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Prevention of De Novo HCV With Antiviral HCV Therapy Post-Liver and Post-Kidney Transplant
NCT03619837 · View on ClinicalTrials.gov ↗
Study Summary
In this study, subjects that do not have Hepatitis C virus (HCV) will be transplanted with livers or kidneys from donors who do have HCV. Medications that are used to treat HCV will be given to the study subjects shortly after transplant to protect them from developing the problems HCV can cause to the liver.
Conditions Studied
Interventions
- DRUG Sofosbuvir/Velpatasvir
- DRUG Sofosbuvir/Velpatasvir/Voxilaprevir
Study Locations (6)
Texas
- Baylor University Medical Center - Dallas — Dallas
- Houston Methodist Hospital — Houston
California
- University of California, San Francisco — San Francisco
Colorado
- University of Colorado Denver — Aurora
Georgia
- Piedmont Research Institute — Atlanta
New York
- Columbia University — New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 122 participants |
| Start Date | 2018-07-15 |
| Est. Completion | 2020-08-13 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03619837
The ClinicalTrials.gov registry entry for NCT03619837 describes a study currently listed as completed. It is categorized as Phase 4, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 122 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Francis, which has 1,574 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Hepatitis C appearing as the primary indexed condition, and to 2 interventions — of which Sofosbuvir/Velpatasvir is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT03619837 reports 6 study locations spanning 5 distinct geographic areas — top geographies include Texas, California, Colorado. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT03619837 about?
NCT03619837 is a clinical study titled "Prevention of De Novo HCV With Antiviral HCV Therapy Post-Liver and Post-Kidney Transplant". In this study, subjects that do not have Hepatitis C virus (HCV) will be transplanted with livers or kidneys from donors who do have HCV. Medications that are used to treat HCV will be given to the study subjects shortly after transplant to protect them from developing the problems HCV can cause to ...
What is the current status of trial NCT03619837?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 122 participants. The study started on 2018-07-15. Estimated completion is 2020-08-13.
What conditions does trial NCT03619837 study?
This clinical trial studies the following conditions: Hepatitis C, Transplantation Disease Transmission. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT03619837?
The interventions under investigation include: Sofosbuvir/Velpatasvir (DRUG), Sofosbuvir/Velpatasvir/Voxilaprevir (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT03619837?
This trial is sponsored by University of California, San Francis, which has 1,574 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT03619837 being conducted?
This trial has 6 study locations across California, Colorado, Georgia, New York, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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