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NCT01407237 · ClinicalTrials.gov registry record
Physiologic Investigation of the Renin Angiotensin Aldosterone Axis in HIV
A clinical trial of HIV Infection, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- 30
- Enrollment target
- 1
- Study location
NCT01407237: Completed study of HIV Infection, sponsored by Massachusetts General Hospital.
NCT01407237 is a study of HIV Infection that has completed, run by Massachusetts General Hospital. The registered enrollment target is 30 participants, below the 242-participant average among 73 other HIV Infection trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01407237, a study of HIV Infection, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to see if individuals with HIV-infection, particularly those with increased belly fat, have abnormalities in the renin angiotensin aldosterone axis. Renin, angiotensin, and aldosterone are hormones that regulate salt and water balance in the body, and they may also have effects on sugar metabolism and cardiovascular health. There is some evidence that individuals with HIV-associated abdominal fat accumulation may have increased aldosterone, which may contribute to abnormalities in sugar metabolism and increased cardiovascular disease seen in HIV. The purpose of this study is the measure renin, angiotensin, and aldosterone activity, as well as other hormonal axes, in people with and without HIV infection, and with and without increased belly fat. The investigators hypothesize that aldosterone will be increased in HIV-infected individuals compared to those without HIV-infection, and that aldosterone will be further increased in HIV-infected individuals with increased abdominal fat compared to those without abdominal fat accumulation.
Conditions Studied
Interventions
- DRUG Angiotensin II Infusion
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2012-01 |
What the finished NCT01407237 record still lists
NCT01407237 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 242-participant average among 73 other HIV Infection trials with a reported enrollment target (88% lower).
The record links to 1 condition, with HIV Infection appearing as the primary indexed condition, and to 1 intervention - of which Angiotensin II Infusion is the first listed.
NCT01407237 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT01407237 about?
NCT01407237 is a clinical study titled "Physiologic Investigation of the Renin Angiotensin Aldosterone Axis in HIV". The purpose of this study is to see if individuals with HIV-infection, particularly those with increased belly fat, have abnormalities in the renin angiotensin aldosterone axis. Renin, angiotensin, and aldosterone are hormones that regulate salt and water balance in the body, and they may also have ...
What is the current status of trial NCT01407237?
This trial is currently completed. The enrollment target is 30 participants. The study started on 2012-01.
What conditions does trial NCT01407237 study?
This clinical trial studies the following conditions: HIV Infection.
What interventions are being tested in trial NCT01407237?
The interventions under investigation include: Angiotensin II Infusion (DRUG).
Who is sponsoring clinical trial NCT01407237?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01407237 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT01407237's enrollment target sits among peer trials
30 54th of 73 higher than 20 of 73 other HIV Infection trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other HIV Infection trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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