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ClinicalTrials.gov 7 recruiting now official registry

Advanced Renal Cell Carcinoma clinical trials

7 of 13 indexed Advanced Renal Cell Carcinoma trials are currently recruiting.

13 US clinical trials · 7 currently recruiting

Advanced Renal Cell Carcinoma is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 2 of these trials.

The research picture

Advanced Renal Cell Carcinoma has 13 registered US clinical trials, 7 of them open to new participants right now, about 54% of the total.

7
recruiting participants now
54%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
2
top sponsor: M.D. Anderson Cancer Center
Phase 17Phase 25

Active & Recent Trials

13 total, page 1 of 1

RECRUITING Phase 1 224 participants

A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

Pfizer

NCT07227415

RECRUITING Phase 1 100 participants

The Immune Effects of Fermented Wheat Germ Nutritional Supplementation in Patients With Advanced Solid Tumor Cancers Being Treated With Standard of Care Checkpoint Inhibitors

University of California, Davis

NCT05967533

RECRUITING Phase 2 70 participants

Trial of Zanzalintinib (XL092) in Combination With Immunotherapy in Patients Who Progress on Adjuvant Therapy in Clear Cell RCC

Karie Runcie

NCT06863311

RECRUITING Phase 2 50 participants

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

Mayo Clinic

NCT06265285

RECRUITING Phase 1 50 participants

Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma

M.D. Anderson Cancer Center

NCT05703854

RECRUITING Phase 1 43 participants

Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax

M.D. Anderson Cancer Center

NCT05092373

RECRUITING Phase 1 28 participants

CBM588 Capsules in Combination With Nivolumab and Ipilimumab for the Treatment of Advanced Stage Kidney Cancer

Osel

NCT06399419

ACTIVE NOT RECRUITING NA 156 participants

PROMOTE: Identifying Predictive Markers of Response for Genitourinary Cancer

University of California, San Francisco

NCT02735252

ACTIVE NOT RECRUITING Phase 2 134 participants

Testing the Addition of a New Anti-cancer Drug, Radium-223 Dichloride, to the Usual Treatment (Cabozantinib) for Advanced Renal Cell Cancer That Has Spread to the Bone, RadiCaL Study

National Cancer Institute (NCI)

NCT04071223

ACTIVE NOT RECRUITING Phase 1 67 participants

A Study to Evaluate MEDI5752 and Axitinib in Subjects With Advanced Renal Cell Carcinoma

MedImmune

NCT04522323

ACTIVE NOT RECRUITING Phase 1 31 participants

CBM588 in Combination With Nivolumab and Cabozantinib for the Treatment of Advanced or Metastatic Kidney Cancer

City of Hope Medical Center

NCT05122546

ACTIVE NOT RECRUITING Phase 2 9 participants

Study of Nivolumab in Combination With 177Lu-girentuximab for Kidney Cancer

Memorial Sloan Kettering Cancer Center

NCT05239533

COMPLETED Phase 2 164 participants

Study of Front Line Therapy With Nivolumab and Salvage Nivolumab + Ipilimumab in Patients With Advanced Renal Cell Carcinoma

Michael B. Atkins, MD

NCT03117309

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 5

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Advanced Renal Cell Carcinoma Trial Landscape

13 indexed Advanced Renal Cell Carcinoma studies · 7 recruiting (54%).

Phase mix: 0 late (III/IV) vs 12 early (I/II).

Top sponsor: M.D. Anderson Cancer Center (2 trials), 9 others listed. 13 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Advanced Renal Cell Carcinoma?

PlainTrial tracks 13 US clinical trials for Advanced Renal Cell Carcinoma, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Advanced Renal Cell Carcinoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.