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ClinicalTrials.gov 6 recruiting now official registry

Hematologic Diseases clinical trials

6 of 18 indexed Hematologic Diseases trials are currently recruiting.

18 US clinical trials · 6 currently recruiting

Hematologic Diseases is the subject of 18 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Vertex Pharmaceuticals Incorporated, running 2 of these trials.

The research picture

Hematologic Diseases has 18 registered US clinical trials, 6 of them open to new participants right now, about 33% of the total.

6
recruiting participants now
33%
of trials open to enrollment
3
in Phase 3–4 (later-stage)
2
top sponsor: Vertex Pharmaceuticals Incorporated
Phase 13Phase 22Phase 33

Active & Recent Trials

18 total, page 1 of 1

RECRUITING 2,000 participants

The Use of Residual De-identified Specimens and/or Samples From Patients for Clinical Research

Invivoscribe

NCT06222164

RECRUITING NA 700 participants

HEME Home Transfusion Program

Dana-Farber Cancer Institute

NCT06487247

RECRUITING NA 204 participants

Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Young Adults

Alice Bertaina

NCT04249830

RECRUITING Phase 1 81 participants

A Study to Evaluate the Safety, PK/PD of (OriCAR-017) in Subjects With RR/MM - RIGEL Study

OriCell Therapeutics Co.

NCT06271252

RECRUITING Phase 3 26 participants

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

Vertex Pharmaceuticals Incorporated

NCT05477563

RECRUITING Phase 1 22 participants

Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Adults With T-allo10 Cells Addback

Porteus, Matthew, MD

NCT04640987

ACTIVE NOT RECRUITING 32,658 participants

Gulf Long-Term Follow-Up Study

National Institute of Environmental Health Sciences (NIEHS)

NCT01287000

ACTIVE NOT RECRUITING NA 230 participants

Multimodal Sexual Dysfunction Intervention In HCT

Massachusetts General Hospital

NCT03803696

ACTIVE NOT RECRUITING Phase 1 43 participants

Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation

University of Michigan Rogel Cancer Center

NCT03842696

ACTIVE NOT RECRUITING Phase 3 16 participants

Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Transfusion-Dependent β-Thalassemia (TDT)

Vertex Pharmaceuticals Incorporated

NCT05356195

COMPLETED 1,452 participants

Evaluation, Treatment, and Training for Patients With Blood Disorders

National Heart, Lung, and Blood Institute (NHLBI)

NCT00001397

COMPLETED NA 279 participants

Implementing an Individualized Pain Plan (IPP) for ED Treatment of VOE's in Sickle Cell Disease

Duke University

NCT04584528

COMPLETED Phase 2 182 participants

A Randomized Trial of Antithymocyte Globulin Versus Cyclosporine to Treat the Cytopenia of Myelodysplastic Syndrome

National Institutes of Health Clinical Center (CC)

NCT00001839

COMPLETED Phase 3 65 participants

A Prospective, Randomized, Phase III Trial of FLAC (5-Fluorouracil, Leucovorin, Adriamycin, Cytoxan) Chemotherapy With GM-CSF (Granulocyte-Macrophage Colony-Stimulating Factor) Versus PIXY 321 in Advanced Breast Cancer

National Cancer Institute (NCI)

NCT00001338

COMPLETED Phase 2 30 participants

Cord Blood Transplantation for Sickle Cell Anemia and Thalassemia

National Heart, Lung, and Blood Institute (NHLBI)

NCT00029380

COMPLETED 30 participants

HLA Matching - Unrelated Umbilical Cord Blood Transplantation

Ann & Robert H Lurie Children's Hospital of Chicago

NCT00179946

COMPLETED 20 participants

Patient-Reported Outcomes Version of Common Terminology Criteria (CTCPRO) Cognitive Debriefing

M.D. Anderson Cancer Center

NCT00909207

COMPLETED NA 10 participants

Granulocyte Colony Stimulating Factor (G-CSF) for Bone Marrow Transplant (BMT)

Emory University

NCT00231309

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 2
Phase 3 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Hematologic Diseases Trial Landscape

18 indexed Hematologic Diseases studies · 6 recruiting (33%).

Phase mix: 3 late (III/IV) vs 5 early (I/II).

Top sponsor: Vertex Pharmaceuticals Incorporated (2 trials), 9 others listed. 18 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Hematologic Diseases?

PlainTrial tracks 18 US clinical trials for Hematologic Diseases, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Hematologic Diseases?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.