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Anemia, Sickle Cell clinical trials
3 of 18 indexed Anemia, Sickle Cell trials are currently recruiting.
18 US clinical trials · 3 currently recruiting
Anemia, Sickle Cell is the subject of 18 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is Duke University, running 2 of these trials.
The research picture
Anemia, Sickle Cell has 18 registered US clinical trials, 3 of them open to new participants right now, about 17% of the total.
- 3
- recruiting participants now
- 17%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Duke University
Active & Recent Trials
18 total, page 1 of 1
A Socio-ecological Approach for Improving Self-management in Adolescents With SCD
Children's Hospital Medical Center, Cincinnati
NCT06290401
A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease
Bristol-Myers Squibb
NCT06481306
Metabolic and Hemodynamic Reserve in Pediatric SCA
Washington University School of Medicine
NCT04406818
Therapeutic Response Evaluation and Adherence Trial (TREAT)
Children's Hospital Medical Center, Cincinnati
NCT02286154
Epidemiology of Silent and Overt Strokes in Sickle Cell Disease
Vanderbilt University Medical Center
NCT03376893
Telemedicine for Children With Sickle Cell Disease
Indiana University
NCT05087303
A Blood Stem Cell Transplant for Sickle Cell Disease
City of Hope Medical Center
NCT03249831
Effectiveness of a Computerized Tool (PAINRelieveIt) to Help Manage Pain Related to Sickle Cell Disease
University of Illinois at Chicago
NCT00600665
Implementing an Individualized Pain Plan (IPP) for ED Treatment of VOE's in Sickle Cell Disease
Duke University
NCT04584528
Nitric Oxide Inhalation to Treat Sickle Cell Pain Crises
Mallinckrodt
NCT00094887
Intranasal Fentanyl for Initial Treatment of a Vaso-occlusive Crisis
Montefiore Medical Center
NCT01482091
Feasibility and Efficacy of a Home-based, Computerized Cognitive Training Program in Pediatric Sickle Cell Disease
Steven J. Hardy
NCT02857023
MBSR for Pain Catastrophizing in SCD
Duke University
NCT02394587
A Self-Management Intervention for Youth With Sickle Cell Disease and Their Families: Phase I
Medical University of South Carolina
NCT03069430
Examining Cognitive Function and Brain Abnormalities in Adults With Sickle Cell Disease - Pilot Intervention Study
UCSF Benioff Children's Hospital Oakland
NCT00850018
Cord Blood Transplantation for Sickle Cell Anemia and Thalassemia
National Heart, Lung, and Blood Institute (NHLBI)
NCT00029380
Hydroxyurea and EPO in Sickle Cell Disease
Julia Xu
NCT05451940
Quality of Life of Children With Sickle Cell Disease Who Are Getting Chronic Transfusions With a Lifeport
Children's Mercy Hospital Kansas City
NCT00246077
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 3 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Anemia, Sickle Cell Trial Landscape
18 indexed Anemia, Sickle Cell studies · 3 recruiting (17%).
Phase mix: 1 late (III/IV) vs 7 early (I/II).
Top sponsor: Duke University (2 trials), 9 others listed. 18 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Anemia, Sickle Cell?
PlainTrial tracks 18 US clinical trials for Anemia, Sickle Cell, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Anemia, Sickle Cell?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.