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Hepatitis C clinical trials
13 of 108 indexed Hepatitis C trials are currently recruiting.
108 US clinical trials · 13 currently recruiting
Hepatitis C is the subject of 108 registered US clinical trials on ClinicalTrials.gov, 13 of them currently open to new participants. 21 are in Phase 3-4 (later-stage) and 37 in Phase 1-2 (earlier-stage). The most active sponsor is Gilead Sciences, running 7 of these trials.
The research picture
Hepatitis C has 108 registered US clinical trials, 13 of them open to new participants right now, about 12% of the total.
- 13
- recruiting participants now
- 12%
- of trials open to enrollment
- 21
- in Phase 3–4 (later-stage)
- 7
- top sponsor: Gilead Sciences
Active & Recent Trials
108 total, page 2 of 3
Antiviral & Antifibrotic Liver Therapy in HCV + Drinkers and Non-Drinkers
Icahn School of Medicine at Mount Sinai
NCT00211848
Development and Pilot Testing of a PHCI for Emergency Department Patients Who Decline Rapid HIV/ HCV Screening
Rhode Island Hospital
NCT04137094
Phase III Daclatasvir and Sofosbuvir for Genotype 3 Chronic HCV
Bristol-Myers Squibb
NCT02032901
Safety Study of Pegylated Interferon Lambda Plus Single or 2 Direct Antiviral Agents With Ribavirin
Bristol-Myers Squibb
NCT01795911
Safety Study of Pegylated Interferon Lambda Plus Single or 2 Direct Antiviral Agents With Ribavirin
Bristol-Myers Squibb
NCT01309932
Infliximab Treatment Along With Pegylated Interferon and Ribavirin in the Treatment of Hepatitis C
Nizar Zein
NCT00512278
Prevention of De Novo HCV With Antiviral HCV Therapy Post-Liver and Post-Kidney Transplant
University of California, San Francisco
NCT03619837
A Rollover Study of BI 201335 in Combination With Pegylated Interferon-alpha and Ribavirin in Treatment-experienced Genotype 1 Hepatitis C Infected Patients
Boehringer Ingelheim
NCT01330316
A Rollover Study for Subjects Participating in the Control Arm of Study VX06-950-106, VX05-950-104 and VX05-950-104EU Whose Plasma Hepatitis C Virus (HCV) Ribonucleic Acid (RNA) Levels Did Not Respond to Therapy
Vertex Pharmaceuticals Incorporated
NCT00535847
Safety and Efficacy Study to Compare Continuous Infusion of Interferon With Standard of Care for Chronic Hepatitis C
Medtronic Corporate Technologies and New Ventures
NCT00919633
A Study of Albuferon With Ribavirin in Interferon Treatment Experienced Subjects With Chronic Hepatitis C
Human Genome Sciences
NCT00097435
Hepatitis C Education for Pregnant Women With Opiate Dependence - Phase 2
TriHealth
NCT03320889
TD-6450 SAD and MAD in Healthy Subjects
Theravance Biopharma
NCT02022306
Anticipated and Perceived Benefits Following Hepatitis C Treatment
University of North Carolina, Chapel Hill
NCT03000023
HCV Group Evaluation and Treatment Uptake (HCV GET-UP) Intervention
Montefiore Medical Center
NCT03242655
Cardiovascular Disease in HIV and Hepatitis C: Risk Outcomes After Hepatitis C Eradication
University of Maryland, Baltimore
NCT03823911
SB497115 (Oral Thrombopoietin Receptor Agonist) Versus Placebo In Adults With Thrombocytopenia Due To Hepatitis C
GlaxoSmithKline
NCT00110799
The Use of Hepatitis C Positive Livers in Hepatitis C Negative Liver Transplant Recipients
Fernanda P Silveira, MD, MS
NCT03819322
Evaluation of HepCure Toolkit to Improve Harvoni Adherence
Icahn School of Medicine at Mount Sinai
NCT02740556
Helping Empower Liver and Kidney Patients
Washington University School of Medicine
NCT03426787
Study of CTS-1027 in Combination With Pegylated Interferon and Ribavirin in Hepatitis C Virus (HCV) Null-Responders
Conatus Pharmaceuticals
NCT01051921
Efficacy of Sofosbuvir With Ribavirin Administered Pre-Transplant in Preventing Hepatitis C Virus (HCV) Recurrence Post-Transplant
Gilead Sciences
NCT01559844
GS-7977 With Ribavirin for Hepatitis C (SPARE)
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01441180
History of Hepatitis C in Volunteer Blood Donors
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00001982
Phase I Trial of Silymarin for Chronic Liver Diseases
National Center for Complementary and Integrative Health (NCCIH)
NCT00389376
Single and Multiple Dose Evaluation of ABT-072 and to Evaluate the Effect of Food on the Pharmacokinetics of ABT-072
Abbott
NCT00982826
Eliminating Hepatitis C Virus
Icahn School of Medicine at Mount Sinai
NCT03401697
Feasibility of a Hepatitis C Virus (HCV) Decision-Making Intervention Among HIV-infected Adults
University of Massachusetts, Worcester
NCT01472354
Study of FK788 in Subjects With Chronic Hepatitis C Virus Infection
Astellas Pharma
NCT00047814
Sofosbuvir (GS-7977) in Combination With PEG and Ribavirin for 12 Weeks in Treatment Experienced Subjects With Chronic HCV Infection Genotype 2 or 3
Gilead Sciences
NCT01808248
TD-6450 MAD Study in HCV Infected Subjects
Theravance Biopharma
NCT02116543
Preventing Depression in Methadone Maintenance Patients Receiving Hepatitis C Treatment - 1
National Institute on Drug Abuse (NIDA)
NCT00218556
Drug Interaction Study Between Eltrombopag and Lopinavir/Ritonavir in Healthy Adult Subjects.
GlaxoSmithKline
NCT00833378
HCV Seek, Test and Rapid Treatment for Young PWID
Weill Medical College of Cornell University
NCT03627546
New Treatment Response in People With and Without Cirrhosis From Chronic Hepatitis C
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT01888900
Study of Bavituximab in Patients With Chronic Hepatitis C Virus Infection
Peregrine Pharmaceuticals
NCT00128271
Interaction of Alcohol and Highly Active Antiretroviral Therapy (HAART) in HIV/AIDS and HIV/AIDS With Hepatitis C Virus (HCV) Co-Infection
University of California, San Francisco
NCT00879047
Evaluating the Safety of ITX 5061 in Treatment-Naive Hepatitis C (HCV)-Infected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01165359
Determining Responses to Two Different Vaccines in HIV and HCV Infected Individuals
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00393276
Proof of Concept Study for Safety and Efficacy of EDP239 in Hepatitis C Subjects
Enanta Pharmaceuticals
NCT01856426
Potential for Drug-drug Interactions Between Boceprevir and Etravirine in HIV/Hepatitis C Virus Negative Volunteers
University of Colorado, Denver
NCT01427504
Rapid Hepatitis C Elimination Trial- A Pilot Study of Daclatasvir/Asunaprevir/BMS-791325 With or Without Ribavirin To Treat Hepatitis C Virus
Timothy Morgan, MD
NCT02098616
Open-Label Hepatic Impairment Study
Gilead Sciences
NCT01497327
Treatment of Hepatitis C in Hemophilic Patients With HIV
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00055341
Treatment of Acute Hepatitis C Virus in HIV Co-Infection
University of California, San Francisco
NCT00845676
Cross-Over Study to Assess the Cardiovascular Effects of GSK2336805
GlaxoSmithKline
NCT01424540
A Study to Examine the Effects of Telaprevir on the Pharmacokinetics of Cyclosporine and Tacrolimus in Healthy Adults
Vertex Pharmaceuticals Incorporated
NCT01038167
Efficacy of Actos Lipitor Pegasys & Ribavirin in CHC GT 1 Patients Who Relapsed or Nonresponded to Peg/Riba
Brooke Army Medical Center
NCT00926614
Non-invasive Biomarkers of Fibrosis in Pediatric Liver Diseases
Baylor College of Medicine
NCT01988753
Dose Finding Trial of Rosuvastatin and Atorvastatin Versus Hepatitis C
Bader, Ted, M.D.
NCT00446940
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 14 |
| Phase 2 | 23 |
| Phase 3 | 11 |
| Phase 4 | 10 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Hepatitis C Trial Landscape
108 indexed Hepatitis C studies · 13 recruiting (12%).
Phase mix: 21 late (III/IV) vs 37 early (I/II).
Top sponsor: Gilead Sciences (7 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Hepatitis C?
PlainTrial tracks 108 US clinical trials for Hepatitis C, of which 13 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Hepatitis C?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.