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ClinicalTrials.gov 6 recruiting now early-phase tilt small index

Hematologic Diseases: early-phase trial registry

6 of 18 indexed Hematologic Diseases trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #953 of 28,707 conditions by registered trial count.

18 US clinical trials · 6 currently recruiting · #953 of 28,707 conditions by registered trial count

Hematologic Diseases: 18 US clinical trials tracked, 6 recruiting.

Hematologic Diseases is the subject of 18 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Vertex Pharmaceuticals Incorporated, running 2 of these trials.

Enrollment posture brief

Registry condition hematologic-diseases

OPEN 6 | RECR 33% | LATE 3 | EARLY 5 | RANK #953 | SPON 2

Nearest open-share peer: Adherence, Treatment (33% recruiting · 6 trials)

Hematologic Diseases (this)33%Arrhythmias, Cardiac27.8%Androgenetic Alopecia16.7%Anemia, Sickle Cell16.7%Acquired Immunodeficiency Sy5.6%
Open-enrollment share among volume-matched conditions near Hematologic Diseases

Hematologic Diseases lists 6 open slots (33% of 18 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Hematologic Diseases on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Hematologic Diseases is recruiting below its size-band peers.

    6 of 18 indexed trials (33.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Hematologic Diseases trials is spread across many organizations.

    Vertex Pharmaceuticals Incorporated accounts for 2 of 18 trials (11.1%). 16 distinct sponsors appear on at least one study for this condition label.

  3. Typical Hematologic Diseases enrolment sits around 81 participants.

    Median target enrolment is 81 among the 18 trials that report a genuine target (sentinel values excluded). 10 of those (55.6%) plan for fewer than 100 participants.

  4. Hematologic Diseases research is mostly interventional.

    13 interventional and 5 observational studies make up this index (72.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 22Phase 33

Open and recent trials

18 total, page 1 of 1

RECRUITING 2,000 participants

The Use of Residual De-identified Specimens and/or Samples From Patients for Clinical Research

Invivoscribe

NCT06222164

RECRUITING NA 700 participants

HEME Home Transfusion Program

Dana-Farber Cancer Institute

NCT06487247

RECRUITING NA 204 participants

Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Young Adults

Alice Bertaina

NCT04249830

RECRUITING Phase 1 81 participants

A Study to Evaluate the Safety, PK/PD of (OriCAR-017) in Subjects With RR/MM - RIGEL Study

OriCell Therapeutics Co.

NCT06271252

RECRUITING Phase 3 26 participants

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

Vertex Pharmaceuticals Incorporated

NCT05477563

RECRUITING Phase 1 22 participants

Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Adults With T-allo10 Cells Addback

Porteus, Matthew, MD

NCT04640987

ACTIVE NOT RECRUITING 32,658 participants

Gulf Long-Term Follow-Up Study

National Institute of Environmental Health Sciences (NIEHS)

NCT01287000

ACTIVE NOT RECRUITING NA 230 participants

Multimodal Sexual Dysfunction Intervention In HCT

Massachusetts General Hospital

NCT03803696

ACTIVE NOT RECRUITING Phase 1 43 participants

Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation

University of Michigan Rogel Cancer Center

NCT03842696

ACTIVE NOT RECRUITING Phase 3 16 participants

Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Transfusion-Dependent β-Thalassemia (TDT)

Vertex Pharmaceuticals Incorporated

NCT05356195

COMPLETED 1,452 participants

Evaluation, Treatment, and Training for Patients With Blood Disorders

National Heart, Lung, and Blood Institute (NHLBI)

NCT00001397

COMPLETED NA 279 participants

Implementing an Individualized Pain Plan (IPP) for ED Treatment of VOE's in Sickle Cell Disease

Duke University

NCT04584528

COMPLETED Phase 2 182 participants

A Randomized Trial of Antithymocyte Globulin Versus Cyclosporine to Treat the Cytopenia of Myelodysplastic Syndrome

National Institutes of Health Clinical Center (CC)

NCT00001839

COMPLETED Phase 3 65 participants

A Prospective, Randomized, Phase III Trial of FLAC (5-Fluorouracil, Leucovorin, Adriamycin, Cytoxan) Chemotherapy With GM-CSF (Granulocyte-Macrophage Colony-Stimulating Factor) Versus PIXY 321 in Advanced Breast Cancer

National Cancer Institute (NCI)

NCT00001338

COMPLETED Phase 2 30 participants

Cord Blood Transplantation for Sickle Cell Anemia and Thalassemia

National Heart, Lung, and Blood Institute (NHLBI)

NCT00029380

COMPLETED 30 participants

HLA Matching - Unrelated Umbilical Cord Blood Transplantation

Ann & Robert H Lurie Children's Hospital of Chicago

NCT00179946

COMPLETED 20 participants

Patient-Reported Outcomes Version of Common Terminology Criteria (CTCPRO) Cognitive Debriefing

M.D. Anderson Cancer Center

NCT00909207

COMPLETED NA 10 participants

Granulocyte Colony Stimulating Factor (G-CSF) for Bone Marrow Transplant (BMT)

Emory University

NCT00231309

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 2
Phase 3 3

Named interventions

Most-linked intervention names on Hematologic Diseases records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

CTX001 Biological
2 trials
Cyclosporine Drug
2 trials
Allogeneic Stem Cell Transplant Biological
2 trials
HLA typing Procedure
1 trials
Electronic Health Record (EHR) Embedded Individualized Pain Plan (IPP) Other
1 trials
Antithymocyte globulin Drug
1 trials
Granulocyte Colony Stimulating Factor Drug
1 trials
FLAC chemotherapy with GM-CSF Drug
1 trials

US sites by state

Facility locations filed on Hematologic Diseases trials. A trial with sites in several states counts in each.

North Carolina 5 trials
California 5 trials
Tennessee 4 trials
Georgia 4 trials
New York 3 trials
Maryland 3 trials
Massachusetts 3 trials
Illinois 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Hematologic Diseases page

18 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Hematologic Diseases condition card totals 18 registered trials; most-linked intervention CTX001; top US site state North Carolina. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.