Theravance Biopharma

Closed portfolio with an early-phase archive tilt

According to ClinicalTrials.gov-derived indexes, Theravance Biopharma sits in the top decile of US sponsors by registered trial count (#448 of 15,742 sponsors by registered trial count).

38 total trials none currently recruiting 31 completed early-phase tilt top decile by trial count

Theravance Biopharma: 38 sponsored US clinical trials, none currently recruiting.

Theravance Biopharma sponsors 38 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 31 completed. 5 of these trials are in Phase 3-4 (later-stage) and 32 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy Adults, Elderly Subjects, with 2 trials.

Top-decile sponsor footprint

Theravance Biopharma ranks in the top decile of sponsors by registered trial count (#448 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 49/100

31 of 37 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (83.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Indexed trials (enrollment closed)

38 total, page 1 of 1

ACTIVE NOT RECRUITING Phase 3

Phase 3 Efficacy and Durability of Ampreloxetine for the Treatment of Symptomatic nOH in Participants With Multiple System Atrophy

NCT05696717

COMPLETED Phase 4

Phase 4 COPD and Suboptimal Inspiratory Flow Rate

NCT05165485

COMPLETED Phase 1

TD-0903 Pharmacokinetics Study in Healthy Participants With Supplemental Oxygenation

NCT05091723

COMPLETED

Comparison of Viral Particle Dispersion Following Administration of an MDI or Nebulizer in Subjects With COVID-19

NCT04681079

COMPLETED Phase 1

Thorough QT Study to Evaluate Ampreloxetine in Healthy Subjects

NCT04688632

COMPLETED Phase 1

Single Dose Bioavailability and Ethnobridging PK Study in Healthy Subjects

NCT04587713

TERMINATED Phase 2

TD-1473 Long-Term Safety (LTS) Ulcerative Colitis (UC) Study

NCT03920254

COMPLETED Phase 2

TD-0903 for ALI Associated With COVID-19

NCT04402866

COMPLETED Phase 1

Effect of Hepatic Impairment on the Pharmacokinetics of a Single Dose of TD-9855

NCT04200573

TERMINATED Phase 3

Phase 3 Open-Label Extension Study of TD-9855 for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure

NCT04095793

COMPLETED Phase 1

Single and Multiple Ascending Dose, First-in- Human Study in Healthy Subjects

NCT04044339

TERMINATED Phase 2

Efficacy & Safety of TD-1473 in Ulcerative Colitis

NCT03758443

TERMINATED Phase 3

Phase 3 Clinical Effect Durability of TD-9855 for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure

NCT03829657

COMPLETED Phase 3

Clinical Effect of Ampreloxetine (TD-9855) for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure

NCT03750552

COMPLETED Phase 1

Multiple Dose Ethnobridging PK Study in Healthy Subjects

NCT03750565

TERMINATED Phase 2

Efficacy and Safety of TD-1473 in Crohn's Disease

NCT03635112

COMPLETED Phase 1

Food-effect, Drug-Drug Interaction (DDI), and Formulation Bridging Study

NCT03555617

COMPLETED Phase 1

Drug-Drug Interaction (DDI) Study for TD-9855

NCT03432793

COMPLETED Phase 1

TD-1473 Absorption, Distribution, Metabolism and Excretion (ADME) Study in Healthy Male Subjects

NCT03408470

COMPLETED Phase 2

TD-9855 Phase 2 in Neurogenic Orthostatic Hypotension (nOH)

NCT02705755

COMPLETED Phase 1

TD-3504 SAD in Healthy Subjects and Subjects With Ulcerative Colitis (UC)

NCT03103412

COMPLETED Phase 1

Multiple Ascending Dose Study of TD-1439 in Healthy Adult and Elderly Subjects

NCT02954263

COMPLETED Phase 1

TD-1473 for Active Ulcerative Colitis (UC)

NCT02818686

COMPLETED Phase 1

Single Ascending Dose Study of TD-1439 in Healthy Subjects

NCT02903095

COMPLETED Phase 1

Multiple Ascending Dose Study of TD-0714 in Healthy and Elderly Subjects

NCT02709928

COMPLETED Phase 1

SAD and MAD Study to Evaluate Safety, Tolerability, and Pharmacokinetics (PK) of TD-1473 in Healthy Subjects

NCT02657122

COMPLETED Phase 1

Single Ascending Dose Study of TD-0714 in Healthy Subjects

NCT02639078

COMPLETED Phase 1

TD-6450 MAD Study in HCV Infected Subjects

NCT02116543

COMPLETED Phase 1

TD-6450 SAD and MAD in Healthy Subjects

NCT02022306

COMPLETED Phase 1

TD-9855 Mass Balance Study

NCT01924143

COMPLETED Phase 1

TD-1607 MAD Study in Healthy Subjects

NCT01949103

COMPLETED Phase 1

TD-1607 SAD Study in Healthy Subjects

NCT01791049

COMPLETED Phase 2

Phase 2 Study of Velusetrag in Diabetic or Idiopathic Gastroparesis

NCT01718938

COMPLETED Phase 2

Phase 2 Study of TD-9855 to Treat Fibromyalgia

NCT01693692

TERMINATED Phase 1

A Phase 1, Multiple Intravenous Dose Study to Examine Safety, Tolerability, and PK of Intravenous TD-8954, a 5-HT4 Receptor Agonist, in Healthy Subjects

NCT01644240

COMPLETED Phase 2

A Study of TD-9855 in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)

NCT01458340

COMPLETED Phase 2

A Study of TD-1211 in Subjects With Opioid-Induced Constipation (OIC)

NCT01401985

COMPLETED Phase 2

TD-1792 in Gram-positive Complicated Skin and Skin Structure Infection

NCT00442832

How the Theravance Biopharma early-phase archive is shaped

38 indexed studies, none listed as recruiting (0% open); 31 completed (82%).

Phase mix: 5 late (III/IV) vs 32 early (I/II) (early-phase heavy).

Top condition: Healthy Adults, Elderly Subjects (2 trials), 9 others listed.

How to read a closed sponsor archive

When recruiting_count is zero, the indexed set is completed or otherwise not open. Phase tilt still describes where archived studies sat on the investigational pathway. Re-check ClinicalTrials.gov before acting.

Theravance Biopharma: archived-pipeline peers nationwide

Peers matched on 38 indexed studies with no current recruiting: volume and archive shape, not condition overlap.

Theravance Biopharma sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 010203040 0%5%10%15% Total trials Recruiting share Theravance BiopharmaAcerta PharmaAstex PharmaceuticalsCorewell Health WestDePuy Orthopaedics10xBio22nd Century Group23andMe3-C Institute for Social Development
Theravance Biopharma sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Theravance Biopharma sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 38 archived trials

Sponsors with similar archive density (± trial count)

What to do with this Theravance Biopharma page

38 registered trials is a research-attention snapshot, not an endorsement of Theravance Biopharma or any single study.

  • None of Theravance Biopharma's trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • Healthy Adults, Elderly Subjects is the condition Theravance Biopharma studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy Adults, Elderly Subjects trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Theravance Biopharma pipeline card: 38 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.