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ClinicalTrials.gov 6 recruiting now early-phase tilt small index

Acute Biphenotypic Leukemia: early-phase trial registry

6 of 13 indexed Acute Biphenotypic Leukemia trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,315 of 28,707 conditions by registered trial count.

13 US clinical trials · 6 currently recruiting · #1,315 of 28,707 conditions by registered trial count

Acute Biphenotypic Leukemia: 13 US clinical trials tracked, 6 recruiting.

Acute Biphenotypic Leukemia is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 6 of these trials.

Enrollment posture brief

Registry condition acute-biphenotypic-leukemia

OPEN 6 | RECR 46% | LATE 0 | EARLY 13 | RANK #1315 | SPON 6

Nearest open-share peer: B-cell Lymphoma (46% recruiting · 39 trials)

ACL Injury61.5%Acute Biphenotypic Leuke (th…46%Accidental Falls30.8%Acute Decompensated Heart Fa30.8%Actinic Keratoses23.1%
Open-enrollment share among volume-matched conditions near Acute Biphenotypic Leukemia

Acute Biphenotypic Leukemia lists 6 open slots (46% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Acute Biphenotypic Leukemia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Acute Biphenotypic Leukemia recruits in line with its size-band peers.

    6 of 13 indexed trials (46.2%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Acute Biphenotypic Leukemia research.

    M.D. Anderson Cancer Center accounts for 6 of 13 trials (46.2%). 6 distinct sponsors appear on at least one study for this condition label.

  3. Most Acute Biphenotypic Leukemia trials plan to enrol fewer than 100 people.

    Median target enrolment is 62 among the 13 trials that report a genuine target (sentinel values excluded). 8 of those (61.5%) plan for fewer than 100 participants.

  4. Acute Biphenotypic Leukemia research is mostly interventional.

    13 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 29

Open and recent trials

13 total, page 1 of 1

RECRUITING Phase 2 508 participants

Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia

M.D. Anderson Cancer Center

NCT02115295

RECRUITING Phase 2 100 participants

Personalized NK Cell Therapy in CBT

M.D. Anderson Cancer Center

NCT02727803

RECRUITING Phase 2 68 participants

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Fred Hutchinson Cancer Center

NCT03779854

RECRUITING Phase 1 62 participants

Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid Neoplasms

University of Washington

NCT04797767

RECRUITING Phase 2 50 participants

Enasidenib and Azacitidine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia and IDH2 Gene Mutation

M.D. Anderson Cancer Center

NCT03683433

RECRUITING Phase 1 12 participants

A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies

Ossium Health

NCT05589896

ACTIVE NOT RECRUITING Phase 2 100 participants

Venetoclax and Azacitidine for the Treatment of Acute Myeloid Leukemia in the Post-Transplant Setting

M.D. Anderson Cancer Center

NCT04128501

ACTIVE NOT RECRUITING Phase 2 31 participants

Infusion of Expanded Cord Blood Cells in Addition to Single Cord Blood Transplant in Treating Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplastic Syndromes

Fred Hutchinson Cancer Center

NCT03399773

ACTIVE NOT RECRUITING Phase 1 31 participants

Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia and Persistent/Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm

City of Hope Medical Center

NCT02159495

COMPLETED Phase 1 199 participants

Filgrastim, Cladribine, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Newly Diagnosed or Relapsed/Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Fred Hutchinson Cancer Center

NCT02044796

COMPLETED Phase 2 150 participants

Nivolumab and Azacitidine With or Without Ipilimumab in Treating Patients With Refractory/Relapsed or Newly Diagnosed Acute Myeloid Leukemia

M.D. Anderson Cancer Center

NCT02397720

COMPLETED Phase 2 16 participants

Clofarabine, Idarubicin, Cytarabine, Vincristine Sulfate, and Dexamethasone in Treating Patients With Newly Diagnosed or Relapsed Mixed Phenotype Acute Leukemia

M.D. Anderson Cancer Center

NCT02135874

COMPLETED Phase 2 8 participants

Ibrutinib in Preventing Acute Leukemia in Patients After Reduced-Intensity Conditioning and Stem Cell Transplant

Andrew Rezvani

NCT03267186

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 9

Named interventions

Most-linked intervention names on Acute Biphenotypic Leukemia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Cytarabine Drug
4 trials
Laboratory Biomarker Analysis Other
3 trials
Azacitidine Drug
3 trials
Cladribine Drug
3 trials
Cyclophosphamide Drug
3 trials
Venetoclax Drug
3 trials
Clofarabine Drug
2 trials
Idarubicin Drug
2 trials

US sites by state

Facility locations filed on Acute Biphenotypic Leukemia trials. A trial with sites in several states counts in each.

Texas 7 trials
Washington 4 trials
California 4 trials
Oregon 2 trials
Georgia 2 trials
Utah 1 trials
Tennessee 1 trials
Pennsylvania 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Acute Biphenotypic Leukemia page

13 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Acute Biphenotypic Leukemia condition card totals 13 registered trials; most-linked intervention Cytarabine; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.