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NCT05309382 · ClinicalTrials.gov registry record
Development of Non-invasive Cell-free DNA to Supplant Invasive Biopsy in Heart Transplantation
A clinical trial of Heart Transplant, sponsored by Natera.
- Completed
- Registry status
- 147
- Enrollment target
- 9
- Study locations
NCT05309382 is a study of Heart Transplant that has completed, run by Natera. The registered enrollment target is 147 participants, below the 8,518-participant average among 12 other Heart Transplant trials with a reported enrollment target (98% lower). The trial reports 9 study locations across 8 states.
The verdict
NCT05309382, a study of Heart Transplant, has completed, sponsored by Natera.
- COMPLETED
- Registry status
- 147 participants
- Enrollment target
- 9
- Study locations
Study Summary
This is a prospective, multicenter observational, unblinded, longitudinal cohort study. Subjects will be enrolled into the study prior to or at the time of heart transplantation. All subjects will follow the center's standard of care surveillance schedule. Blood samples will be collected for Prospera testing at the time any surveillance or for-cause testing, which may include endomyocardial biopsy (EMB), echocardiography or other cardiac imaging studies, and/or molecular testing, is performed.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Prospera
Study Locations (9)
California
- Cedars-Sinai Medical Center - Los Angeles
- University of California, San Diego - San Diego
Florida
- Mayo Clinic - Jacksonville
Illinois
- Northwestern Memorial Hospital - Chicago
Massachusetts
- Brigham and Women's Hospital - Boston
Ohio
- Cleveland Clinic Foundation - Cleveland
Tennessee
- Vanderbilt University Medical Center - Nashville
Utah
- University of Utah - Salt Lake City
Virginia
- Inova Heart and Vascular Institute - Falls Church
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 147 participants |
| Start Date | 2022-12-12 |
| Est. Completion | 2024-10-02 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05309382
The ClinicalTrials.gov registry entry for NCT05309382 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 147 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 8,518-participant average among 12 other Heart Transplant trials with a reported enrollment target (98% lower). The listed sponsor is Natera, which has 27 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Heart Transplant appearing as the primary indexed condition, and to 1 intervention - of which Prospera is the first listed.
NCT05309382 reports 9 study locations spanning 8 distinct geographic areas - top geographies include California, Florida, Illinois.
Frequently Asked Questions
What is clinical trial NCT05309382 about?
NCT05309382 is a clinical study titled "Development of Non-invasive Cell-free DNA to Supplant Invasive Biopsy in Heart Transplantation". This is a prospective, multicenter observational, unblinded, longitudinal cohort study. Subjects will be enrolled into the study prior to or at the time of heart transplantation. All subjects will follow the center's standard of care surveillance schedule. Blood samples will be collected for Prosper...
What is the current status of trial NCT05309382?
This trial is currently completed. The enrollment target is 147 participants. The study started on 2022-12-12. Estimated completion is 2024-10-02.
What conditions does trial NCT05309382 study?
This clinical trial studies the following conditions: Heart Transplant.
What interventions are being tested in trial NCT05309382?
The interventions under investigation include: Prospera (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT05309382?
This trial is sponsored by Natera, which has 27 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05309382 being conducted?
This trial has 9 study locations across California, Florida, Illinois, Massachusetts, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.