center, Houston
NCT01853917
Cabozantinib S-Malate in Treating Patients With Advanced Solid Tumors and Human Immunodeficiency Virus
National Cancer Institute (NCI)
NCT01822522
Boosted Lexiva With Lovaza Adjunctive Therapy in Hypertriglyceridemic, HIV-Infected Subjects
Felizarta, Franco, M.D.
NCT01010399
Influence of Antiretroviral Regimen on Immune Reconstitution in the Female Genital Tract
University of Colorado, Denver
NCT01456962
Pharmacodynamics of Intermittent IL-2 Infusions in HIV Seropositive Patients
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00001474
Phase I Protocol for the Evaluation of the Safety and Immunogenicity of Vaccination With Synthetic HIV Envelope Peptides in Patients With Early Human Immunodeficiency Virus Infection
National Cancer Institute (NCI)
NCT00001386
Physiologic Investigation of the Renin Angiotensin Aldosterone Axis in HIV
Massachusetts General Hospital
NCT01407237
Study of the Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC-HIVMAB060-00-AB (VRC01), Administered Intravenously or Subcutaneously to Healthy Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01993706
Therapeutic Intensification Plus Immunomodulation to Decrease the HIV-1 Viral Reservoir
Robert L. Murphy
NCT00976404
Androgen Effects in HIV-infected Women
Massachusetts General Hospital
NCT00095212
Continued Antiretroviral Therapy With Abacavir, Amprenavir and Efavirenz
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00001758
Technology-based Training Tool for PHAT Life
Oregon Research Behavioral Intervention Strategies
NCT05339412
Pharmacokinetics of Antiretroviral Agents in HIV-1 Infected Pregnant Women
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00006320
The Effect of Milk Thistle on the Pharmacokinetics of Indinavir
National Institutes of Health Clinical Center (CC)
NCT00011635
Phase 1 Dose Escalation Study of Autologous T-cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases in HIV-Infected Patients
Sangamo Therapeutics
NCT01044654
Evaluation of the Safety of a Polyvalent Virus in Healthy Adults
St. Jude Children's Research Hospital
NCT00187044
Reducing the Residual Reservoir of HIV-1 Infected Cells in Patients Receiving Antiretroviral Therapy
Massachusetts General Hospital
NCT02471430
SNAP: Switching Nucleoside Analogues Protocol - Lipoatrophy and Mitochondrial Function
Northwestern University
NCT00225082
Immune Activation and Drug Absorption in HIV-Infected Patients
Drexel University
NCT01845298
IMPAACT P1107: Effects of Cord Blood Transplantation With CCR5Δ32 Donor Cells on HIV Persistence
International Maternal Pediatric Adolescent AIDS Clinical Trials Group
NCT02140944
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 20 |
| Phase 2 | 12 |
| Phase 3 | 8 |
| Phase 4 | 7 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the HIV Infection Trial Landscape
74 indexed HIV Infection studies · 9 recruiting (12%).
Phase mix: 15 late (III/IV) vs 32 early (I/II).
Top sponsor: National Institute of Allergy and Infectious Diseases (NIAID) (12 trials), 9 others listed. 24 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for HIV Infection?
PlainTrial tracks 74 US clinical trials for HIV Infection, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for HIV Infection?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.