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NCT00231309 · ClinicalTrials.gov registry record · NA

Granulocyte Colony Stimulating Factor (G-CSF) for Bone Marrow Transplant (BMT)

A NA study of Hematologic Malignancies and Hematologic Diseases, sponsored by Emory University.

Completed
Registry status
NA
Development phase
10
Enrollment target
1
Study location

NCT00231309 is a NA study of Hematologic Malignancies and Hematologic Diseases that has completed, run by Emory University. The registered enrollment target is 10 participants, below the 2,712-participant average among 45 other Hematologic Malignancies trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00231309, a NA study of Hematologic Malignancies and Hematologic Diseases, has completed, sponsored by Emory University.

COMPLETED
Registry status
NA
Development phase
10 participants
Enrollment target
1
Study location

Study Summary

The major purpose of this study is to evaluate the curative potential of white cell growth hormone (G-CSF)-stimulated bone marrow cells in allogeneic bone marrow transplants. Patients with cancers or blood diseases, who have poor potential for a cure with standard treatment, will be able to participate in the study. Donors will receive the white cell growth hormone (G-CSF) as a shot (injection) in their arm once a day for three days before they donate their bone marrow cells. Total body irradiation and/or chemotherapy will be given first to prepare the patient's body for the infusion of new bone marrow cells from the donor. Two medicines (cyclosporine and methotrexate) will be used to prevent the new bone marrow cells (graft) from attacking the patient's body (host) (graft-versus-host disease; GVHD). Certain safety checkpoints were built into the study if unwanted/unexpected events were to occur. If the outcomes appear better than could be expected, this will provide a bridge to extend this current approach for other innovative therapies.

Interventions

  • DRUG Granulocyte Colony Stimulating Factor

Study Locations (1)

Georgia

  • Children's Healthcare of Atlanta/Emory University - Atlanta

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2003-07
Est. Completion 2011-11
Phase NA

Sponsor

Emory University

1,208 total trials

What the Registry Record Tells You About NCT00231309

The ClinicalTrials.gov registry entry for NCT00231309 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,712-participant average among 45 other Hematologic Malignancies trials with a reported enrollment target (100% lower). The listed sponsor is Emory University, which has 1,208 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Hematologic Malignancies appearing as the primary indexed condition, and to 1 intervention - of which Granulocyte Colony Stimulating Factor is the first listed.

NCT00231309 reports 1 study location spanning 1 distinct geographic area - top geographies include Georgia.

Frequently Asked Questions

What is clinical trial NCT00231309 about?

NCT00231309 is a clinical study titled "Granulocyte Colony Stimulating Factor (G-CSF) for Bone Marrow Transplant (BMT)". The major purpose of this study is to evaluate the curative potential of white cell growth hormone (G-CSF)-stimulated bone marrow cells in allogeneic bone marrow transplants. Patients with cancers or blood diseases, who have poor potential for a cure with standard treatment, will be able to particip...

What is the current status of trial NCT00231309?

This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2003-07. Estimated completion is 2011-11.

What conditions does trial NCT00231309 study?

This clinical trial studies the following conditions: Hematologic Malignancies, Hematologic Diseases.

What interventions are being tested in trial NCT00231309?

The interventions under investigation include: Granulocyte Colony Stimulating Factor (DRUG).

Who is sponsoring clinical trial NCT00231309?

This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00231309 being conducted?

This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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