Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Heart Transplant: early-phase trial registry
7 of 13 indexed Heart Transplant trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,315 of 28,707 conditions by registered trial count.
13 US clinical trials · 7 currently recruiting · #1,315 of 28,707 conditions by registered trial count
Heart Transplant: 13 US clinical trials tracked, 7 recruiting.
Heart Transplant is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is TransMedics, running 6 of these trials.
Enrollment posture brief
Registry condition heart-transplant
OPEN 7 | RECR 54% | LATE 1 | EARLY 2 | RANK #1315 | SPON 6
Volume-matched condition peers
Nearest open-share peer: Advanced Renal Cell Carcinoma (54% recruiting · 13 trials)
Heart Transplant lists 7 open slots (54% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Heart Transplant on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Heart Transplant is recruiting above its size-band peers.
7 of 13 indexed trials (53.8%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Heart Transplant research.
TransMedics accounts for 6 of 13 trials (46.2%). 8 distinct sponsors appear on at least one study for this condition label.
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Typical Heart Transplant enrolment sits around 147 participants.
Median target enrolment is 147 among the 13 trials that report a genuine target (sentinel values excluded). 6 of those (46.2%) plan for fewer than 100 participants.
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Heart Transplant splits between interventional and observational designs.
9 interventional and 4 observational studies make up this index (69.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
13 total, page 1 of 1
US National OCS Heart Perfusion (OHP) Registry
TransMedics
NCT05915299
Enhancing Heart Allograft Function With the OCS Heart System Trial
TransMedics
NCT07145515
MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation
University of California, San Francisco
NCT05933083
Randomized Trial of SGLT2i in Heart Transplant Recipients
VA Office of Research and Development
NCT06625073
Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise
Masonic Cancer Center, University of Minnesota
NCT05025774
Belatacept in Heart Transplantation
National Institute of Allergy and Infectious Diseases (NIAID)
NCT06478017
XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)
XVIVO Perfusion
NCT06895070
OCS DCD Heart + CAP Continued Follow-Up
TransMedics
NCT05741723
Expanding the Pool in Orthotopic Heart Transplantation
Mary E. Keebler, MD
NCT03222531
Donors After Circulatory Death Heart Trial
TransMedics
NCT03831048
Development of Non-invasive Cell-free DNA to Supplant Invasive Biopsy in Heart Transplantation
Natera
NCT05309382
Heart EXPAND Continued Access Protocol
TransMedics
NCT03835754
International EXPAND Heart Pivotal Trial
TransMedics
NCT02323321
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 2 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Heart Transplant records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Heart Transplant trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Heart Transplant page
13 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 7 Heart Transplant trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- TransMedics sponsors the most Heart Transplant trials on record, review their full trial history before evaluating a specific study. See TransMedics's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Heart Transplant condition card totals 13 registered trials; most-linked intervention OCS Heart; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.