Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04249830 · ClinicalTrials.gov registry record · NA
Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Young Adults
A NA study of Hematologic Diseases, sponsored by Alice Bertaina.
- Recruiting
- Registry status
- NA
- Development phase
- 204
- Enrollment target
- 1
- Study location
NCT04249830 is a NA study of Hematologic Diseases that is actively recruiting participants, run by Alice Bertaina. The registered enrollment target is 204 participants, below the 2,226-participant average among 17 other Hematologic Diseases trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04249830, a NA study of Hematologic Diseases, is actively recruiting participants, sponsored by Alice Bertaina.
- RECRUITING
- Registry status
- NA
- Development phase
- 204 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of the CliniMACS® TCRαβ-Biotin System and CliniMACS® CD19 is to improve the safety and efficacy of allogeneic HLA-partially matched related or unrelated donors HSCT when no matched donors are available, to treat malignant and nonmalignant disorders for which HSCT is the recommended best available therapy. Initially this device will be used in a single-center, open-label, single-arm, phase II clinical trial to evaluate the efficacy of haploidentical PBSC grafts depleted of TCRα/β+ and CD19+ cells using the CliniMACS® TCRαβ/CD19 System in children and adults with hematological and non-hematological malignancies.
Conditions Studied
Interventions
- BIOLOGICAL Allogeneic Stem Cell Transplant
- DEVICE CliniMACS TCR α/β Reagent Kit and CliniMACS CD19
Study Locations (1)
California
- Lucile Packard Children's Hospital - Palo Alto
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 204 participants |
| Start Date | 2020-02-01 |
| Est. Completion | 2030-12 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04249830
The ClinicalTrials.gov registry entry for NCT04249830 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 204 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,226-participant average among 17 other Hematologic Diseases trials with a reported enrollment target (91% lower). The listed sponsor is Alice Bertaina, which has 2 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Hematologic Diseases appearing as the primary indexed condition, and to 2 interventions - of which Allogeneic Stem Cell Transplant is the first listed.
NCT04249830 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT04249830 about?
NCT04249830 is a clinical study titled "Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Young Adults". The purpose of the CliniMACS® TCRαβ-Biotin System and CliniMACS® CD19 is to improve the safety and efficacy of allogeneic HLA-partially matched related or unrelated donors HSCT when no matched donors are available, to treat malignant and nonmalignant disorders for which HSCT is the recommended best ...
What is the current status of trial NCT04249830?
This trial is currently recruiting. It is a NA study. The enrollment target is 204 participants. The study started on 2020-02-01. Estimated completion is 2030-12.
What conditions does trial NCT04249830 study?
This clinical trial studies the following conditions: Hematologic Diseases.
What interventions are being tested in trial NCT04249830?
The interventions under investigation include: Allogeneic Stem Cell Transplant (BIOLOGICAL), CliniMACS TCR α/β Reagent Kit and CliniMACS CD19 (DEVICE).
Who is sponsoring clinical trial NCT04249830?
This trial is sponsored by Alice Bertaina, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04249830 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hematologic Diseases
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
HEME Home Transfusion Program
RECRUITING · NA
-
Multimodal Sexual Dysfunction Intervention In HCT
ACTIVE NOT RECRUITING · NA
-
Granulocyte Colony Stimulating Factor (G-CSF) for Bone Marrow Transplant (BMT)
COMPLETED · NA
-
Implementing an Individualized Pain Plan (IPP) for ED Treatment of VOE's in Sickle Cell Disease
COMPLETED · NA
-
Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Adults With T-allo10 Cells Addback
RECRUITING · Phase 1
-
The Use of Residual De-identified Specimens and/or Samples From Patients for Clinical Research
RECRUITING
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.