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ClinicalTrials.gov 6 recruiting now official registry

Acute Biphenotypic Leukemia clinical trials

6 of 13 indexed Acute Biphenotypic Leukemia trials are currently recruiting.

13 US clinical trials · 6 currently recruiting

Acute Biphenotypic Leukemia is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 6 of these trials.

The research picture

Acute Biphenotypic Leukemia has 13 registered US clinical trials, 6 of them open to new participants right now, about 46% of the total.

6
recruiting participants now
46%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
6
top sponsor: M.D. Anderson Cancer Center
Phase 14Phase 29

Active & Recent Trials

13 total, page 1 of 1

RECRUITING Phase 2 508 participants

Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia

M.D. Anderson Cancer Center

NCT02115295

RECRUITING Phase 2 100 participants

Personalized NK Cell Therapy in CBT

M.D. Anderson Cancer Center

NCT02727803

RECRUITING Phase 2 68 participants

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Fred Hutchinson Cancer Center

NCT03779854

RECRUITING Phase 1 62 participants

Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid Neoplasms

University of Washington

NCT04797767

RECRUITING Phase 2 50 participants

Enasidenib and Azacitidine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia and IDH2 Gene Mutation

M.D. Anderson Cancer Center

NCT03683433

RECRUITING Phase 1 12 participants

A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies

Ossium Health

NCT05589896

ACTIVE NOT RECRUITING Phase 2 100 participants

Venetoclax and Azacitidine for the Treatment of Acute Myeloid Leukemia in the Post-Transplant Setting

M.D. Anderson Cancer Center

NCT04128501

ACTIVE NOT RECRUITING Phase 2 31 participants

Infusion of Expanded Cord Blood Cells in Addition to Single Cord Blood Transplant in Treating Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplastic Syndromes

Fred Hutchinson Cancer Center

NCT03399773

ACTIVE NOT RECRUITING Phase 1 31 participants

Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia and Persistent/Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm

City of Hope Medical Center

NCT02159495

COMPLETED Phase 1 199 participants

Filgrastim, Cladribine, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Newly Diagnosed or Relapsed/Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Fred Hutchinson Cancer Center

NCT02044796

COMPLETED Phase 2 150 participants

Nivolumab and Azacitidine With or Without Ipilimumab in Treating Patients With Refractory/Relapsed or Newly Diagnosed Acute Myeloid Leukemia

M.D. Anderson Cancer Center

NCT02397720

COMPLETED Phase 2 16 participants

Clofarabine, Idarubicin, Cytarabine, Vincristine Sulfate, and Dexamethasone in Treating Patients With Newly Diagnosed or Relapsed Mixed Phenotype Acute Leukemia

M.D. Anderson Cancer Center

NCT02135874

COMPLETED Phase 2 8 participants

Ibrutinib in Preventing Acute Leukemia in Patients After Reduced-Intensity Conditioning and Stem Cell Transplant

Andrew Rezvani

NCT03267186

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 9

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Acute Biphenotypic Leukemia Trial Landscape

13 indexed Acute Biphenotypic Leukemia studies · 6 recruiting (46%).

Phase mix: 0 late (III/IV) vs 13 early (I/II).

Top sponsor: M.D. Anderson Cancer Center (6 trials), 5 others listed. 13 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Acute Biphenotypic Leukemia?

PlainTrial tracks 13 US clinical trials for Acute Biphenotypic Leukemia, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Acute Biphenotypic Leukemia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.