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NCT05915299 · ClinicalTrials.gov registry record
US National OCS Heart Perfusion (OHP) Registry
A clinical trial of Heart Transplant, sponsored by TransMedics.
- Recruiting
- Registry status
- 100,000
- Enrollment target
- 20
- Study locations
NCT05915299: Recruiting study of Heart Transplant, sponsored by TransMedics.
NCT05915299 is a study of Heart Transplant that is actively recruiting participants, run by TransMedics. The registered enrollment target is 100,000 participants, above the 197-participant average among 12 other Heart Transplant trials with a reported enrollment target (50661% higher). The trial reports 20 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05915299, a study of Heart Transplant, is actively recruiting participants, sponsored by TransMedics.
- RECRUITING
- Registry status
- 100,000 participants
- Enrollment target
- 20
- Study locations
Study Summary
This Registry is a sponsor initiated, multi-center, observational post-approval registry with independent academic oversight.
Primary Outcome
Recipients' patient and graft survival rates will be the primary clinical outcomes measures for all OCS Heart transplanted recipients compared to recipients receiving heart transplants using non-OCS preservation methods (cold static storage or other perfusion devices or a combination of both). This data will be obtained directly from UNOS/OPTN database.
Conditions Studied
Interventions
- DEVICE OCS Heart
Study Locations (20)
California
- University of California San Diego - La Jolla
- Lucile Packard Children's Hospital Stanford - Palo Alto
- Stanford University - Palo Alto
- University of California San Francisco - San Francisco
Massachusetts
- Tufts Medical Center - Boston
- Massachusetts General Hospital - Boston
- Beth Israel Deaconess Medical Center - Boston
Minnesota
- Minneapolis Heart Institute - Minneapolis
- University of Minnesota - Minneapolis
- Mayo Clinic Rochester - Rochester
Florida
- Mayo Clinic Florida - Jacksonville
- Tampa General Hospital - Tampa
Michigan
- University of Michigan - Ann Arbor
- Henry Ford - Detroit
Arizona
- Banner University Medical Center Phoenix - Phoenix
Colorado
- Boulder - Boulder
Connecticut
- Yale New Haven Hospital - New Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100,000 participants |
| Start Date | 2023-08-25 |
| Est. Completion | 2033-08-31 |
What NCT05915299 shows while recruiting
NCT05915299 is an observational study that tracks outcomes without assigning an intervention. Its 100,000 participants enrollment target places it among the larger protocols in the corpus, above the 197-participant average among 12 other Heart Transplant trials with a reported enrollment target (50661% higher).
The record links to 1 condition, with Heart Transplant appearing as the primary indexed condition, and to 1 intervention - of which OCS Heart is the first listed.
NCT05915299 names 20 study sites across 11 states, led by California, Massachusetts, Minnesota.
Frequently Asked Questions
What is clinical trial NCT05915299 about?
NCT05915299 is a clinical study titled "US National OCS Heart Perfusion (OHP) Registry". This Registry is a sponsor initiated, multi-center, observational post-approval registry with independent academic oversight.
What is the current status of trial NCT05915299?
This trial is currently recruiting. The enrollment target is 100,000 participants. The study started on 2023-08-25. Estimated completion is 2033-08-31.
What conditions does trial NCT05915299 study?
This clinical trial studies the following conditions: Heart Transplant.
What interventions are being tested in trial NCT05915299?
The interventions under investigation include: OCS Heart (DEVICE).
Who is sponsoring clinical trial NCT05915299?
This trial is sponsored by TransMedics, which has 23 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05915299 being conducted?
This trial has 20 study locations across Arizona, California, Colorado, Connecticut, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Heart Transplant
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05915299's enrollment target sits among peer trials
100,000 1st of 12 higher than 12 of 12 other Heart Transplant trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Heart Transplant trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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