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COMPLETED Phase 2

Study of CTS-1027 in Combination With Pegylated Interferon and Ribavirin in Hepatitis C Virus (HCV) Null-Responders

NCT01051921 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to determine if the combination treatment of CTS-1027, pegylated interferon and ribavirin can improve the response rates in HCV patients who did not previously respond to pegylated interferon and ribavirin therapy.

Conditions Studied

Interventions

  • DRUG Ribavirin
  • DRUG CTS-1027
  • DRUG Pegylated interferon

Study Locations (15)

California

  • Scripps Clinic — La Jolla
  • VA Medical Center, San Diego — San Diego

Colorado

  • University of Colorado Health Science Center — Denver
  • South Denver Gastroenterology — Englewood

Texas

  • Advanced Liver Therapies - Baylor College of Medicine — Houston
  • VA Medical Center, Houston — Houston

Georgia

  • Digestive Healthcare of Georgia — Atlanta

Louisiana

  • Tulane University Health Sciences Center — New Orleans

Michigan

  • Henry Ford Medical Center-Columbus — Novi

Minnesota

  • MN Clinical Research Center — Plymouth

Missouri

  • St. Louis University — St Louis

Trial Details

FieldValue
Enrollment Target 67 participants
Start Date 2010-01
Est. Completion 2011-12
Phase Phase 2

Sponsor

Conatus Pharmaceuticals

4 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT01051921

The ClinicalTrials.gov registry entry for NCT01051921 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 67 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Conatus Pharmaceuticals, which has 4 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Hepatitis C appearing as the primary indexed condition, and to 3 interventions — of which Ribavirin is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT01051921 reports 15 study locations spanning 12 distinct geographic areas — top geographies include California, Colorado, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT01051921 about?

NCT01051921 is a clinical study titled "Study of CTS-1027 in Combination With Pegylated Interferon and Ribavirin in Hepatitis C Virus (HCV) Null-Responders". The purpose of this study is to determine if the combination treatment of CTS-1027, pegylated interferon and ribavirin can improve the response rates in HCV patients who did not previously respond to pegylated interferon and ribavirin therapy.

What is the current status of trial NCT01051921?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 67 participants. The study started on 2010-01. Estimated completion is 2011-12.

What conditions does trial NCT01051921 study?

This clinical trial studies the following conditions: Hepatitis C. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT01051921?

The interventions under investigation include: Ribavirin (DRUG), CTS-1027 (DRUG), Pegylated interferon (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT01051921?

This trial is sponsored by Conatus Pharmaceuticals, which has 4 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT01051921 being conducted?

This trial has 15 study locations across California, Colorado, Georgia, Louisiana, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial