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NCT04249830 · ClinicalTrials.gov registry record · NA
Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Young Adults
A NA study of Hematologic Diseases, sponsored by Alice Bertaina.
- Recruiting
- Registry status
- NA
- Development phase
- 204
- Enrollment target
- 1
- Study location
NCT04249830: Recruiting NA study of Hematologic Diseases, sponsored by Alice Bertaina.
NCT04249830 is a NA study of Hematologic Diseases that is actively recruiting participants, run by Alice Bertaina. The registered enrollment target is 204 participants, below the 2,226-participant average among 17 other Hematologic Diseases trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04249830, a NA study of Hematologic Diseases, is actively recruiting participants, sponsored by Alice Bertaina.
- RECRUITING
- Registry status
- NA
- Development phase
- 204 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of the CliniMACS® TCRαβ-Biotin System and CliniMACS® CD19 is to improve the safety and efficacy of allogeneic HLA-partially matched related or unrelated donors HSCT when no matched donors are available, to treat malignant and nonmalignant disorders for which HSCT is the recommended best available therapy. Initially this device will be used in a single-center, open-label, single-arm, phase II clinical trial to evaluate the efficacy of haploidentical PBSC grafts depleted of TCRα/β+ and CD19+ cells using the CliniMACS® TCRαβ/CD19 System in children and adults with hematological and non-hematological malignancies.
Conditions Studied
Interventions
- BIOLOGICAL Allogeneic Stem Cell Transplant
- DEVICE CliniMACS TCR α/β Reagent Kit and CliniMACS CD19
Study Locations (1)
California
- Lucile Packard Children's Hospital - Palo Alto
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 204 participants |
| Start Date | 2020-02-01 |
| Est. Completion | 2030-12 |
| Phase | NA |
What NCT04249830 shows while recruiting
NCT04249830 is an interventional study that assigns participants to a tested intervention. The registered 204 participants enrollment target is mid-sized for trials with a published cap, below the 2,226-participant average among 17 other Hematologic Diseases trials with a reported enrollment target (91% lower).
The record links to 1 condition, with Hematologic Diseases appearing as the primary indexed condition, and to 2 interventions - of which Allogeneic Stem Cell Transplant is the first listed.
NCT04249830 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT04249830 about?
NCT04249830 is a clinical study titled "Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Young Adults". The purpose of the CliniMACS® TCRαβ-Biotin System and CliniMACS® CD19 is to improve the safety and efficacy of allogeneic HLA-partially matched related or unrelated donors HSCT when no matched donors are available, to treat malignant and nonmalignant disorders for which HSCT is the recommended best ...
What is the current status of trial NCT04249830?
This trial is currently recruiting. It is a NA study. The enrollment target is 204 participants. The study started on 2020-02-01. Estimated completion is 2030-12.
What conditions does trial NCT04249830 study?
This clinical trial studies the following conditions: Hematologic Diseases.
What interventions are being tested in trial NCT04249830?
The interventions under investigation include: Allogeneic Stem Cell Transplant (BIOLOGICAL), CliniMACS TCR α/β Reagent Kit and CliniMACS CD19 (DEVICE).
Who is sponsoring clinical trial NCT04249830?
This trial is sponsored by Alice Bertaina, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04249830 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hematologic Diseases
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04249830's enrollment target sits among peer trials
204 7th of 17 higher than 11 of 17 other Hematologic Diseases trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hematologic Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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