Theravance Biopharma

Closed portfolio with an early-phase archive tilt

According to ClinicalTrials.gov-derived indexes, Theravance Biopharma sits in the top decile of US sponsors by registered trial count (#448 of 15,742 sponsors by registered trial count).

38 total trials none currently recruiting 31 completed early-phase tilt top decile by trial count

Theravance Biopharma: 38 sponsored US clinical trials, none currently recruiting.

Theravance Biopharma sponsors 38 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 31 completed. 5 of these trials are in Phase 3-4 (later-stage) and 32 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy Adults, Elderly Subjects, with 2 trials.

Top-decile sponsor footprint

Theravance Biopharma ranks in the top decile of sponsors by registered trial count (#448 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 49/100

31 of 37 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (83.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Indexed trials (enrollment closed)

38 total, page 1 of 1

ACTIVE NOT RECRUITING Phase 3

Phase 3 Efficacy and Durability of Ampreloxetine for the Treatment of Symptomatic nOH in Participants With Multiple System Atrophy

NCT05696717

COMPLETED Phase 4

Phase 4 COPD and Suboptimal Inspiratory Flow Rate

NCT05165485

COMPLETED Phase 1

TD-0903 Pharmacokinetics Study in Healthy Participants With Supplemental Oxygenation

NCT05091723

COMPLETED

Comparison of Viral Particle Dispersion Following Administration of an MDI or Nebulizer in Subjects With COVID-19

NCT04681079

COMPLETED Phase 1

Thorough QT Study to Evaluate Ampreloxetine in Healthy Subjects

NCT04688632

COMPLETED Phase 1

Single Dose Bioavailability and Ethnobridging PK Study in Healthy Subjects

NCT04587713

TERMINATED Phase 2

TD-1473 Long-Term Safety (LTS) Ulcerative Colitis (UC) Study

NCT03920254

COMPLETED Phase 2

TD-0903 for ALI Associated With COVID-19

NCT04402866

COMPLETED Phase 1

Effect of Hepatic Impairment on the Pharmacokinetics of a Single Dose of TD-9855

NCT04200573

TERMINATED Phase 3

Phase 3 Open-Label Extension Study of TD-9855 for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure

NCT04095793

COMPLETED Phase 1

Single and Multiple Ascending Dose, First-in- Human Study in Healthy Subjects

NCT04044339

TERMINATED Phase 2

Efficacy & Safety of TD-1473 in Ulcerative Colitis

NCT03758443

TERMINATED Phase 3

Phase 3 Clinical Effect Durability of TD-9855 for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure

NCT03829657

COMPLETED Phase 3

Clinical Effect of Ampreloxetine (TD-9855) for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure

NCT03750552

COMPLETED Phase 1

Multiple Dose Ethnobridging PK Study in Healthy Subjects

NCT03750565

TERMINATED Phase 2

Efficacy and Safety of TD-1473 in Crohn's Disease

NCT03635112

COMPLETED Phase 1

Food-effect, Drug-Drug Interaction (DDI), and Formulation Bridging Study

NCT03555617

COMPLETED Phase 1

Drug-Drug Interaction (DDI) Study for TD-9855

NCT03432793

COMPLETED Phase 1

TD-1473 Absorption, Distribution, Metabolism and Excretion (ADME) Study in Healthy Male Subjects

NCT03408470

COMPLETED Phase 2

TD-9855 Phase 2 in Neurogenic Orthostatic Hypotension (nOH)

NCT02705755

COMPLETED Phase 1

TD-3504 SAD in Healthy Subjects and Subjects With Ulcerative Colitis (UC)

NCT03103412

COMPLETED Phase 1

Multiple Ascending Dose Study of TD-1439 in Healthy Adult and Elderly Subjects

NCT02954263

COMPLETED Phase 1

TD-1473 for Active Ulcerative Colitis (UC)

NCT02818686

COMPLETED Phase 1

Single Ascending Dose Study of TD-1439 in Healthy Subjects

NCT02903095

COMPLETED Phase 1

Multiple Ascending Dose Study of TD-0714 in Healthy and Elderly Subjects

NCT02709928

COMPLETED Phase 1

SAD and MAD Study to Evaluate Safety, Tolerability, and Pharmacokinetics (PK) of TD-1473 in Healthy Subjects

NCT02657122

COMPLETED Phase 1

Single Ascending Dose Study of TD-0714 in Healthy Subjects

NCT02639078

COMPLETED Phase 1

TD-6450 MAD Study in HCV Infected Subjects

NCT02116543

COMPLETED Phase 1

TD-6450 SAD and MAD in Healthy Subjects

NCT02022306

COMPLETED Phase 1

TD-9855 Mass Balance Study

NCT01924143

COMPLETED Phase 1

TD-1607 MAD Study in Healthy Subjects

NCT01949103

COMPLETED Phase 1

TD-1607 SAD Study in Healthy Subjects

NCT01791049

COMPLETED Phase 2

Phase 2 Study of Velusetrag in Diabetic or Idiopathic Gastroparesis

NCT01718938

COMPLETED Phase 2

Phase 2 Study of TD-9855 to Treat Fibromyalgia

NCT01693692

TERMINATED Phase 1

A Phase 1, Multiple Intravenous Dose Study to Examine Safety, Tolerability, and PK of Intravenous TD-8954, a 5-HT4 Receptor Agonist, in Healthy Subjects

NCT01644240

COMPLETED Phase 2

A Study of TD-9855 in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)

NCT01458340

COMPLETED Phase 2

A Study of TD-1211 in Subjects With Opioid-Induced Constipation (OIC)

NCT01401985

COMPLETED Phase 2

TD-1792 in Gram-positive Complicated Skin and Skin Structure Infection

NCT00442832

How the Theravance Biopharma early-phase archive is shaped

38 indexed studies, none listed as recruiting (0% open); 31 completed (82%).

Phase mix: 5 late (III/IV) vs 32 early (I/II) (early-phase heavy).

Top condition: Healthy Adults, Elderly Subjects (2 trials), 9 others listed.

How to read a closed sponsor archive

When recruiting_count is zero, the indexed set is completed or otherwise not open. Phase tilt still describes where archived studies sat on the investigational pathway. Re-check ClinicalTrials.gov before acting.

Theravance Biopharma: archived-pipeline peers nationwide

Peers matched on 38 indexed studies with no current recruiting: volume and archive shape, not condition overlap.

Theravance Biopharma sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 010203040 0%5%10%15% Total trials Recruiting share Theravance BiopharmaAcerta PharmaAstex PharmaceuticalsCorewell Health WestDePuy Orthopaedics10xBio22nd Century Group23andMe3-C Institute for Social Development
Theravance Biopharma sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Theravance Biopharma sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 38 archived trials

Sponsors with similar archive density (± trial count)

What to do with this Theravance Biopharma page

38 registered trials is a research-attention snapshot, not an endorsement of Theravance Biopharma or any single study.

  • None of Theravance Biopharma's trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • Healthy Adults, Elderly Subjects is the condition Theravance Biopharma studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy Adults, Elderly Subjects trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Theravance Biopharma pipeline card: 38 registered trials from official public datasets.Report a data error.